SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3l2b PROBABLE
MANGANASE-DEPENDENT
INORGANIC
PYROPHOSPHATASE
(Clostridium
perfringens) 		4 / 5 ARG A 158
GLY A 182
GLY A 163
PRO A 162
 None
 0.87A 4u9uA-3l2bA:
undetectable		 4u9uA-3l2bA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3l2b PROBABLE
MANGANASE-DEPENDENT
INORGANIC
PYROPHOSPHATASE
(Clostridium
perfringens) 		4 / 5 ARG A 158
GLY A 182
GLY A 163
PRO A 162
 None
 0.98A 4u9uB-3l2bA:
undetectable		 4u9uB-3l2bA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3l2b PROBABLE
MANGANASE-DEPENDENT
INORGANIC
PYROPHOSPHATASE
(Clostridium
perfringens) 		5 / 12 ASP A 189
ALA A 168
LEU A 197
ALA A 195
LEU A 175
 None
 1.02A 6bq4A-3l2bA:
undetectable		 6bq4A-3l2bA:
14.11