SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  41
ARG A  46
ILE A 105
 PO4  A 219 (-4.3A)
None
None
 0.76A 1a4gB-3l39A:
undetectable		 1a4gB-3l39A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  93
ASP A  61
ASP A  86
 None
 0.74A 1eizA-3l39A:
undetectable		 1eizA-3l39A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  93
ASP A  61
ASP A  86
 None
 0.73A 1ej0A-3l39A:
undetectable		 1ej0A-3l39A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY A  60
LEU A  63
THR A  64
VAL A  26
 None
 0.99A 1ekjF-3l39A:
undetectable
1ekjG-3l39A:
undetectable		 1ekjF-3l39A:
17.32
1ekjG-3l39A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 138
PHE A  79
LEU A 207
SER A  89
 None
 0.85A 1wrlE-3l39A:
undetectable
1wrlF-3l39A:
undetectable		 1wrlE-3l39A:
17.83
1wrlF-3l39A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 SER A 114
ILE A 105
LEU A 168
ASP A 163
GLU A 159
 PO4  A 220 (-2.8A)
None
None
None
None
 1.39A 3aocC-3l39A:
undetectable		 3aocC-3l39A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A  34
GLU A 192
ILE A 189
 None
PO4  A 217 ( 4.9A)
None
 0.52A 3czhA-3l39A:
undetectable		 3czhA-3l39A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  93
ASP A  61
ASP A  86
 None
 0.69A 3douA-3l39A:
undetectable		 3douA-3l39A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 107
ILE A 189
TYR A 108
GLU A 188
 None
None
None
PO4  A 217 (-4.3A)
 1.23A 4zzcE-3l39A:
7.8		 4zzcE-3l39A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A  84
ALA A  88
LEU A  87
ILE A 206
 None
 0.87A 5mvmB-3l39A:
7.7
5mvmC-3l39A:
7.7		 5mvmB-3l39A:
16.36
5mvmC-3l39A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 105
VAL A 203
LEU A 155
GLY A 117
LEU A  34
 None
 0.99A 6a7pA-3l39A:
2.1		 6a7pA-3l39A:
15.28