SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 3l2a POLYMERASE COFACTOR
VP35
(Reston
ebolavirus) 		4 / 8 LEU A 231
ILE A 309
ILE A 235
ILE A 238
 None
 0.79A 2bu8A-3l2aA:
undetectable		 2bu8A-3l2aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3l2a POLYMERASE COFACTOR
VP35
(Reston
ebolavirus) 		6 / 12 ILE A 235
GLN A 233
LEU A 231
VAL A 273
ILE A 275
LEU A 245
 None
GOL  A   3 (-3.7A)
None
None
None
None
 1.12A 3oapA-3l2aA:
undetectable		 3oapA-3l2aA:
19.66