SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		4 / 7 PHE A 220
SER A 242
ALA A 228
ILE A 231
 None
 1.07A 1fxhA-3l5oA:
undetectable
1fxhB-3l5oA:
undetectable		 1fxhA-3l5oA:
21.17
1fxhB-3l5oA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 9 PRO A 201
THR A 203
PRO A 204
CYH A 175
GLY A  37
 EDO  A 307 ( 4.1A)
None
None
None
None
 1.48A 1h4oC-3l5oA:
undetectable
1h4oD-3l5oA:
undetectable		 1h4oC-3l5oA:
20.65
1h4oD-3l5oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 9 PRO A 201
THR A 203
PRO A 204
CYH A 175
GLY A  37
 EDO  A 307 ( 4.1A)
None
None
None
None
 1.48A 1h4oE-3l5oA:
undetectable
1h4oF-3l5oA:
undetectable		 1h4oE-3l5oA:
20.65
1h4oF-3l5oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		6 / 12 GLY A  39
VAL A 232
ASN A  83
LEU A  38
PRO A 201
ILE A 240
 None
None
None
None
EDO  A 307 ( 4.1A)
None
 1.38A 1zq9B-3l5oA:
4.9		 1zq9B-3l5oA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 10 PRO A 201
THR A 203
PRO A 204
CYH A 175
GLY A  37
 EDO  A 307 ( 4.1A)
None
None
None
None
 1.49A 2vl2A-3l5oA:
undetectable
2vl2C-3l5oA:
undetectable		 2vl2A-3l5oA:
23.38
2vl2C-3l5oA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A 217
THR A 203
LEU A 183
ILE A 173
SER A 177
 None
 1.24A 2ydoA-3l5oA:
undetectable		 2ydoA-3l5oA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		4 / 6 ARG A 230
PRO A 201
GLY A 244
MET A 221
 None
EDO  A 307 ( 4.1A)
None
None
 1.50A 3aqiA-3l5oA:
undetectable		 3aqiA-3l5oA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		4 / 7 VAL A 128
ASP A 180
LEU A 158
ILE A 196
 None
IMD  A 303 ( 2.8A)
IMD  A 303 (-4.2A)
None
 0.98A 3avpA-3l5oA:
undetectable		 3avpA-3l5oA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.05A 3bexC-3l5oA:
undetectable
3bexD-3l5oA:
undetectable		 3bexC-3l5oA:
23.02
3bexD-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 10 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.05A 3bexC-3l5oA:
undetectable
3bexD-3l5oA:
undetectable		 3bexC-3l5oA:
23.02
3bexD-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 10 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.04A 3bexE-3l5oA:
undetectable
3bexF-3l5oA:
undetectable		 3bexE-3l5oA:
23.02
3bexF-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.04A 3bexE-3l5oA:
undetectable
3bexF-3l5oA:
undetectable		 3bexE-3l5oA:
23.02
3bexF-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.09A 3bf1A-3l5oA:
undetectable
3bf1B-3l5oA:
undetectable		 3bf1A-3l5oA:
23.02
3bf1B-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.07A 3bf1A-3l5oA:
undetectable
3bf1B-3l5oA:
undetectable		 3bf1A-3l5oA:
23.02
3bf1B-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.08A 3bf1C-3l5oA:
undetectable
3bf1D-3l5oA:
undetectable		 3bf1C-3l5oA:
23.02
3bf1D-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.04A 3bf1C-3l5oA:
undetectable
3bf1D-3l5oA:
undetectable		 3bf1C-3l5oA:
23.02
3bf1D-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.05A 3bf1E-3l5oA:
undetectable
3bf1F-3l5oA:
undetectable		 3bf1E-3l5oA:
23.02
3bf1F-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.09A 3bf1E-3l5oA:
undetectable
3bf1F-3l5oA:
undetectable		 3bf1E-3l5oA:
23.02
3bf1F-3l5oA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 VAL A 232
GLY A  24
ILE A  77
LEU A  21
THR A  52
 None
 1.11A 4o5fA-3l5oA:
undetectable
4o5fB-3l5oA:
undetectable		 4o5fA-3l5oA:
22.36
4o5fB-3l5oA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A  21
THR A  52
VAL A 232
GLY A  24
ILE A  77
 None
 1.15A 4o5fA-3l5oA:
undetectable
4o5fB-3l5oA:
undetectable		 4o5fA-3l5oA:
22.36
4o5fB-3l5oA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 9 GLN A 215
GLU A 188
PRO A 184
LEU A 183
ILE A 173
 None
 1.40A 5i73A-3l5oA:
0.0		 5i73A-3l5oA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 10 GLY A  33
GLY A  35
ASN A 225
ILE A  30
PHE A 229
 None
 1.43A 5lbtA-3l5oA:
4.1
5lbtB-3l5oA:
4.0		 5lbtA-3l5oA:
22.26
5lbtB-3l5oA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 GLY A 129
HIS A 130
PHE A 113
ILE A 196
VAL A 171
 CL  A 301 ( 3.9A)
None
EDO  A 311 ( 4.8A)
None
None
 1.04A 5n0sA-3l5oA:
2.4		 5n0sA-3l5oA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		5 / 12 GLY A 129
HIS A 130
PHE A 113
ILE A 196
VAL A 171
 CL  A 301 ( 3.9A)
None
EDO  A 311 ( 4.8A)
None
None
 1.05A 5n4iA-3l5oA:
2.2		 5n4iA-3l5oA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY
(Desulfitobacteri
um
hafniense) 		4 / 5 LEU A 198
THR A 203
THR A 248
GLY A 219
 None
None
None
EDO  A 307 (-4.1A)
 1.11A 6gtqA-3l5oA:
undetectable		 6gtqA-3l5oA:
21.99