SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		5 / 12 ALA A 697
GLY A 807
ILE A 806
THR A 802
ILE A 723
 None
 1.07A 1c6zA-3l6vA:
undetectable		 1c6zA-3l6vA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 6 THR A 653
THR A 649
ILE A 673
LEU A 675
 None
 0.91A 3deuB-3l6vA:
undetectable		 3deuB-3l6vA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		5 / 12 ALA A 776
GLY A 824
SER A 825
LEU A 822
ALA A 793
 None
 1.27A 3ou6C-3l6vA:
undetectable		 3ou6C-3l6vA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		5 / 12 ALA A 776
GLY A 824
SER A 825
LEU A 822
ALA A 793
 None
 1.27A 3ou7C-3l6vA:
undetectable		 3ou7C-3l6vA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 8 SER A 733
GLU A 783
TYR A 786
GLY A 855
 None
 1.00A 4fgzA-3l6vA:
undetectable
4fgzB-3l6vA:
undetectable		 4fgzA-3l6vA:
20.60
4fgzB-3l6vA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		3 / 3 PRO A 535
ASN A 584
HIS A 586
 None
 1.01A 4ma3H-3l6vA:
undetectable
4ma3L-3l6vA:
undetectable		 4ma3H-3l6vA:
24.07
4ma3L-3l6vA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		5 / 10 LEU A 659
ALA A 640
GLU A 638
ARG A 637
GLY A 689
 None
 1.36A 5dxbA-3l6vA:
undetectable		 5dxbA-3l6vA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 5 GLY A 785
THR A 782
GLN A 854
THR A 857
 None
 1.24A 5h5fA-3l6vA:
undetectable		 5h5fA-3l6vA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		5 / 12 GLY A 615
GLY A 610
ARG A 561
GLY A 546
SER A 543
 None
 1.11A 5hikA-3l6vA:
undetectable		 5hikA-3l6vA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 8 ARG A 813
GLY A 815
GLN A 854
THR A 810
 None
 0.79A 5sxqA-3l6vA:
undetectable		 5sxqA-3l6vA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 8 ARG A 813
GLY A 815
GLN A 854
THR A 810
 None
 0.81A 5sxtA-3l6vA:
undetectable		 5sxtA-3l6vA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 8 ARG A 813
GLY A 815
GLN A 854
THR A 810
 None
 0.79A 5sxtB-3l6vA:
undetectable		 5sxtB-3l6vA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3l6v DNA GYRASE SUBUNIT A
(Xanthomonas
campestris) 		4 / 8 ARG A 813
GLY A 815
GLN A 854
THR A 810
 None
 0.90A 5syjB-3l6vA:
undetectable		 5syjB-3l6vA:
21.92