SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 ILE A 127
ILE A  70
VAL A  27
LEU A  28
GLN A  31
 None
 0.97A 1qhyA-3l6dA:
undetectable		 1qhyA-3l6dA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 5 LEU A  92
GLY A 120
HIS A 121
ILE A  97
 None
 0.95A 1xf1A-3l6dA:
undetectable		 1xf1A-3l6dA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 6 LEU A  92
GLY A 120
HIS A 121
ILE A  97
 None
 0.90A 1xf1B-3l6dA:
undetectable		 1xf1B-3l6dA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 11 TYR A 100
GLY A 162
THR A 164
GLU A 158
ILE A  70
 None
 1.45A 2dr2A-3l6dA:
undetectable		 2dr2A-3l6dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 7 VAL A  72
GLY A  18
ALA A  19
MET A  20
 None
 0.86A 2wekB-3l6dA:
5.6		 2wekB-3l6dA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 GLN A  31
MET A  24
ALA A  25
VAL A  14
HIS A 143
 None
 1.29A 3b0wA-3l6dA:
undetectable		 3b0wA-3l6dA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 GLN A  31
MET A  24
ALA A  25
VAL A  14
HIS A 143
 None
 1.31A 3b0wB-3l6dA:
undetectable		 3b0wB-3l6dA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 8 ASN A 103
THR A 101
LEU A  73
HIS A  80
 None
 1.16A 3kp2A-3l6dA:
undetectable
3kp2B-3l6dA:
undetectable		 3kp2A-3l6dA:
19.93
3kp2B-3l6dA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 9 LEU A 157
SER A 141
THR A 101
ASP A  99
PHE A 150
 None
 1.29A 4drhB-3l6dA:
0.0		 4drhB-3l6dA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 8 HIS A  80
ASN A  76
LEU A  83
ASP A  99
ILE A  97
 None
 1.49A 4l7iA-3l6dA:
undetectable		 4l7iA-3l6dA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 ALA A  45
GLY A  18
GLY A  16
LEU A  74
LEU A  73
 None
 1.09A 4lg1B-3l6dA:
4.7		 4lg1B-3l6dA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		3 / 3 TRP A 262
GLN A 259
THR A 263
 None
 0.85A 4m2xA-3l6dA:
undetectable		 4m2xA-3l6dA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 8 LEU A 160
VAL A  98
VAL A  72
LEU A 156
 None
 1.11A 4q0bA-3l6dA:
undetectable		 4q0bA-3l6dA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 LEU A 156
PHE A   8
VAL A  12
THR A  96
GLY A 119
 None
 1.30A 4q15A-3l6dA:
3.3		 4q15A-3l6dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 12 LEU A 156
PHE A   8
VAL A  12
THR A  96
GLY A 119
 None
 1.35A 4q15B-3l6dA:
3.4		 4q15B-3l6dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 5 HIS A 140
ILE A 127
ILE A 142
TYR A 100
 None
 1.04A 5dnuA-3l6dA:
undetectable		 5dnuA-3l6dA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 4 VAL A  88
ALA A  62
ILE A  97
THR A  69
 None
 1.08A 5e4dB-3l6dA:
undetectable		 5e4dB-3l6dA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		5 / 9 LEU A 157
SER A 141
THR A 101
ASP A  99
PHE A 150
 None
 1.47A 5gpgB-3l6dA:
0.0		 5gpgB-3l6dA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 7 THR A 101
ASP A  99
TYR A 122
GLY A 108
 None
 1.12A 5hwaA-3l6dA:
undetectable		 5hwaA-3l6dA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 8 LEU A 111
GLU A  81
LEU A  73
ILE A  15
 None
 0.86A 5mzjA-3l6dA:
undetectable		 5mzjA-3l6dA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 8 HIS A 143
VAL A  98
LEU A 160
ALA A 161
 None
 0.86A 5tt3H-3l6dA:
undetectable		 5tt3H-3l6dA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 6 LEU A  73
VAL A  82
LEU A  83
VAL A  59
 None
 0.97A 5x7zA-3l6dA:
undetectable		 5x7zA-3l6dA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		3 / 3 ALA A 226
PHE A 235
GLN A 233
 None
 0.73A 6eceA-3l6dA:
2.5		 6eceA-3l6dA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3l6d PUTATIVE
OXIDOREDUCTASE
(Pseudomonas
putida) 		4 / 6 MET A  85
ALA A  62
LEU A  63
ALA A  91
 None
 1.02A 6fosB-3l6dA:
undetectable		 6fosB-3l6dA:
13.07