SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_B_SAMB298_1 (PUTATIVE MODIFICATION METHYLASE)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	3 / 3	ASP A 102 THR A 34 GLU A 150	None EDO A 303 (-4.7A) None	0.79A	2zifB-3l57A: undetectable	2zifB-3l57A: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHX_B_PXLB313_1 (PYRIDOXAL KINASE)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	4 / 8	VAL A 117 HIS A 162 THR A 161 VAL A 16	None MN3 A 300 ( 3.3A) None None	0.69A	3fhxB-3l57A: undetectable	3fhxB-3l57A: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Z_A_FLPA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	5 / 12	VAL A 93 TYR A 208 LEU A 210 ALA A 108 LEU A 199	None None EDO A 317 ( 4.1A) EDO A 305 (-3.7A) None	1.05A	3n8zA-3l57A: 1.5	3n8zA-3l57A: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA0_A_SHHA404_1 (HISTONE DEACETYLASE 8)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	5 / 12	TYR A 83 HIS A 149 HIS A 162 PHE A 164 GLY A 17	None MN3 A 300 (-3.2A) MN3 A 300 ( 3.3A) None None	1.07A	4qa0A-3l57A: undetectable	4qa0A-3l57A: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA0_B_SHHB404_2 (HISTONE DEACETYLASE 8)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	5 / 11	TYR A 83 HIS A 149 HIS A 162 PHE A 164 GLY A 17	None MN3 A 300 (-3.2A) MN3 A 300 ( 3.3A) None None	1.07A	4qa0B-3l57A: undetectable	4qa0B-3l57A: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA2_A_SHHA404_1 (HISTONE DEACETYLASE 8)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	5 / 12	TYR A 83 HIS A 149 HIS A 162 PHE A 164 GLY A 17	None MN3 A 300 (-3.2A) MN3 A 300 ( 3.3A) None None	1.06A	4qa2A-3l57A: undetectable	4qa2A-3l57A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA2_B_SHHB404_1 (HISTONE DEACETYLASE 8)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	5 / 12	TYR A 83 HIS A 149 HIS A 162 PHE A 164 GLY A 17	None MN3 A 300 (-3.2A) MN3 A 300 ( 3.3A) None None	1.08A	4qa2B-3l57A: undetectable	4qa2B-3l57A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	3l57	MOBILIZATION PROTEIN TRAI (Escherichia coli)	3 / 3	ALA A 206 GLN A 96 THR A 104	EDO A 306 ( 3.8A) None EDO A 305 (-4.3A)	0.69A	5n0oA-3l57A: undetectable	5n0oA-3l57A: 22.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZIF_B_SAMB298_1","PUTATIVE MODIFICATION METHYLASE","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",3,"ASP A 102;THR A  34;GLU A 150","None;EDO A 303 (-4.7A);None","0.79A","2zifB-3l57A:undetectable","2zifB-3l57A:21.04"],["3FHX_B_PXLB313_1","PYRIDOXAL KINASE","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",4,"VAL A 117;HIS A 162;THR A 161;VAL A  16","None;MN3 A 300 ( 3.3A);None;None","0.69A","3fhxB-3l57A:undetectable","3fhxB-3l57A:21.47"],["3N8Z_A_FLPA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",5,"VAL A  93;TYR A 208;LEU A 210;ALA A 108;LEU A 199","None;None;EDO A 317 ( 4.1A);EDO A 305 (-3.7A);None","1.05A","3n8zA-3l57A:1.5","3n8zA-3l57A:18.80"],["4QA0_A_SHHA404_1","HISTONE DEACETYLASE 8","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",5,"TYR A  83;HIS A 149;HIS A 162;PHE A 164;GLY A  17","None;MN3 A 300 (-3.2A);MN3 A 300 ( 3.3A);None;None","1.07A","4qa0A-3l57A:undetectable","4qa0A-3l57A:22.02"],["4QA0_B_SHHB404_2","HISTONE DEACETYLASE 8","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",5,"TYR A  83;HIS A 149;HIS A 162;PHE A 164;GLY A  17","None;MN3 A 300 (-3.2A);MN3 A 300 ( 3.3A);None;None","1.07A","4qa0B-3l57A:undetectable","4qa0B-3l57A:22.02"],["4QA2_A_SHHA404_1","HISTONE DEACETYLASE 8","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",5,"TYR A  83;HIS A 149;HIS A 162;PHE A 164;GLY A  17","None;MN3 A 300 (-3.2A);MN3 A 300 ( 3.3A);None;None","1.06A","4qa2A-3l57A:undetectable","4qa2A-3l57A:22.28"],["4QA2_B_SHHB404_1","HISTONE DEACETYLASE 8","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",5,"TYR A  83;HIS A 149;HIS A 162;PHE A 164;GLY A  17","None;MN3 A 300 (-3.2A);MN3 A 300 ( 3.3A);None;None","1.08A","4qa2B-3l57A:undetectable","4qa2B-3l57A:22.28"],["5N0O_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","3l57","MOBILIZATION PROTEIN TRAI","Escherichia coli",3,"ALA A 206;GLN A  96;THR A 104","EDO A 306 ( 3.8A);None;EDO A 305 (-4.3A)","0.69A","5n0oA-3l57A:undetectable","5n0oA-3l57A:22.52"]]