SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		5 / 11 GLY A 151
SER A 152
ALA A 156
ALA A 158
PHE A 176
 None
 1.07A 1ukbA-3l6iA:
undetectable		 1ukbA-3l6iA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		3 / 3 GLU A  60
GLU A  21
LEU A 105
 None
 0.57A 1v8bA-3l6iA:
undetectable		 1v8bA-3l6iA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 6 LEU A 127
MET A  86
THR A  85
LEU A  73
 None
 1.08A 2dysA-3l6iA:
undetectable
2dysJ-3l6iA:
undetectable		 2dysA-3l6iA:
14.64
2dysJ-3l6iA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		5 / 12 LEU A  73
ALA A 134
LEU A  90
MET A  86
LEU A 128
 None
NA  A   1 (-4.1A)
None
None
None
 1.28A 2oaxE-3l6iA:
undetectable		 2oaxE-3l6iA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 6 LEU A 127
MET A  86
THR A  85
LEU A  73
 None
 1.08A 2zxwA-3l6iA:
undetectable
2zxwJ-3l6iA:
undetectable		 2zxwA-3l6iA:
14.64
2zxwJ-3l6iA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 6 LEU A 127
MET A  86
THR A  85
LEU A  73
 None
 1.07A 3abmA-3l6iA:
undetectable
3abmJ-3l6iA:
undetectable		 3abmA-3l6iA:
14.64
3abmJ-3l6iA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 5 LEU A  88
GLY A  69
MET A 108
PHE A  34
 None
 1.21A 3uq6B-3l6iA:
undetectable		 3uq6B-3l6iA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 4 LEU A  88
GLY A  69
MET A 108
PHE A  34
 None
 1.25A 3vaqB-3l6iA:
undetectable		 3vaqB-3l6iA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		4 / 6 MET A 124
LEU A 127
PRO A  41
TYR A 130
 None
 0.96A 3vkxA-3l6iA:
undetectable		 3vkxA-3l6iA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3l6i UNCHARACTERIZED
LIPOPROTEIN YCEB
(Escherichia
coli) 		5 / 12 VAL A 167
LEU A  28
LEU A 105
LEU A  67
THR A  54
 None
 1.19A 5hnwB-3l6iA:
undetectable		 5hnwB-3l6iA:
15.51