SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 1c9sL-3l6cA:
undetectable
1c9sM-3l6cA:
undetectable		 1c9sL-3l6cA:
14.11
1c9sM-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 1c9sM-3l6cA:
undetectable
1c9sN-3l6cA:
undetectable		 1c9sM-3l6cA:
14.11
1c9sN-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 1gtfO-3l6cA:
undetectable
1gtfP-3l6cA:
undetectable		 1gtfO-3l6cA:
14.11
1gtfP-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 1gtfP-3l6cA:
undetectable
1gtfQ-3l6cA:
undetectable		 1gtfP-3l6cA:
14.11
1gtfQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 1gtfT-3l6cA:
undetectable
1gtfU-3l6cA:
undetectable		 1gtfT-3l6cA:
14.11
1gtfU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 1gtfU-3l6cA:
undetectable
1gtfV-3l6cA:
undetectable		 1gtfU-3l6cA:
14.11
1gtfV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 1gtfL-3l6cA:
undetectable
1gtfV-3l6cA:
undetectable		 1gtfL-3l6cA:
14.11
1gtfV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 1gtnG-3l6cA:
undetectable
1gtnH-3l6cA:
undetectable		 1gtnG-3l6cA:
14.11
1gtnH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 1gtnL-3l6cA:
undetectable
1gtnM-3l6cA:
undetectable		 1gtnL-3l6cA:
14.11
1gtnM-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 1gtnN-3l6cA:
undetectable
1gtnO-3l6cA:
undetectable		 1gtnN-3l6cA:
14.11
1gtnO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  85
ALA A  90
THR A  81
HIS A  82
ALA A  60
 MLI  A 341 ( 4.9A)
None
None
None
None
 1.21A 1gtnO-3l6cA:
undetectable
1gtnP-3l6cA:
undetectable		 1gtnO-3l6cA:
14.11
1gtnP-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.14A 1gtnR-3l6cA:
undetectable
1gtnS-3l6cA:
undetectable		 1gtnR-3l6cA:
14.11
1gtnS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.16A 1gtnS-3l6cA:
undetectable
1gtnT-3l6cA:
undetectable		 1gtnS-3l6cA:
14.11
1gtnT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.16A 1gtnT-3l6cA:
undetectable
1gtnU-3l6cA:
undetectable		 1gtnT-3l6cA:
14.11
1gtnU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 1gtnU-3l6cA:
undetectable
1gtnV-3l6cA:
undetectable		 1gtnU-3l6cA:
14.11
1gtnV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 5 SER A 243
ASN A 229
ALA A 214
GLU A 210
 None
MN  A 340 ( 4.6A)
MN  A 340 (-4.0A)
MN  A 340 (-3.0A)
 1.38A 1lqtA-3l6cA:
undetectable
1lqtB-3l6cA:
undetectable		 1lqtA-3l6cA:
23.23
1lqtB-3l6cA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 5 SER A 243
ASN A 229
ALA A 214
GLU A 210
 None
MN  A 340 ( 4.6A)
MN  A 340 (-4.0A)
MN  A 340 (-3.0A)
 1.37A 1lquA-3l6cA:
undetectable
1lquB-3l6cA:
undetectable		 1lquA-3l6cA:
23.23
1lquB-3l6cA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 6 LEU A 246
VAL A 182
ILE A 252
ARG A  58
 None
 0.92A 1opjB-3l6cA:
undetectable		 1opjB-3l6cA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 ILE A  57
THR A  52
ALA A 117
GLY A  85
LEU A  91
 None
None
None
MLI  A 341 ( 4.9A)
None
 1.09A 1rjdA-3l6cA:
2.8		 1rjdA-3l6cA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 ILE A  57
THR A  52
ALA A 117
GLY A  85
LEU A  91
 None
None
None
MLI  A 341 ( 4.9A)
None
 1.07A 1rjdB-3l6cA:
undetectable		 1rjdB-3l6cA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 ILE A  57
THR A  52
ALA A 117
GLY A  85
LEU A  91
 None
None
None
MLI  A 341 ( 4.9A)
None
 1.06A 1rjdC-3l6cA:
2.8		 1rjdC-3l6cA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 1utdM-3l6cA:
undetectable
1utdN-3l6cA:
undetectable		 1utdM-3l6cA:
14.11
1utdN-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 1utdN-3l6cA:
undetectable
1utdO-3l6cA:
undetectable		 1utdN-3l6cA:
14.11
1utdO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 1utdR-3l6cA:
undetectable
1utdS-3l6cA:
undetectable		 1utdR-3l6cA:
14.11
1utdS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 1utdT-3l6cA:
undetectable
1utdU-3l6cA:
undetectable		 1utdT-3l6cA:
14.11
1utdU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 1utdU-3l6cA:
undetectable
1utdV-3l6cA:
undetectable		 1utdU-3l6cA:
14.11
1utdV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 1.02A 1v55C-3l6cA:
undetectable
1v55J-3l6cA:
undetectable		 1v55C-3l6cA:
21.73
1v55J-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 1.04A 1v55P-3l6cA:
undetectable
1v55W-3l6cA:
undetectable		 1v55P-3l6cA:
21.73
1v55W-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.84A 2dysC-3l6cA:
undetectable
2dysJ-3l6cA:
undetectable		 2dysC-3l6cA:
21.73
2dysJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.94A 2eikC-3l6cA:
undetectable
2eikJ-3l6cA:
undetectable		 2eikC-3l6cA:
21.73
2eikJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.94A 2eimC-3l6cA:
undetectable
2eimJ-3l6cA:
undetectable		 2eimC-3l6cA:
21.73
2eimJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 1.02A 2einC-3l6cA:
undetectable
2einJ-3l6cA:
undetectable		 2einC-3l6cA:
21.73
2einJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 6 LEU A 246
VAL A 182
ILE A 252
ARG A  58
 None
 1.02A 2hyyA-3l6cA:
undetectable		 2hyyA-3l6cA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 THR A  81
ILE A 125
GLY A  85
GLY A  88
ALA A 123
 None
None
MLI  A 341 ( 4.9A)
None
None
 0.91A 2yvlA-3l6cA:
2.7		 2yvlA-3l6cA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 THR A  81
ILE A 125
GLY A  85
GLY A  88
ALA A 123
 None
None
MLI  A 341 ( 4.9A)
None
None
 0.90A 2yvlB-3l6cA:
2.3		 2yvlB-3l6cA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 THR A  81
ILE A 125
GLY A  85
GLY A  88
ALA A 123
 None
None
MLI  A 341 ( 4.9A)
None
None
 0.87A 2yvlD-3l6cA:
2.1		 2yvlD-3l6cA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.82A 2zxwC-3l6cA:
undetectable
2zxwJ-3l6cA:
undetectable		 2zxwC-3l6cA:
21.73
2zxwJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 6 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.99A 2zxwP-3l6cA:
undetectable
2zxwW-3l6cA:
undetectable		 2zxwP-3l6cA:
21.73
2zxwW-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 6 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.91A 3ag1C-3l6cA:
undetectable
3ag1J-3l6cA:
undetectable		 3ag1C-3l6cA:
21.73
3ag1J-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 8 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.90A 3ag4C-3l6cA:
undetectable
3ag4J-3l6cA:
undetectable		 3ag4C-3l6cA:
21.73
3ag4J-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 ILE A 251
ILE A 160
VAL A 159
GLY A 162
VAL A 182
 None
 1.17A 3em0A-3l6cA:
undetectable		 3em0A-3l6cA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 5 ASN A 316
THR A  81
SER A  83
SER A 242
 None
None
MLI  A 341 (-2.5A)
MLI  A 341 (-2.7A)
 1.35A 3hlwB-3l6cA:
undetectable		 3hlwB-3l6cA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 LEU A  67
LEU A  91
ALA A  63
ASN A  62
LEU A  61
 None
 0.94A 3r9cA-3l6cA:
undetectable		 3r9cA-3l6cA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 GLN A 163
GLY A 162
ALA A  63
ARG A  65
ALA A  95
 None
 0.97A 3sudC-3l6cA:
undetectable		 3sudC-3l6cA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 ASP A  11
GLY A 162
SER A   8
PHE A   9
 None
 0.99A 4ac9C-3l6cA:
2.8		 4ac9C-3l6cA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 4 LEU A 290
ILE A 308
GLY A 289
PHE A 298
 None
 1.02A 4dc3A-3l6cA:
undetectable		 4dc3A-3l6cA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 ALA A 167
GLY A 162
ILE A 160
GLY A 192
ILE A 195
 None
 1.09A 4eatB-3l6cA:
undetectable		 4eatB-3l6cA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 8 ASP A 132
ASN A 229
ASP A 215
GLU A 210
 None
MN  A 340 ( 4.6A)
None
MN  A 340 (-3.0A)
 1.13A 4gkhC-3l6cA:
undetectable
4gkhK-3l6cA:
undetectable		 4gkhC-3l6cA:
20.64
4gkhK-3l6cA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 8 ASP A 132
ASN A 229
ASP A 215
GLU A 210
 None
MN  A 340 ( 4.6A)
None
MN  A 340 (-3.0A)
 1.14A 4gkiE-3l6cA:
undetectable
4gkiG-3l6cA:
undetectable		 4gkiE-3l6cA:
20.64
4gkiG-3l6cA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 8 GLY A 192
GLY A 187
ILE A 252
GLU A 210
 None
PLP  A 350 (-3.3A)
None
MN  A 340 (-3.0A)
 0.80A 4mwzB-3l6cA:
undetectable		 4mwzB-3l6cA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A 162
ALA A 161
ASP A  11
ILE A 193
THR A 248
 None
 1.19A 4njtD-3l6cA:
undetectable		 4njtD-3l6cA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 GLY A  88
GLN A  89
VAL A 106
TYR A 127
ASN A 112
 None
 1.07A 4pd5A-3l6cA:
undetectable		 4pd5A-3l6cA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 6 GLU A  47
THR A  26
LEU A  25
GLN A  50
 None
 1.22A 4qztA-3l6cA:
undetectable		 4qztA-3l6cA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 12 GLU A 283
GLU A  47
GLY A 289
ALA A 292
GLU A 266
 PLP  A 350 ( 3.8A)
None
None
None
None
 1.17A 4retC-3l6cA:
1.8		 4retC-3l6cA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
GLN A  89
ALA A 110
ASP A 238
SER A  84
 None
None
None
None
MLI  A 341 (-2.7A)
 1.21A 4wnuD-3l6cA:
undetectable		 4wnuD-3l6cA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.98A 5b1aC-3l6cA:
undetectable
5b1aJ-3l6cA:
undetectable		 5b1aC-3l6cA:
21.73
5b1aJ-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eeuC-3l6cA:
undetectable
5eeuD-3l6cA:
undetectable		 5eeuC-3l6cA:
14.11
5eeuD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeuG-3l6cA:
undetectable
5eeuH-3l6cA:
undetectable		 5eeuG-3l6cA:
14.11
5eeuH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eeuN-3l6cA:
undetectable
5eeuO-3l6cA:
undetectable		 5eeuN-3l6cA:
14.11
5eeuO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eeuP-3l6cA:
undetectable
5eeuQ-3l6cA:
undetectable		 5eeuP-3l6cA:
14.11
5eeuQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeuR-3l6cA:
undetectable
5eeuS-3l6cA:
undetectable		 5eeuR-3l6cA:
14.11
5eeuS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eeuS-3l6cA:
undetectable
5eeuT-3l6cA:
undetectable		 5eeuS-3l6cA:
14.11
5eeuT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eeuT-3l6cA:
undetectable
5eeuU-3l6cA:
undetectable		 5eeuT-3l6cA:
14.11
5eeuU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeuU-3l6cA:
undetectable
5eeuV-3l6cA:
undetectable		 5eeuU-3l6cA:
14.11
5eeuV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eevC-3l6cA:
undetectable
5eevD-3l6cA:
undetectable		 5eevC-3l6cA:
14.11
5eevD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eevG-3l6cA:
undetectable
5eevH-3l6cA:
undetectable		 5eevG-3l6cA:
14.11
5eevH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eevN-3l6cA:
undetectable
5eevO-3l6cA:
undetectable		 5eevN-3l6cA:
14.11
5eevO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eevO-3l6cA:
undetectable
5eevP-3l6cA:
undetectable		 5eevO-3l6cA:
14.11
5eevP-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eevP-3l6cA:
undetectable
5eevQ-3l6cA:
undetectable		 5eevP-3l6cA:
14.11
5eevQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eevR-3l6cA:
undetectable
5eevS-3l6cA:
undetectable		 5eevR-3l6cA:
14.11
5eevS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eevS-3l6cA:
undetectable
5eevT-3l6cA:
undetectable		 5eevS-3l6cA:
14.11
5eevT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eevT-3l6cA:
undetectable
5eevU-3l6cA:
undetectable		 5eevT-3l6cA:
14.11
5eevU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eevU-3l6cA:
undetectable
5eevV-3l6cA:
undetectable		 5eevU-3l6cA:
14.11
5eevV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eewC-3l6cA:
undetectable
5eewD-3l6cA:
undetectable		 5eewC-3l6cA:
14.11
5eewD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eewG-3l6cA:
undetectable
5eewH-3l6cA:
undetectable		 5eewG-3l6cA:
14.11
5eewH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eewN-3l6cA:
undetectable
5eewO-3l6cA:
undetectable		 5eewN-3l6cA:
14.11
5eewO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eewP-3l6cA:
undetectable
5eewQ-3l6cA:
undetectable		 5eewP-3l6cA:
14.11
5eewQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eewR-3l6cA:
undetectable
5eewS-3l6cA:
undetectable		 5eewR-3l6cA:
14.11
5eewS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eewS-3l6cA:
undetectable
5eewT-3l6cA:
undetectable		 5eewS-3l6cA:
14.11
5eewT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eewT-3l6cA:
undetectable
5eewU-3l6cA:
undetectable		 5eewT-3l6cA:
14.11
5eewU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eewU-3l6cA:
undetectable
5eewV-3l6cA:
undetectable		 5eewU-3l6cA:
14.11
5eewV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eexC-3l6cA:
undetectable
5eexD-3l6cA:
undetectable		 5eexC-3l6cA:
14.11
5eexD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eexG-3l6cA:
undetectable
5eexH-3l6cA:
undetectable		 5eexG-3l6cA:
14.11
5eexH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5eexI-3l6cA:
undetectable
5eexJ-3l6cA:
undetectable		 5eexI-3l6cA:
14.11
5eexJ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eexN-3l6cA:
undetectable
5eexO-3l6cA:
undetectable		 5eexN-3l6cA:
14.11
5eexO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eexP-3l6cA:
undetectable
5eexQ-3l6cA:
undetectable		 5eexP-3l6cA:
14.11
5eexQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eexR-3l6cA:
undetectable
5eexS-3l6cA:
undetectable		 5eexR-3l6cA:
14.11
5eexS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eexS-3l6cA:
undetectable
5eexT-3l6cA:
undetectable		 5eexS-3l6cA:
14.11
5eexT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eexT-3l6cA:
undetectable
5eexU-3l6cA:
undetectable		 5eexT-3l6cA:
14.11
5eexU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eexU-3l6cA:
undetectable
5eexV-3l6cA:
undetectable		 5eexU-3l6cA:
14.11
5eexV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eeyC-3l6cA:
undetectable
5eeyD-3l6cA:
undetectable		 5eeyC-3l6cA:
14.11
5eeyD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeyG-3l6cA:
undetectable
5eeyH-3l6cA:
undetectable		 5eeyG-3l6cA:
14.11
5eeyH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5eeyI-3l6cA:
undetectable
5eeyJ-3l6cA:
undetectable		 5eeyI-3l6cA:
14.11
5eeyJ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eeyN-3l6cA:
undetectable
5eeyO-3l6cA:
undetectable		 5eeyN-3l6cA:
14.11
5eeyO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eeyP-3l6cA:
undetectable
5eeyQ-3l6cA:
undetectable		 5eeyP-3l6cA:
14.11
5eeyQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeyR-3l6cA:
undetectable
5eeyS-3l6cA:
undetectable		 5eeyR-3l6cA:
14.11
5eeyS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eeyS-3l6cA:
undetectable
5eeyT-3l6cA:
undetectable		 5eeyS-3l6cA:
14.11
5eeyT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eeyT-3l6cA:
undetectable
5eeyU-3l6cA:
undetectable		 5eeyT-3l6cA:
14.11
5eeyU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eeyU-3l6cA:
undetectable
5eeyV-3l6cA:
undetectable		 5eeyU-3l6cA:
14.11
5eeyV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5eezC-3l6cA:
undetectable
5eezD-3l6cA:
undetectable		 5eezC-3l6cA:
14.11
5eezD-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eezG-3l6cA:
undetectable
5eezH-3l6cA:
undetectable		 5eezG-3l6cA:
14.11
5eezH-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5eezI-3l6cA:
undetectable
5eezJ-3l6cA:
undetectable		 5eezI-3l6cA:
14.11
5eezJ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5eezN-3l6cA:
undetectable
5eezO-3l6cA:
undetectable		 5eezN-3l6cA:
14.11
5eezO-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5eezP-3l6cA:
undetectable
5eezQ-3l6cA:
undetectable		 5eezP-3l6cA:
14.11
5eezQ-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eezR-3l6cA:
undetectable
5eezS-3l6cA:
undetectable		 5eezR-3l6cA:
14.11
5eezS-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5eezS-3l6cA:
undetectable
5eezT-3l6cA:
undetectable		 5eezS-3l6cA:
14.11
5eezT-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5eezT-3l6cA:
undetectable
5eezU-3l6cA:
undetectable		 5eezT-3l6cA:
14.11
5eezU-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5eezU-3l6cA:
undetectable
5eezV-3l6cA:
undetectable		 5eezU-3l6cA:
14.11
5eezV-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5ef0C-3l6cA:
undetectable
5ef0D-3l6cA:
undetectable		 5ef0C-3l6cA:
14.11
5ef0D-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef0G-3l6cA:
undetectable
5ef0H-3l6cA:
undetectable		 5ef0G-3l6cA:
14.11
5ef0H-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5ef0I-3l6cA:
undetectable
5ef0J-3l6cA:
undetectable		 5ef0I-3l6cA:
14.11
5ef0J-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5ef0N-3l6cA:
undetectable
5ef0O-3l6cA:
undetectable		 5ef0N-3l6cA:
14.11
5ef0O-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5ef0P-3l6cA:
undetectable
5ef0Q-3l6cA:
undetectable		 5ef0P-3l6cA:
14.11
5ef0Q-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef0R-3l6cA:
undetectable
5ef0S-3l6cA:
undetectable		 5ef0R-3l6cA:
14.11
5ef0S-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5ef0S-3l6cA:
undetectable
5ef0T-3l6cA:
undetectable		 5ef0S-3l6cA:
14.11
5ef0T-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5ef0T-3l6cA:
undetectable
5ef0U-3l6cA:
undetectable		 5ef0T-3l6cA:
14.11
5ef0U-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef0U-3l6cA:
undetectable
5ef0V-3l6cA:
undetectable		 5ef0U-3l6cA:
14.11
5ef0V-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5ef1C-3l6cA:
undetectable
5ef1D-3l6cA:
undetectable		 5ef1C-3l6cA:
14.11
5ef1D-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5ef1G-3l6cA:
undetectable
5ef1H-3l6cA:
undetectable		 5ef1G-3l6cA:
14.11
5ef1H-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5ef1I-3l6cA:
undetectable
5ef1J-3l6cA:
undetectable		 5ef1I-3l6cA:
14.11
5ef1J-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5ef1N-3l6cA:
undetectable
5ef1O-3l6cA:
undetectable		 5ef1N-3l6cA:
14.11
5ef1O-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5ef1P-3l6cA:
undetectable
5ef1Q-3l6cA:
undetectable		 5ef1P-3l6cA:
14.11
5ef1Q-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef1R-3l6cA:
undetectable
5ef1S-3l6cA:
undetectable		 5ef1R-3l6cA:
14.11
5ef1S-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5ef1S-3l6cA:
undetectable
5ef1T-3l6cA:
undetectable		 5ef1S-3l6cA:
14.11
5ef1T-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5ef1T-3l6cA:
undetectable
5ef1U-3l6cA:
undetectable		 5ef1T-3l6cA:
14.11
5ef1U-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef1U-3l6cA:
undetectable
5ef1V-3l6cA:
undetectable		 5ef1U-3l6cA:
14.11
5ef1V-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5ef2C-3l6cA:
undetectable
5ef2D-3l6cA:
undetectable		 5ef2C-3l6cA:
14.11
5ef2D-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef2G-3l6cA:
undetectable
5ef2H-3l6cA:
undetectable		 5ef2G-3l6cA:
14.11
5ef2H-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5ef2I-3l6cA:
undetectable
5ef2J-3l6cA:
undetectable		 5ef2I-3l6cA:
14.11
5ef2J-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5ef2N-3l6cA:
undetectable
5ef2O-3l6cA:
undetectable		 5ef2N-3l6cA:
14.11
5ef2O-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5ef2P-3l6cA:
undetectable
5ef2Q-3l6cA:
undetectable		 5ef2P-3l6cA:
14.11
5ef2Q-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef2R-3l6cA:
undetectable
5ef2S-3l6cA:
undetectable		 5ef2R-3l6cA:
14.11
5ef2S-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5ef2S-3l6cA:
undetectable
5ef2T-3l6cA:
undetectable		 5ef2S-3l6cA:
14.11
5ef2T-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5ef2T-3l6cA:
undetectable
5ef2U-3l6cA:
undetectable		 5ef2T-3l6cA:
14.11
5ef2U-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef2U-3l6cA:
undetectable
5ef2V-3l6cA:
undetectable		 5ef2U-3l6cA:
14.11
5ef2V-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 9 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.18A 5ef3C-3l6cA:
undetectable
5ef3D-3l6cA:
undetectable		 5ef3C-3l6cA:
14.11
5ef3D-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef3G-3l6cA:
undetectable
5ef3H-3l6cA:
undetectable		 5ef3G-3l6cA:
14.11
5ef3H-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 11 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.19A 5ef3I-3l6cA:
undetectable
5ef3J-3l6cA:
undetectable		 5ef3I-3l6cA:
14.11
5ef3J-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.23A 5ef3N-3l6cA:
undetectable
5ef3O-3l6cA:
undetectable		 5ef3N-3l6cA:
14.11
5ef3O-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.20A 5ef3P-3l6cA:
undetectable
5ef3Q-3l6cA:
undetectable		 5ef3P-3l6cA:
14.11
5ef3Q-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef3R-3l6cA:
undetectable
5ef3S-3l6cA:
undetectable		 5ef3R-3l6cA:
14.11
5ef3S-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.17A 5ef3S-3l6cA:
undetectable
5ef3T-3l6cA:
undetectable		 5ef3S-3l6cA:
14.11
5ef3T-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.22A 5ef3T-3l6cA:
undetectable
5ef3U-3l6cA:
undetectable		 5ef3T-3l6cA:
14.11
5ef3U-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 GLY A  88
HIS A  87
ALA A 102
THR A  81
ILE A 104
 None
 1.21A 5ef3U-3l6cA:
undetectable
5ef3V-3l6cA:
undetectable		 5ef3U-3l6cA:
14.11
5ef3V-3l6cA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.97A 5iy5C-3l6cA:
undetectable
5iy5J-3l6cA:
undetectable		 5iy5C-3l6cA:
21.45
5iy5J-3l6cA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		5 / 10 LEU A 312
ILE A 282
GLY A 315
GLY A  53
ALA A 286
 None
 0.99A 5o96C-3l6cA:
undetectable
5o96D-3l6cA:
undetectable		 5o96C-3l6cA:
23.41
5o96D-3l6cA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		3 / 3 GLY A 186
ASN A 154
ARG A 135
 PLP  A 350 (-3.6A)
PLP  A 350 (-4.3A)
MLI  A 341 (-3.2A)
 0.77A 5w7bD-3l6cA:
undetectable		 5w7bD-3l6cA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3l6c SERINE RACEMASE
(Rattus
norvegicus) 		4 / 7 LEU A 171
GLN A 173
LEU A 200
PHE A   9
 None
 0.89A 5z84C-3l6cA:
undetectable
5z84J-3l6cA:
undetectable		 5z84C-3l6cA:
21.73
5z84J-3l6cA:
12.28