SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 VAL A 173
ALA A 170
HIS A 167
 None
 0.78A 1q23C-3l23A:
undetectable		 1q23C-3l23A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 VAL A 173
ALA A 170
HIS A 167
 None
 0.78A 1q23L-3l23A:
undetectable		 1q23L-3l23A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 ALA A 143
ASP A 147
MET A  92
TYR A  82
 EDO  A   4 ( 3.8A)
None
None
EDO  A   4 (-4.5A)
 1.48A 2pncB-3l23A:
undetectable		 2pncB-3l23A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 HIS A 198
MET A 200
MET A 160
 None
 1.11A 2vj1A-3l23A:
undetectable		 2vj1A-3l23A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 5 ALA A 145
GLY A 152
CYH A 153
LYS A 154
 None
 1.45A 2ylgA-3l23A:
undetectable		 2ylgA-3l23A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 TYR A 243
TYR A 155
CYH A 153
ILE A 189
 None
 1.24A 4bqtC-3l23A:
undetectable
4bqtD-3l23A:
undetectable		 4bqtC-3l23A:
20.32
4bqtD-3l23A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 TYR A 155
HIS A 110
GLU A  78
HIS A 273
TYR A 243
 None
None
None
MG  A   1 (-3.3A)
None
 1.23A 4r7lA-3l23A:
undetectable		 4r7lA-3l23A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 5 ALA A 145
GLY A 152
CYH A 153
LYS A 154
 None
 1.44A 5jliA-3l23A:
undetectable		 5jliA-3l23A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 9 VAL A 305
LEU A  48
MET A 310
ALA A 324
MET A  72
 None
 1.04A 5og9A-3l23A:
undetectable		 5og9A-3l23A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3l23 SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 305
LEU A  48
MET A 310
ALA A 324
MET A  72
 None
 1.00A 5og9B-3l23A:
undetectable		 5og9B-3l23A:
21.41