SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 1k2rA-3l3pA:
undetectable
1k2rB-3l3pA:
undetectable		 1k2rA-3l3pA:
20.70
1k2rB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.28A 1k2rA-3l3pA:
undetectable
1k2rB-3l3pA:
undetectable		 1k2rA-3l3pA:
20.70
1k2rB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 1k2sA-3l3pA:
undetectable
1k2sB-3l3pA:
undetectable		 1k2sA-3l3pA:
20.70
1k2sB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 1k2sA-3l3pA:
undetectable
1k2sB-3l3pA:
undetectable		 1k2sA-3l3pA:
20.70
1k2sB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 1k2tA-3l3pA:
undetectable
1k2tB-3l3pA:
undetectable		 1k2tA-3l3pA:
20.70
1k2tB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.28A 1k2tA-3l3pA:
undetectable
1k2tB-3l3pA:
undetectable		 1k2tA-3l3pA:
20.70
1k2tB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1k2uA-3l3pA:
undetectable
1k2uB-3l3pA:
undetectable		 1k2uA-3l3pA:
20.70
1k2uB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.28A 1k2uA-3l3pA:
undetectable
1k2uB-3l3pA:
undetectable		 1k2uA-3l3pA:
20.70
1k2uB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 1lzxA-3l3pA:
3.7
1lzxB-3l3pA:
undetectable		 1lzxA-3l3pA:
20.70
1lzxB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.27A 1lzxA-3l3pA:
3.7
1lzxB-3l3pA:
undetectable		 1lzxA-3l3pA:
20.70
1lzxB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.27A 1lzzA-3l3pA:
undetectable
1lzzB-3l3pA:
undetectable		 1lzzA-3l3pA:
20.70
1lzzB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 1lzzA-3l3pA:
undetectable
1lzzB-3l3pA:
undetectable		 1lzzA-3l3pA:
20.70
1lzzB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1m00A-3l3pA:
undetectable
1m00B-3l3pA:
undetectable		 1m00A-3l3pA:
20.70
1m00B-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 1m00A-3l3pA:
undetectable
1m00B-3l3pA:
undetectable		 1m00A-3l3pA:
20.70
1m00B-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 1mmvA-3l3pA:
undetectable
1mmvB-3l3pA:
undetectable		 1mmvA-3l3pA:
20.70
1mmvB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.25A 1mmwA-3l3pA:
undetectable
1mmwB-3l3pA:
3.8		 1mmwA-3l3pA:
20.70
1mmwB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.29A 1mmwA-3l3pA:
undetectable
1mmwB-3l3pA:
3.8		 1mmwA-3l3pA:
20.70
1mmwB-3l3pA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 1om4A-3l3pA:
3.2
1om4B-3l3pA:
undetectable		 1om4A-3l3pA:
20.60
1om4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.29A 1om4A-3l3pA:
3.2
1om4B-3l3pA:
undetectable		 1om4A-3l3pA:
20.60
1om4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 1om5A-3l3pA:
undetectable
1om5B-3l3pA:
undetectable		 1om5A-3l3pA:
20.65
1om5B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 1om5A-3l3pA:
undetectable
1om5B-3l3pA:
undetectable		 1om5A-3l3pA:
20.65
1om5B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1p6hA-3l3pA:
undetectable
1p6hB-3l3pA:
undetectable		 1p6hA-3l3pA:
20.65
1p6hB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 1p6hA-3l3pA:
undetectable
1p6hB-3l3pA:
undetectable		 1p6hA-3l3pA:
20.65
1p6hB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 1p6iA-3l3pA:
3.2
1p6iB-3l3pA:
undetectable		 1p6iA-3l3pA:
20.65
1p6iB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 1p6iA-3l3pA:
3.2
1p6iB-3l3pA:
undetectable		 1p6iA-3l3pA:
20.65
1p6iB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1p6jA-3l3pA:
undetectable
1p6jB-3l3pA:
undetectable		 1p6jA-3l3pA:
20.65
1p6jB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 1p6jA-3l3pA:
undetectable
1p6jB-3l3pA:
undetectable		 1p6jA-3l3pA:
20.65
1p6jB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 1p6kA-3l3pA:
3.2
1p6kB-3l3pA:
undetectable		 1p6kA-3l3pA:
20.65
1p6kB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 1p6kA-3l3pA:
3.2
1p6kB-3l3pA:
undetectable		 1p6kA-3l3pA:
20.65
1p6kB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3l3p IPAH9.8
(Shigella
flexneri) 		3 / 3 ASP A 291
LEU A 290
HIS A 279
 None
 0.74A 1qknA-3l3pA:
3.9		 1qknA-3l3pA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1rs6A-3l3pA:
undetectable
1rs6B-3l3pA:
3.3		 1rs6A-3l3pA:
20.65
1rs6B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.30A 1rs6A-3l3pA:
undetectable
1rs6B-3l3pA:
3.3		 1rs6A-3l3pA:
20.65
1rs6B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 1rs7A-3l3pA:
undetectable
1rs7B-3l3pA:
undetectable		 1rs7A-3l3pA:
20.65
1rs7B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.30A 1rs7A-3l3pA:
undetectable
1rs7B-3l3pA:
undetectable		 1rs7A-3l3pA:
20.65
1rs7B-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 LEU A 313
TRP A 274
LEU A 254
PHE A 327
 None
 1.31A 1ru9H-3l3pA:
undetectable
1ru9L-3l3pA:
undetectable		 1ru9H-3l3pA:
21.43
1ru9L-3l3pA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		5 / 9 LEU A 531
LEU A 370
VAL A 463
ALA A 462
PHE A 454
 None
 1.16A 1tbfA-3l3pA:
undetectable		 1tbfA-3l3pA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 1zvlA-3l3pA:
undetectable
1zvlB-3l3pA:
2.4		 1zvlA-3l3pA:
20.79
1zvlB-3l3pA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 1zzqA-3l3pA:
undetectable
1zzqB-3l3pA:
undetectable		 1zzqA-3l3pA:
20.65
1zzqB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 1zzqA-3l3pA:
undetectable
1zzqB-3l3pA:
undetectable		 1zzqA-3l3pA:
20.65
1zzqB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		5 / 9 THR A 366
LEU A 369
TYR A 523
LEU A 526
GLU A 519
 None
 1.19A 2azqA-3l3pA:
undetectable		 2azqA-3l3pA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 2g6hA-3l3pA:
undetectable
2g6hB-3l3pA:
undetectable		 2g6hA-3l3pA:
20.65
2g6hB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 2g6hA-3l3pA:
undetectable
2g6hB-3l3pA:
undetectable		 2g6hA-3l3pA:
20.65
2g6hB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 2g6kA-3l3pA:
undetectable
2g6kB-3l3pA:
undetectable		 2g6kA-3l3pA:
20.65
2g6kB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.29A 2g6kA-3l3pA:
undetectable
2g6kB-3l3pA:
undetectable		 2g6kA-3l3pA:
20.65
2g6kB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 2g6mA-3l3pA:
undetectable
2g6mB-3l3pA:
undetectable		 2g6mA-3l3pA:
20.65
2g6mB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 2g6mA-3l3pA:
undetectable
2g6mB-3l3pA:
undetectable		 2g6mA-3l3pA:
20.65
2g6mB-3l3pA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 2hx3A-3l3pA:
undetectable
2hx3B-3l3pA:
undetectable		 2hx3A-3l3pA:
20.60
2hx3B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 2hx4A-3l3pA:
undetectable
2hx4B-3l3pA:
undetectable		 2hx4A-3l3pA:
20.60
2hx4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 3b3mA-3l3pA:
2.2
3b3mB-3l3pA:
undetectable		 3b3mA-3l3pA:
20.60
3b3mB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.27A 3b3nA-3l3pA:
undetectable
3b3nB-3l3pA:
undetectable		 3b3nA-3l3pA:
20.60
3b3nB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 3b3nA-3l3pA:
undetectable
3b3nB-3l3pA:
undetectable		 3b3nA-3l3pA:
20.60
3b3nB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 3b3oA-3l3pA:
undetectable
3b3oB-3l3pA:
undetectable		 3b3oA-3l3pA:
20.60
3b3oB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 3b3oA-3l3pA:
undetectable
3b3oB-3l3pA:
undetectable		 3b3oA-3l3pA:
20.60
3b3oB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 3b3pA-3l3pA:
1.6
3b3pB-3l3pA:
3.2		 3b3pA-3l3pA:
20.60
3b3pB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 3b3pA-3l3pA:
undetectable
3b3pB-3l3pA:
3.2		 3b3pA-3l3pA:
20.60
3b3pB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 3fc5A-3l3pA:
undetectable
3fc5B-3l3pA:
3.8		 3fc5A-3l3pA:
20.60
3fc5B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.29A 3fc5A-3l3pA:
undetectable
3fc5B-3l3pA:
3.8		 3fc5A-3l3pA:
20.60
3fc5B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 3hsnA-3l3pA:
undetectable
3hsnB-3l3pA:
undetectable		 3hsnA-3l3pA:
20.60
3hsnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.26A 3hsnA-3l3pA:
undetectable
3hsnB-3l3pA:
undetectable		 3hsnA-3l3pA:
20.60
3hsnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 3hsoA-3l3pA:
undetectable
3hsoB-3l3pA:
undetectable		 3hsoA-3l3pA:
20.60
3hsoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.26A 3hsoA-3l3pA:
undetectable
3hsoB-3l3pA:
undetectable		 3hsoA-3l3pA:
20.60
3hsoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 3hspA-3l3pA:
undetectable
3hspB-3l3pA:
undetectable		 3hspA-3l3pA:
20.60
3hspB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.28A 3hspA-3l3pA:
undetectable
3hspB-3l3pA:
undetectable		 3hspA-3l3pA:
20.60
3hspB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 3jt4A-3l3pA:
3.1
3jt4B-3l3pA:
undetectable		 3jt4A-3l3pA:
20.60
3jt4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 3jt4A-3l3pA:
3.1
3jt4B-3l3pA:
undetectable		 3jt4A-3l3pA:
20.60
3jt4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 3jt5A-3l3pA:
undetectable
3jt5B-3l3pA:
undetectable		 3jt5A-3l3pA:
20.60
3jt5B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 3jt5A-3l3pA:
undetectable
3jt5B-3l3pA:
undetectable		 3jt5A-3l3pA:
20.60
3jt5B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 3jt7A-3l3pA:
undetectable
3jt7B-3l3pA:
undetectable		 3jt7A-3l3pA:
20.60
3jt7B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 3jt7A-3l3pA:
undetectable
3jt7B-3l3pA:
undetectable		 3jt7A-3l3pA:
20.60
3jt7B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 3jt8A-3l3pA:
undetectable
3jt8B-3l3pA:
3.3		 3jt8A-3l3pA:
20.60
3jt8B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 3jt8A-3l3pA:
undetectable
3jt8B-3l3pA:
undetectable		 3jt8A-3l3pA:
20.60
3jt8B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 3jt9A-3l3pA:
undetectable
3jt9B-3l3pA:
undetectable		 3jt9A-3l3pA:
20.60
3jt9B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 3jt9A-3l3pA:
undetectable
3jt9B-3l3pA:
undetectable		 3jt9A-3l3pA:
20.60
3jt9B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 3jtaA-3l3pA:
undetectable
3jtaB-3l3pA:
3.3		 3jtaA-3l3pA:
20.60
3jtaB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 3n2rA-3l3pA:
undetectable
3n2rB-3l3pA:
undetectable		 3n2rA-3l3pA:
20.60
3n2rB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 3n2rA-3l3pA:
undetectable
3n2rB-3l3pA:
undetectable		 3n2rA-3l3pA:
20.60
3n2rB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 309
VAL A 258
TRP A 261
PHE A 286
 None
 1.47A 3n61A-3l3pA:
3.1
3n61B-3l3pA:
3.3		 3n61A-3l3pA:
20.09
3n61B-3l3pA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 3nlwA-3l3pA:
undetectable
3nlwB-3l3pA:
undetectable		 3nlwA-3l3pA:
20.60
3nlwB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 3nm0A-3l3pA:
3.2
3nm0B-3l3pA:
undetectable		 3nm0A-3l3pA:
20.60
3nm0B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 GLU A 280
GLU A 281
PHE A 327
ALA A 283
 None
 1.07A 3pgyA-3l3pA:
undetectable
3pgyB-3l3pA:
undetectable		 3pgyA-3l3pA:
23.68
3pgyB-3l3pA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 3pnfA-3l3pA:
undetectable
3pnfB-3l3pA:
undetectable		 3pnfA-3l3pA:
20.60
3pnfB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 3q99A-3l3pA:
undetectable
3q99B-3l3pA:
undetectable		 3q99A-3l3pA:
20.60
3q99B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 3q99A-3l3pA:
undetectable
3q99B-3l3pA:
undetectable		 3q99A-3l3pA:
20.60
3q99B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 3q9aA-3l3pA:
undetectable
3q9aB-3l3pA:
undetectable		 3q9aA-3l3pA:
20.60
3q9aB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3l3p IPAH9.8
(Shigella
flexneri) 		3 / 3 HIS A 282
SER A 336
GLU A 335
 None
 0.70A 3s8pA-3l3pA:
undetectable		 3s8pA-3l3pA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 3tylA-3l3pA:
undetectable
3tylB-3l3pA:
undetectable		 3tylA-3l3pA:
20.60
3tylB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 3tylA-3l3pA:
undetectable
3tylB-3l3pA:
undetectable		 3tylA-3l3pA:
20.60
3tylB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 3tymA-3l3pA:
3.0
3tymB-3l3pA:
undetectable		 3tymA-3l3pA:
20.60
3tymB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 3tynA-3l3pA:
undetectable
3tynB-3l3pA:
undetectable		 3tynA-3l3pA:
20.60
3tynB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 PHE A 362
PRO A 459
GLY A 373
PHE A 454
 None
 1.09A 3tzfB-3l3pA:
undetectable		 3tzfB-3l3pA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 3ufuA-3l3pA:
undetectable
3ufuB-3l3pA:
undetectable		 3ufuA-3l3pA:
20.60
3ufuB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.35A 3ufwA-3l3pA:
3.2
3ufwB-3l3pA:
undetectable		 3ufwA-3l3pA:
20.60
3ufwB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		3 / 3 ARG A 490
GLU A 517
THR A 518
 None
 0.86A 3v4tA-3l3pA:
undetectable		 3v4tA-3l3pA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4caqA-3l3pA:
undetectable
4caqB-3l3pA:
3.1		 4caqA-3l3pA:
20.60
4caqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4caqA-3l3pA:
undetectable
4caqB-3l3pA:
undetectable		 4caqA-3l3pA:
20.60
4caqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 4ctpA-3l3pA:
undetectable
4ctpB-3l3pA:
undetectable		 4ctpA-3l3pA:
20.60
4ctpB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 4ctqA-3l3pA:
3.1
4ctqB-3l3pA:
undetectable		 4ctqA-3l3pA:
20.60
4ctqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.36A 4ctqA-3l3pA:
3.1
4ctqB-3l3pA:
undetectable		 4ctqA-3l3pA:
20.60
4ctqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4ctxA-3l3pA:
3.1
4ctxB-3l3pA:
undetectable		 4ctxA-3l3pA:
20.60
4ctxB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 4cx6A-3l3pA:
undetectable
4cx6B-3l3pA:
undetectable		 4cx6A-3l3pA:
20.60
4cx6B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.36A 4cx6A-3l3pA:
undetectable
4cx6B-3l3pA:
undetectable		 4cx6A-3l3pA:
20.60
4cx6B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4d1nA-3l3pA:
undetectable
4d1nB-3l3pA:
undetectable		 4d1nA-3l3pA:
21.61
4d1nB-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 4d1nA-3l3pA:
undetectable
4d1nB-3l3pA:
undetectable		 4d1nA-3l3pA:
21.61
4d1nB-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4d1nC-3l3pA:
undetectable
4d1nD-3l3pA:
undetectable		 4d1nC-3l3pA:
21.61
4d1nD-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4d1nC-3l3pA:
undetectable
4d1nD-3l3pA:
undetectable		 4d1nC-3l3pA:
21.61
4d1nD-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4d2yA-3l3pA:
undetectable
4d2yB-3l3pA:
undetectable		 4d2yA-3l3pA:
20.60
4d2yB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 4d30A-3l3pA:
undetectable
4d30B-3l3pA:
undetectable		 4d30A-3l3pA:
20.60
4d30B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4d31A-3l3pA:
undetectable
4d31B-3l3pA:
undetectable		 4d31A-3l3pA:
20.60
4d31B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4d31A-3l3pA:
undetectable
4d31B-3l3pA:
undetectable		 4d31A-3l3pA:
20.60
4d31B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 4d3bA-3l3pA:
undetectable
4d3bB-3l3pA:
undetectable		 4d3bA-3l3pA:
20.60
4d3bB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4d7oA-3l3pA:
undetectable
4d7oB-3l3pA:
3.3		 4d7oA-3l3pA:
20.60
4d7oB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4d7oA-3l3pA:
undetectable
4d7oB-3l3pA:
3.3		 4d7oA-3l3pA:
20.60
4d7oB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4euxA-3l3pA:
undetectable
4euxB-3l3pA:
3.3		 4euxA-3l3pA:
20.60
4euxB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4fvwA-3l3pA:
undetectable
4fvwB-3l3pA:
undetectable		 4fvwA-3l3pA:
20.60
4fvwB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4fvwA-3l3pA:
undetectable
4fvwB-3l3pA:
undetectable		 4fvwA-3l3pA:
20.60
4fvwB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.35A 4fvxA-3l3pA:
undetectable
4fvxB-3l3pA:
undetectable		 4fvxA-3l3pA:
20.60
4fvxB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 4fvyA-3l3pA:
undetectable
4fvyB-3l3pA:
undetectable		 4fvyA-3l3pA:
20.60
4fvyB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 4fvyA-3l3pA:
undetectable
4fvyB-3l3pA:
undetectable		 4fvyA-3l3pA:
20.60
4fvyB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.40A 4fvzA-3l3pA:
undetectable
4fvzB-3l3pA:
undetectable		 4fvzA-3l3pA:
20.60
4fvzB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4fw0A-3l3pA:
undetectable
4fw0B-3l3pA:
undetectable		 4fw0A-3l3pA:
20.60
4fw0B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4fw0A-3l3pA:
undetectable
4fw0B-3l3pA:
undetectable		 4fw0A-3l3pA:
20.60
4fw0B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4gqeA-3l3pA:
undetectable
4gqeB-3l3pA:
undetectable		 4gqeA-3l3pA:
20.60
4gqeB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4gqeA-3l3pA:
undetectable
4gqeB-3l3pA:
undetectable		 4gqeA-3l3pA:
20.60
4gqeB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4jsjA-3l3pA:
undetectable
4jsjB-3l3pA:
3.0		 4jsjA-3l3pA:
20.60
4jsjB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.36A 4jsjA-3l3pA:
undetectable
4jsjB-3l3pA:
3.1		 4jsjA-3l3pA:
20.60
4jsjB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4k5eA-3l3pA:
undetectable
4k5eB-3l3pA:
undetectable		 4k5eA-3l3pA:
20.60
4k5eB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 4k5eA-3l3pA:
undetectable
4k5eB-3l3pA:
undetectable		 4k5eA-3l3pA:
20.60
4k5eB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4k5gA-3l3pA:
3.1
4k5gB-3l3pA:
undetectable		 4k5gA-3l3pA:
20.60
4k5gB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.36A 4k5gA-3l3pA:
undetectable
4k5gB-3l3pA:
undetectable		 4k5gA-3l3pA:
20.60
4k5gB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4kchA-3l3pA:
undetectable
4kchB-3l3pA:
undetectable		 4kchA-3l3pA:
20.60
4kchB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 4kcjA-3l3pA:
undetectable
4kcjB-3l3pA:
undetectable		 4kcjA-3l3pA:
20.60
4kcjB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 4kclA-3l3pA:
undetectable
4kclB-3l3pA:
3.3		 4kclA-3l3pA:
20.60
4kclB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 4kclA-3l3pA:
undetectable
4kclB-3l3pA:
3.3		 4kclA-3l3pA:
20.60
4kclB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4kcmA-3l3pA:
undetectable
4kcmB-3l3pA:
undetectable		 4kcmA-3l3pA:
20.60
4kcmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 4kcmA-3l3pA:
undetectable
4kcmB-3l3pA:
undetectable		 4kcmA-3l3pA:
20.60
4kcmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.35A 4kcnA-3l3pA:
undetectable
4kcnB-3l3pA:
3.2		 4kcnA-3l3pA:
20.60
4kcnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.39A 4kcnA-3l3pA:
undetectable
4kcnB-3l3pA:
undetectable		 4kcnA-3l3pA:
20.60
4kcnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4kcoA-3l3pA:
3.3
4kcoB-3l3pA:
undetectable		 4kcoA-3l3pA:
20.60
4kcoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4kcoA-3l3pA:
3.3
4kcoB-3l3pA:
undetectable		 4kcoA-3l3pA:
20.60
4kcoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 4luxA-3l3pA:
3.1
4luxB-3l3pA:
undetectable		 4luxA-3l3pA:
20.60
4luxB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 4uchA-3l3pA:
3.1
4uchB-3l3pA:
undetectable		 4uchA-3l3pA:
21.43
4uchB-3l3pA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4uchA-3l3pA:
3.1
4uchB-3l3pA:
undetectable		 4uchA-3l3pA:
21.43
4uchB-3l3pA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 4uh1A-3l3pA:
undetectable
4uh1B-3l3pA:
undetectable		 4uh1A-3l3pA:
20.60
4uh1B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4uh1A-3l3pA:
undetectable
4uh1B-3l3pA:
undetectable		 4uh1A-3l3pA:
20.60
4uh1B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.38A 4uh4A-3l3pA:
undetectable
4uh4B-3l3pA:
undetectable		 4uh4A-3l3pA:
20.60
4uh4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4uh4A-3l3pA:
undetectable
4uh4B-3l3pA:
undetectable		 4uh4A-3l3pA:
20.60
4uh4B-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 4uh5A-3l3pA:
3.1
4uh5B-3l3pA:
undetectable		 4uh5A-3l3pA:
21.48
4uh5B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 4uh5A-3l3pA:
3.1
4uh5B-3l3pA:
undetectable		 4uh5A-3l3pA:
21.48
4uh5B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4uh6A-3l3pA:
undetectable
4uh6B-3l3pA:
3.1		 4uh6A-3l3pA:
21.48
4uh6B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 4upmA-3l3pA:
undetectable
4upmB-3l3pA:
3.3		 4upmA-3l3pA:
20.60
4upmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 4upmA-3l3pA:
undetectable
4upmB-3l3pA:
3.3		 4upmA-3l3pA:
20.60
4upmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4upoA-3l3pA:
undetectable
4upoB-3l3pA:
undetectable		 4upoA-3l3pA:
20.60
4upoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4upoA-3l3pA:
undetectable
4upoB-3l3pA:
undetectable		 4upoA-3l3pA:
20.60
4upoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 4v3uA-3l3pA:
3.1
4v3uB-3l3pA:
undetectable		 4v3uA-3l3pA:
21.61
4v3uB-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4v3uA-3l3pA:
3.1
4v3uB-3l3pA:
undetectable		 4v3uA-3l3pA:
21.61
4v3uB-3l3pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 4v3xA-3l3pA:
undetectable
4v3xB-3l3pA:
undetectable		 4v3xA-3l3pA:
20.60
4v3xB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 8 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 4v3yA-3l3pA:
undetectable
4v3yB-3l3pA:
undetectable		 4v3yA-3l3pA:
20.60
4v3yB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 4v3zA-3l3pA:
undetectable
4v3zB-3l3pA:
undetectable		 4v3zA-3l3pA:
20.60
4v3zB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 5adcA-3l3pA:
undetectable
5adcB-3l3pA:
undetectable		 5adcA-3l3pA:
20.60
5adcB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.35A 5adgA-3l3pA:
undetectable
5adgB-3l3pA:
undetectable		 5adgA-3l3pA:
21.48
5adgB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 5aglA-3l3pA:
undetectable
5aglB-3l3pA:
undetectable		 5aglA-3l3pA:
20.60
5aglB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 5aglA-3l3pA:
undetectable
5aglB-3l3pA:
undetectable		 5aglA-3l3pA:
20.60
5aglB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 5agmA-3l3pA:
undetectable
5agmB-3l3pA:
undetectable		 5agmA-3l3pA:
20.60
5agmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 5agmA-3l3pA:
undetectable
5agmB-3l3pA:
undetectable		 5agmA-3l3pA:
20.60
5agmB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 5agnA-3l3pA:
undetectable
5agnB-3l3pA:
undetectable		 5agnA-3l3pA:
20.60
5agnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 5agnA-3l3pA:
undetectable
5agnB-3l3pA:
undetectable		 5agnA-3l3pA:
20.60
5agnB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.37A 5agoA-3l3pA:
undetectable
5agoB-3l3pA:
undetectable		 5agoA-3l3pA:
20.60
5agoB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 5fvqA-3l3pA:
undetectable
5fvqB-3l3pA:
undetectable		 5fvqA-3l3pA:
20.60
5fvqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 5fvqA-3l3pA:
undetectable
5fvqB-3l3pA:
undetectable		 5fvqA-3l3pA:
20.60
5fvqB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 5fvrA-3l3pA:
undetectable
5fvrB-3l3pA:
undetectable		 5fvrA-3l3pA:
20.60
5fvrB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 5fvrA-3l3pA:
undetectable
5fvrB-3l3pA:
undetectable		 5fvrA-3l3pA:
20.60
5fvrB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 5fvsA-3l3pA:
undetectable
5fvsB-3l3pA:
undetectable		 5fvsA-3l3pA:
20.60
5fvsB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 5fvsA-3l3pA:
undetectable
5fvsB-3l3pA:
undetectable		 5fvsA-3l3pA:
20.60
5fvsB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 5fvtA-3l3pA:
undetectable
5fvtB-3l3pA:
undetectable		 5fvtA-3l3pA:
20.60
5fvtB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 5fvtA-3l3pA:
undetectable
5fvtB-3l3pA:
undetectable		 5fvtA-3l3pA:
20.60
5fvtB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 6 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.26A 5fvuA-3l3pA:
undetectable
5fvuB-3l3pA:
3.2		 5fvuA-3l3pA:
21.48
5fvuB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.31A 5fvuA-3l3pA:
undetectable
5fvuB-3l3pA:
3.3		 5fvuA-3l3pA:
21.48
5fvuB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.28A 5fvvA-3l3pA:
undetectable
5fvvB-3l3pA:
2.6		 5fvvA-3l3pA:
21.48
5fvvB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.30A 5fvvA-3l3pA:
3.2
5fvvB-3l3pA:
2.6		 5fvvA-3l3pA:
21.48
5fvvB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 5fvwA-3l3pA:
3.3
5fvwB-3l3pA:
2.6		 5fvwA-3l3pA:
21.48
5fvwB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 5fvwA-3l3pA:
3.3
5fvwB-3l3pA:
2.6		 5fvwA-3l3pA:
21.48
5fvwB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 5fvxA-3l3pA:
3.0
5fvxB-3l3pA:
3.2		 5fvxA-3l3pA:
21.48
5fvxB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 5g0nA-3l3pA:
undetectable
5g0nB-3l3pA:
undetectable		 5g0nA-3l3pA:
20.60
5g0nB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 5g0nA-3l3pA:
undetectable
5g0nB-3l3pA:
undetectable		 5g0nA-3l3pA:
20.60
5g0nB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3l3p IPAH9.8
(Shigella
flexneri) 		5 / 12 ALA A 510
GLY A 511
ASN A 485
GLU A 481
LEU A 483
 None
 1.03A 5nwuA-3l3pA:
undetectable		 5nwuA-3l3pA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 5uo1A-3l3pA:
undetectable
5uo1B-3l3pA:
undetectable		 5uo1A-3l3pA:
21.48
5uo1B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 5uo4A-3l3pA:
3.1
5uo4B-3l3pA:
undetectable		 5uo4A-3l3pA:
21.48
5uo4B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 5uo5A-3l3pA:
3.1
5uo5B-3l3pA:
undetectable		 5uo5A-3l3pA:
21.48
5uo5B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 5vunA-3l3pA:
undetectable
5vunB-3l3pA:
undetectable		 5vunA-3l3pA:
20.60
5vunB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.36A 5vunA-3l3pA:
undetectable
5vunB-3l3pA:
undetectable		 5vunA-3l3pA:
20.60
5vunB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.35A 5vutA-3l3pA:
undetectable
5vutB-3l3pA:
undetectable		 5vutA-3l3pA:
20.60
5vutB-3l3pA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 5vuwA-3l3pA:
3.2
5vuwB-3l3pA:
undetectable		 5vuwA-3l3pA:
21.48
5vuwB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 5vuxA-3l3pA:
3.0
5vuxB-3l3pA:
undetectable		 5vuxA-3l3pA:
21.48
5vuxB-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.37A 5vv2A-3l3pA:
3.4
5vv2B-3l3pA:
3.7		 5vv2A-3l3pA:
21.48
5vv2B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 5vv5A-3l3pA:
undetectable
5vv5B-3l3pA:
undetectable		 5vv5A-3l3pA:
21.48
5vv5B-3l3pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 6aurA-3l3pA:
undetectable
6aurB-3l3pA:
undetectable		 6aurA-3l3pA:
12.03
6aurB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 6aurA-3l3pA:
undetectable
6aurB-3l3pA:
undetectable		 6aurA-3l3pA:
12.03
6aurB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 6ausA-3l3pA:
undetectable
6ausB-3l3pA:
undetectable		 6ausA-3l3pA:
12.03
6ausB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 6ausA-3l3pA:
undetectable
6ausB-3l3pA:
undetectable		 6ausA-3l3pA:
12.03
6ausB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.34A 6autA-3l3pA:
undetectable
6autB-3l3pA:
undetectable		 6autA-3l3pA:
12.03
6autB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 6auvA-3l3pA:
3.1
6auvB-3l3pA:
3.3		 6auvA-3l3pA:
12.03
6auvB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.35A 6auvA-3l3pA:
3.1
6auvB-3l3pA:
3.3		 6auvA-3l3pA:
12.03
6auvB-3l3pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 6auyA-3l3pA:
3.3
6auyB-3l3pA:
3.7		 6auyA-3l3pA:
12.59
6auyB-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 6auzA-3l3pA:
3.3
6auzB-3l3pA:
2.7		 6auzA-3l3pA:
12.59
6auzB-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.31A 6av0A-3l3pA:
3.0
6av0B-3l3pA:
3.4		 6av0A-3l3pA:
12.59
6av0B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.32A 6av1A-3l3pA:
undetectable
6av1B-3l3pA:
undetectable		 6av1A-3l3pA:
12.59
6av1B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.36A 6av2A-3l3pA:
undetectable
6av2B-3l3pA:
undetectable		 6av2A-3l3pA:
12.59
6av2B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.29A 6av3A-3l3pA:
3.2
6av3B-3l3pA:
undetectable		 6av3A-3l3pA:
12.59
6av3B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.33A 6av3A-3l3pA:
3.2
6av3B-3l3pA:
undetectable		 6av3A-3l3pA:
12.59
6av3B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 6av4A-3l3pA:
undetectable
6av4B-3l3pA:
undetectable		 6av4A-3l3pA:
12.59
6av4B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.34A 6av4A-3l3pA:
undetectable
6av4B-3l3pA:
undetectable		 6av4A-3l3pA:
12.59
6av4B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.33A 6av5A-3l3pA:
undetectable
6av5B-3l3pA:
undetectable		 6av5A-3l3pA:
12.59
6av5B-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 6cicA-3l3pA:
3.2
6cicB-3l3pA:
undetectable		 6cicA-3l3pA:
12.59
6cicB-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 6cicA-3l3pA:
3.2
6cicB-3l3pA:
undetectable		 6cicA-3l3pA:
12.59
6cicB-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 VAL A 258
TRP A 261
TRP A 274
GLU A 314
 None
 1.30A 6cidA-3l3pA:
undetectable
6cidB-3l3pA:
undetectable		 6cidA-3l3pA:
12.59
6cidB-3l3pA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3l3p IPAH9.8
(Shigella
flexneri) 		4 / 7 TRP A 274
GLU A 314
VAL A 258
TRP A 261
 None
 1.32A 6cidA-3l3pA:
undetectable
6cidB-3l3pA:
undetectable		 6cidA-3l3pA:
12.59
6cidB-3l3pA:
12.59