SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_0 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	3l40	BRCT-CONTAINING PROTEIN 1 (Schizosaccharomy ces pombe)	4 / 4	THR A 708 LEU A 712 LEU A 771 GLN A 767	None	1.13A	1fbmA-3l40A: undetectable	1fbmA-3l40A: 12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZV_A_AZMA263_1 (CARBONIC ANHYDRASE 13)	3l40	BRCT-CONTAINING PROTEIN 1 (Schizosaccharomy ces pombe)	5 / 12	VAL A 777 VAL A 823 LEU A 855 THR A 858 VAL A 859	None	1.00A	3czvA-3l40A: undetectable 3czvB-3l40A: undetectable	3czvA-3l40A: 22.78 3czvB-3l40A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZV_B_AZMB263_1 (CARBONIC ANHYDRASE 13)	3l40	BRCT-CONTAINING PROTEIN 1 (Schizosaccharomy ces pombe)	5 / 10	VAL A 777 VAL A 823 LEU A 855 THR A 858 VAL A 859	None	0.96A	3czvB-3l40A: undetectable	3czvB-3l40A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BMV_C_VLBC507_1 (TUBULIN BETA CHAIN TUBULIN ALPHA-1B CHAIN)	3l40	BRCT-CONTAINING PROTEIN 1 (Schizosaccharomy ces pombe)	4 / 6	ASP A 819 TYR A 809 TYR A 778 LEU A 806	None	1.31A	5bmvB-3l40A: undetectable	5bmvB-3l40A: 18.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FBM_B_RTLB951_0","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","3l40","BRCT-CONTAINING PROTEIN 1","Schizosaccharomyces pombe",4,"THR A 708;LEU A 712;LEU A 771;GLN A 767","None","1.13A","1fbmA-3l40A:undetectable","1fbmA-3l40A:12.56"],["3CZV_A_AZMA263_1","CARBONIC ANHYDRASE 13;CARBONIC ANHYDRASE 13","3l40","BRCT-CONTAINING PROTEIN 1","Schizosaccharomyces pombe",5,"VAL A 777;VAL A 823;LEU A 855;THR A 858;VAL A 859","None","1.00A","3czvA-3l40A:undetectable;3czvB-3l40A:undetectable","3czvA-3l40A:22.78;3czvB-3l40A:22.78"],["3CZV_B_AZMB263_1","CARBONIC ANHYDRASE 13","3l40","BRCT-CONTAINING PROTEIN 1","Schizosaccharomyces pombe",5,"VAL A 777;VAL A 823;LEU A 855;THR A 858;VAL A 859","None","0.96A","3czvB-3l40A:undetectable","3czvB-3l40A:22.78"],["5BMV_C_VLBC507_1","TUBULIN BETA CHAIN;TUBULIN ALPHA-1B CHAIN","3l40","BRCT-CONTAINING PROTEIN 1","Schizosaccharomyces pombe",4,"ASP A 819;TYR A 809;TYR A 778;LEU A 806","None","1.31A","5bmvB-3l40A:undetectable","5bmvB-3l40A:18.51"]]