SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 12 THR A  87
GLY A  10
VAL A 104
TYR A 148
ASN A 144
 None
SO4  A 500 (-3.3A)
None
None
None
 1.09A 1n2xA-3l6eA:
9.5		 1n2xA-3l6eA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		4 / 6 ARG A  17
ALA A  18
ILE A 181
PRO A 200
 None
 1.28A 1oniB-3l6eA:
undetectable
1oniC-3l6eA:
undetectable		 1oniB-3l6eA:
22.61
1oniC-3l6eA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		4 / 7 PHE A 158
LEU A 130
VAL A 120
THR A 119
 None
 0.89A 2qblA-3l6eA:
undetectable		 2qblA-3l6eA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		4 / 8 PHE A 158
VAL A 120
THR A 119
ILE A 113
 None
 0.92A 2qbmA-3l6eA:
undetectable		 2qbmA-3l6eA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		4 / 7 LEU A  58
SER A 111
THR A 112
VAL A 115
 None
 1.18A 2uz2A-3l6eA:
undetectable		 2uz2A-3l6eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		3 / 3 HIS A  61
GLU A  62
HIS A  60
 None
 0.79A 3ba0A-3l6eA:
undetectable		 3ba0A-3l6eA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		3 / 3 SER A 107
GLY A  86
GLY A  88
 None
 0.55A 3bogA-3l6eA:
undetectable
3bogC-3l6eA:
undetectable		 3bogA-3l6eA:
undetectable
3bogC-3l6eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 9 GLY A  34
ALA A  56
ASP A  57
ASP A  63
VAL A  66
 SO4  A 500 (-3.3A)
None
None
None
None
 1.04A 3ektA-3l6eA:
undetectable		 3ektA-3l6eA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		3 / 3 ARG A  39
VAL A  51
THR A  20
 None
 0.86A 3pwrA-3l6eA:
undetectable		 3pwrA-3l6eA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 9 GLY A  34
ALA A  56
ASP A  57
ASP A  63
VAL A  66
 SO4  A 500 (-3.3A)
None
None
None
None
 1.04A 4dqcB-3l6eA:
undetectable		 4dqcB-3l6eA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 11 ALA A  50
GLY A  48
GLU A  44
GLY A  75
HIS A  28
 None
 1.18A 4e47A-3l6eA:
undetectable		 4e47A-3l6eA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 11 ALA A  50
GLY A  48
GLU A  44
GLY A  75
HIS A  28
 None
 1.16A 4e47B-3l6eA:
undetectable		 4e47B-3l6eA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		4 / 8 GLY A  76
GLY A   4
LEU A  80
GLU A  79
 None
 0.75A 4mwzB-3l6eA:
undetectable		 4mwzB-3l6eA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Aeromonas
hydrophila) 		5 / 9 GLY A  34
ALA A  56
ASP A  57
ASP A  63
VAL A  66
 SO4  A 500 (-3.3A)
None
None
None
None
 1.06A 4njtD-3l6eA:
undetectable		 4njtD-3l6eA:
16.23