SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.34A 1a52A-3l2zA:
undetectable		 1a52A-3l2zA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.33A 1a52B-3l2zA:
undetectable		 1a52B-3l2zA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 153
ALA A 108
ASP A 111
ILE A 199
VAL A  86
 None
 1.04A 1d4yA-3l2zA:
undetectable		 1d4yA-3l2zA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.35A 1ereA-3l2zA:
undetectable		 1ereA-3l2zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.35A 1ereB-3l2zA:
undetectable		 1ereB-3l2zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.34A 1ereC-3l2zA:
undetectable		 1ereC-3l2zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 105
LEU A 153
LEU A 143
ILE A  83
LEU A 190
 None
 1.35A 1ereD-3l2zA:
undetectable		 1ereD-3l2zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 108
ASP A 111
LEU A 110
LEU A 153
LEU A 208
 None
 1.14A 1errA-3l2zA:
undetectable		 1errA-3l2zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  50
ALA A  51
VAL A  56
VAL A 152
ILE A  53
 None
 0.99A 1hsgB-3l2zA:
undetectable		 1hsgB-3l2zA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 ILE A 186
LEU A 190
VAL A 155
ALA A 144
 None
 0.99A 1mz9A-3l2zA:
undetectable		 1mz9A-3l2zA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ILE A 186
LEU A 190
VAL A 155
ALA A 144
 None
 0.91A 1mz9C-3l2zA:
undetectable		 1mz9C-3l2zA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.13A 1pxxA-3l2zA:
undetectable		 1pxxA-3l2zA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 126
VAL A 109
GLY A 106
ALA A 105
SER A 102
 None
 1.24A 1pxxB-3l2zA:
undetectable		 1pxxB-3l2zA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 126
VAL A 109
GLY A 106
ALA A 105
SER A 102
 None
 1.23A 1pxxD-3l2zA:
1.5		 1pxxD-3l2zA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 132
ALA A 134
ILE A  82
LEU A 190
THR A 124
 None
 1.09A 1qzfA-3l2zA:
undetectable		 1qzfA-3l2zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 132
ALA A 134
ILE A  82
LEU A 190
THR A 124
 None
 1.10A 1qzfB-3l2zA:
undetectable		 1qzfB-3l2zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 132
ALA A 134
ILE A  82
LEU A 190
THR A 124
 None
 1.10A 1qzfC-3l2zA:
undetectable		 1qzfC-3l2zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 132
ALA A 134
ILE A  82
LEU A 190
THR A 124
 None
 1.09A 1qzfD-3l2zA:
undetectable		 1qzfD-3l2zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 132
ALA A 134
ILE A  82
LEU A 190
THR A 124
 None
 1.10A 1qzfE-3l2zA:
undetectable		 1qzfE-3l2zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 154
VAL A 155
GLY A 156
THR A  39
VAL A  86
 None
 1.32A 1v3qE-3l2zA:
undetectable		 1v3qE-3l2zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  16
ILE A 186
ALA A 187
THR A  39
VAL A  32
 None
 1.16A 2g78A-3l2zA:
undetectable		 2g78A-3l2zA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 THR A  36
ASP A  42
SER A  85
VAL A  57
 None
 1.12A 2hdnI-3l2zA:
undetectable
2hdnJ-3l2zA:
undetectable
2hdnL-3l2zA:
undetectable		 2hdnI-3l2zA:
7.92
2hdnJ-3l2zA:
25.42
2hdnL-3l2zA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 153
ALA A 108
ASP A 111
ILE A 199
VAL A  86
 None
 1.01A 2hs2B-3l2zA:
undetectable		 2hs2B-3l2zA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 153
ALA A 108
ASP A 111
ILE A 199
VAL A  86
 None
 1.03A 2o4pA-3l2zA:
undetectable		 2o4pA-3l2zA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  50
ALA A  51
VAL A  56
VAL A 152
ILE A  53
 None
 1.03A 2qhcB-3l2zA:
undetectable		 2qhcB-3l2zA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  50
ALA A  51
VAL A  56
VAL A 152
ILE A  53
 None
 1.06A 2z54A-3l2zA:
undetectable		 2z54A-3l2zA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 153
ALA A 108
ASP A 111
ILE A 199
VAL A  86
 None
 0.94A 3el1A-3l2zA:
undetectable		 3el1A-3l2zA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 ARG A 189
LEU A 116
ASP A 175
VAL A 132
ILE A 117
 None
 1.23A 3oxxB-3l2zA:
undetectable		 3oxxB-3l2zA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 190
ALA A 105
ILE A  82
ILE A  83
LEU A  84
 None
 0.85A 4nkvB-3l2zA:
undetectable		 4nkvB-3l2zA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.01A 4rrxA-3l2zA:
undetectable		 4rrxA-3l2zA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.02A 4rrxB-3l2zA:
undetectable		 4rrxB-3l2zA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 108
ASP A 111
LEU A 110
LEU A 153
LEU A 208
 None
 1.16A 4xi3A-3l2zA:
undetectable		 4xi3A-3l2zA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  59
VAL A 155
ALA A 104
ALA A 105
VAL A 109
 None
 0.90A 5igjA-3l2zA:
undetectable		 5igjA-3l2zA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  59
VAL A 155
ALA A 104
ALA A 105
VAL A 109
 None
 0.87A 5igtA-3l2zA:
undetectable		 5igtA-3l2zA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.08A 5ikqA-3l2zA:
undetectable		 5ikqA-3l2zA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.08A 5ikqB-3l2zA:
undetectable		 5ikqB-3l2zA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  86
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 0.95A 5iktA-3l2zA:
undetectable		 5iktA-3l2zA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 208
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 1.04A 5iktB-3l2zA:
undetectable		 5iktB-3l2zA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  86
LEU A 126
GLY A 106
ALA A 105
LEU A 194
 None
 0.94A 5iktB-3l2zA:
undetectable		 5iktB-3l2zA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 VAL A 109
ILE A 186
LEU A 190
ILE A  82
ASN A 158
 None
 0.98A 5nunA-3l2zA:
undetectable		 5nunA-3l2zA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 108
GLU A 193
ARG A 189
GLY A 125
LEU A 126
 None
 1.46A 5wgqA-3l2zA:
undetectable		 5wgqA-3l2zA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 217
GLY A 125
VAL A 155
VAL A 109
ASP A 111
 None
 1.36A 6bxlB-3l2zA:
undetectable		 6bxlB-3l2zA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 3l2z BIRA BIFUNCTIONAL
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 153
ALA A 108
ASP A 111
ILE A 199
VAL A  86
 None
 0.99A 6dilA-3l2zA:
undetectable		 6dilA-3l2zA:
14.50