SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 11 ALA A 123
ILE A 287
VAL A 117
LEU A 207
ALA A 205
 None
 1.15A 1rv7A-3l44A:
undetectable
1rv7B-3l44A:
undetectable		 1rv7A-3l44A:
14.91
1rv7B-3l44A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 11 ALA A 205
PRO A 263
LEU A 153
THR A 121
VAL A 154
 None
None
None
LLP  A 270 ( 3.5A)
None
 1.18A 1rv7A-3l44A:
undetectable
1rv7B-3l44A:
undetectable		 1rv7A-3l44A:
14.91
1rv7B-3l44A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		3 / 3 GLU A 414
GLU A 421
LEU A 336
 None
 0.72A 1v8bA-3l44A:
2.0		 1v8bA-3l44A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 THR A  69
ILE A 314
GLY A 313
GLY A 273
ILE A  76
 None
None
None
LLP  A 270 ( 4.0A)
None
 1.01A 1vq1B-3l44A:
3.1		 1vq1B-3l44A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 ILE A 351
LEU A 397
PHE A 383
PHE A 364
LEU A 430
 None
 1.30A 2w3mB-3l44A:
undetectable		 2w3mB-3l44A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 8 GLY A 313
GLY A 273
GLY A 275
ILE A  67
THR A  69
 None
LLP  A 270 ( 4.0A)
None
None
None
 1.29A 3d41A-3l44A:
undetectable		 3d41A-3l44A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 11 GLY A 358
ALA A 359
ILE A 245
LEU A 258
ILE A 217
 None
None
LLP  A 270 ( 4.2A)
None
None
 0.87A 3em4A-3l44A:
undetectable		 3em4A-3l44A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		3 / 3 GLU A 286
ASP A 112
ASP A 264
 None
 0.77A 3jb2A-3l44A:
undetectable		 3jb2A-3l44A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 GLY A 275
GLY A 274
ALA A 315
PRO A 277
ALA A  72
 None
 0.89A 3jb2A-3l44A:
undetectable		 3jb2A-3l44A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		3 / 3 SER A 119
GLY A 120
THR A 121
 LLP  A 270 ( 3.9A)
LLP  A 270 ( 3.2A)
LLP  A 270 ( 3.5A)
 0.17A 3k9wA-3l44A:
undetectable		 3k9wA-3l44A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 8 ASN A 367
GLU A 370
ILE A 369
ASP A 371
 None
 0.96A 4d33A-3l44A:
undetectable		 4d33A-3l44A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ASN A 367
GLU A 370
ILE A 369
ASP A 371
 None
 1.03A 4d33B-3l44A:
undetectable		 4d33B-3l44A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 8 ASN A 367
GLU A 370
ILE A 369
ASP A 371
 None
 1.11A 4d39A-3l44A:
undetectable		 4d39A-3l44A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ASN A 367
GLU A 370
ILE A 369
ASP A 371
 None
 1.01A 4d39B-3l44A:
undetectable		 4d39B-3l44A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 GLY A 273
GLY A 274
ASN A 118
PRO A 307
LEU A  89
 LLP  A 270 ( 4.0A)
None
None
None
None
 0.96A 4fp9A-3l44A:
undetectable		 4fp9A-3l44A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 GLY A 273
GLY A 274
ASN A 118
PRO A 307
LEU A  89
 LLP  A 270 ( 4.0A)
None
None
None
None
 0.94A 4fp9C-3l44A:
undetectable		 4fp9C-3l44A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 GLY A 273
GLY A 274
ASN A 118
PRO A 307
LEU A  89
 LLP  A 270 ( 4.0A)
None
None
None
None
 0.96A 4fp9D-3l44A:
undetectable		 4fp9D-3l44A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 11 GLY A  22
GLY A  21
ALA A  15
LEU A  16
HIS A  18
 None
 1.11A 4l8fB-3l44A:
2.1		 4l8fB-3l44A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 11 GLY A  22
GLY A  21
ALA A  15
LEU A  16
HIS A  18
 None
 1.14A 4l8fD-3l44A:
2.1		 4l8fD-3l44A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 GLY A 273
GLY A 313
ALA A  79
ASN A 306
GLY A 305
 LLP  A 270 ( 4.0A)
None
None
None
None
 0.81A 4n09D-3l44A:
undetectable		 4n09D-3l44A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ILE A 245
GLU A 403
GLY A 216
GLY A 213
 LLP  A 270 ( 4.2A)
None
None
None
 0.87A 5a06A-3l44A:
undetectable		 5a06A-3l44A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ILE A 245
GLU A 403
GLY A 216
GLY A 213
 LLP  A 270 ( 4.2A)
None
None
None
 0.86A 5a06E-3l44A:
undetectable		 5a06E-3l44A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ILE A 245
GLU A 403
GLY A 216
GLY A 213
 LLP  A 270 ( 4.2A)
None
None
None
 0.86A 5a06F-3l44A:
3.0		 5a06F-3l44A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ALA A  62
GLY A 333
GLU A 337
ARG A 249
 None
 1.01A 5btdA-3l44A:
undetectable
5btdB-3l44A:
undetectable
5btdC-3l44A:
undetectable		 5btdA-3l44A:
23.60
5btdB-3l44A:
21.43
5btdC-3l44A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 7 ARG A 249
ALA A  62
GLY A 333
GLU A 337
 None
 1.02A 5btdA-3l44A:
undetectable
5btdC-3l44A:
undetectable
5btdD-3l44A:
undetectable		 5btdA-3l44A:
23.60
5btdC-3l44A:
23.60
5btdD-3l44A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 PHE A 386
LEU A 360
LEU A 353
PHE A 427
THR A 419
 None
 1.15A 5ieoA-3l44A:
undetectable		 5ieoA-3l44A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 PHE A 386
LEU A 360
LEU A 353
PHE A 427
THR A 419
 None
 1.15A 5iepA-3l44A:
undetectable		 5iepA-3l44A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 6 ILE A 128
GLY A 283
MET A 288
ILE A 240
 None
 1.00A 5j4nB-3l44A:
undetectable		 5j4nB-3l44A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 PHE A  30
LEU A  11
ILE A  19
LEU A 391
TYR A  57
 None
 1.29A 5ycpA-3l44A:
undetectable		 5ycpA-3l44A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		5 / 12 ILE A  76
ALA A  79
ALA A 311
ILE A  67
HIS A  71
 None
 1.01A 6a60D-3l44A:
undetectable		 6a60D-3l44A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 5 GLU A 209
HIS A 148
LEU A 155
VAL A 154
 LLP  A 270 ( 3.9A)
None
None
None
 0.99A 6bc9A-3l44A:
undetectable		 6bc9A-3l44A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 6 GLY A 333
LEU A 332
VAL A 362
PHE A 427
 None
 0.86A 6h7lA-3l44A:
undetectable		 6h7lA-3l44A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1
(Bacillus
anthracis) 		4 / 6 GLY A 333
LEU A 332
VAL A 362
PHE A 427
 None
 0.87A 6h7lB-3l44A:
undetectable		 6h7lB-3l44A:
12.00