SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 TRP A 114
TYR A  90
LEU A  61
 EDO  A 262 (-4.1A)
None
None
 1.08A 1kxhA-3l1wA:
undetectable		 1kxhA-3l1wA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 LEU A 245
ASP A 215
ILE A 214
TYR A 218
HIS A 176
 None
 1.23A 1s9aA-3l1wA:
undetectable		 1s9aA-3l1wA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 LEU A 245
ASP A 215
ILE A 214
TYR A 218
HIS A 176
 None
 1.30A 1s9aA-3l1wA:
undetectable		 1s9aA-3l1wA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 ALA A 247
SER A 229
THR A 227
VAL A 224
 None
 0.80A 3d2tB-3l1wA:
undetectable		 3d2tB-3l1wA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A 245
ASP A 215
ILE A 214
TYR A 218
HIS A 176
 None
 1.25A 3hgiA-3l1wA:
undetectable		 3hgiA-3l1wA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 VAL A  27
TYR A   6
TRP A  20
GLU A  43
 None
 1.09A 3hs4A-3l1wA:
undetectable		 3hs4A-3l1wA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 4 ILE A 102
SER A 101
ASP A 134
ASP A 166
 None
 1.26A 4krhB-3l1wA:
2.6		 4krhB-3l1wA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 HIS A 132
ASP A 166
ASN A 168
ILE A 214
HIS A 242
 None
 0.23A 5dv4A-3l1wA:
25.9		 5dv4A-3l1wA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 LEU A 149
LEU A 152
TRP A 114
 None
None
EDO  A 262 (-4.1A)
 0.91A 5nwuA-3l1wA:
undetectable		 5nwuA-3l1wA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 3l1w UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 THR A   5
THR A 198
VAL A  49
GLU A  72
GLY A  73
 None
 1.43A 6gngB-3l1wA:
undetectable		 6gngB-3l1wA:
15.75