SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4
(Mus
musculus) 		5 / 10 LYS B 596
VAL B 597
ILE B 601
ILE B 610
PHE B 666
 None
 1.12A 3kz7A-3l51B:
undetectable		 3kz7A-3l51B:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
(Mus
musculus) 		5 / 9 GLU A 542
ALA A 545
ILE A 530
VAL A 532
ALA A 606
 None
 1.06A 4lbgB-3l51A:
undetectable		 4lbgB-3l51A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
(Mus
musculus) 		5 / 12 VAL A 598
HIS A 604
ALA A 636
LEU A 652
ASN A 631
 None
 1.41A 4qdcA-3l51A:
undetectable		 4qdcA-3l51A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
(Mus
musculus) 		5 / 10 VAL A 650
VAL A 629
LEU A 541
THR A 537
ALA A 538
 None
 1.34A 4yhaB-3l51A:
undetectable		 4yhaB-3l51A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4
(Mus
musculus) 		4 / 6 GLY B 612
PRO B 611
THR B 648
GLU B 651
 None
 1.04A 5ny7A-3l51B:
undetectable		 5ny7A-3l51B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
(Mus
musculus) 		5 / 9 VAL A 650
VAL A 629
LEU A 541
THR A 537
ALA A 538
 None
 1.37A 5tt3E-3l51A:
undetectable		 5tt3E-3l51A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4
(Mus
musculus) 		4 / 4 TYR B 707
ARG B 711
THR B 713
LEU B 714
 GOL  B 403 (-4.4A)
GOL  B 403 (-3.8A)
None
None
 1.08A 5x19W-3l51B:
0.0		 5x19W-3l51B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4
(Mus
musculus) 		4 / 5 TYR B 707
ARG B 711
THR B 713
LEU B 714
 GOL  B 403 (-4.4A)
GOL  B 403 (-3.8A)
None
None
 1.19A 5x1bJ-3l51B:
undetectable		 5x1bJ-3l51B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
(Mus
musculus) 		3 / 3 THR A 651
ALA A 636
LYS A 638
 None
 0.77A 6fgcA-3l51A:
undetectable		 6fgcA-3l51A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4
(Mus
musculus) 		4 / 5 TYR B 707
ARG B 711
THR B 713
LEU B 714
 GOL  B 403 (-4.4A)
GOL  B 403 (-3.8A)
None
None
 1.02A 6nknW-3l51B:
undetectable		 6nknW-3l51B:
16.27