SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3l43 DYNAMIN-3
(Homo
sapiens) 		4 / 6 LEU A 122
GLU A 100
THR A 105
LEU A  71
 None
 1.16A 1etb2-3l43A:
undetectable		 1etb2-3l43A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3l43 DYNAMIN-3
(Homo
sapiens) 		5 / 9 LEU A 281
LEU A 132
ILE A 135
THR A 200
ILE A 171
 None
 1.21A 1hzeA-3l43A:
undetectable
1hzeB-3l43A:
undetectable		 1hzeA-3l43A:
16.40
1hzeB-3l43A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3l43 DYNAMIN-3
(Homo
sapiens) 		5 / 9 THR A 200
ILE A 171
LEU A 281
LEU A 132
ILE A 135
 None
 1.21A 1hzeA-3l43A:
undetectable
1hzeB-3l43A:
undetectable		 1hzeA-3l43A:
16.40
1hzeB-3l43A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IEO_A_AMJA300_0
(CARBONIC ANHYDRASE 2)		 3l43 DYNAMIN-3
(Homo
sapiens) 		4 / 4 ILE A 135
GLN A  33
VAL A  70
PHE A 163
 None
 1.26A 3ieoA-3l43A:
undetectable		 3ieoA-3l43A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3l43 DYNAMIN-3
(Homo
sapiens) 		4 / 5 HIS A 128
THR A  75
GLU A  79
ASP A  93
 None
 1.28A 3tm4A-3l43A:
undetectable		 3tm4A-3l43A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3l43 DYNAMIN-3
(Homo
sapiens) 		4 / 5 HIS A 128
THR A  75
GLU A  79
ASP A  93
 None
 1.30A 3tm4B-3l43A:
undetectable		 3tm4B-3l43A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3l43 DYNAMIN-3
(Homo
sapiens) 		4 / 7 VAL A 124
ALA A  81
LEU A  71
LEU A  69
 None
 0.56A 5jq7A-3l43A:
undetectable		 5jq7A-3l43A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3l43 DYNAMIN-3
(Homo
sapiens) 		5 / 12 VAL A  36
VAL A 234
LEU A 277
PHE A  51
LEU A 134
 None
 1.39A 6a7pB-3l43A:
undetectable		 6a7pB-3l43A:
18.78