SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 ILE A 541
ILE A 579
TYR A 543
TYR A 667
ILE A 666
 None
 1.26A 1jtxA-3l7iA:
undetectable		 1jtxA-3l7iA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 ASN A 517
ARG A 518
ASP A 608
 None
 0.97A 2qe6A-3l7iA:
undetectable		 2qe6A-3l7iA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 ASN A 517
ARG A 518
ASP A 608
 None
 0.96A 2qe6B-3l7iA:
undetectable		 2qe6B-3l7iA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 SER A 359
THR A 427
PHE A 497
 None
 0.71A 2x91A-3l7iA:
undetectable		 2x91A-3l7iA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 ARG A 652
GLY A 653
SER A 495
 None
 0.64A 2xctB-3l7iA:
undetectable		 2xctB-3l7iA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 THR A 438
GLN A 437
ASP A 480
TYR A 415
 None
 1.33A 2xz5A-3l7iA:
undetectable
2xz5C-3l7iA:
undetectable		 2xz5A-3l7iA:
15.62
2xz5C-3l7iA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 7 HIS A 420
ILE A 355
TYR A 383
HIS A 715
 None
None
CL  A 744 ( 4.8A)
None
 0.92A 4g5jA-3l7iA:
undetectable		 4g5jA-3l7iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 PRO A 665
ILE A 564
PHE A 638
TYR A 543
LEU A 677
 None
 1.50A 4kosA-3l7iA:
undetectable		 4kosA-3l7iA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 MET A 460
ASP A 549
PHE A 552
 None
 0.94A 4xeyA-3l7iA:
undetectable		 4xeyA-3l7iA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		3 / 3 MET A 460
ASP A 549
PHE A 552
 None
 0.98A 4xeyB-3l7iA:
undetectable		 4xeyB-3l7iA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 ASP A 661
ASP A 629
PHE A 628
GLY A 631
TYR A 695
 None
 1.13A 5hfjA-3l7iA:
2.6		 5hfjA-3l7iA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 ASP A 661
ASP A 629
PHE A 628
GLY A 631
TYR A 695
 None
 1.19A 5hfjE-3l7iA:
undetectable		 5hfjE-3l7iA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 ASP A 661
ASP A 629
PHE A 628
GLY A 631
TYR A 695
 None
 1.15A 5hfjH-3l7iA:
undetectable		 5hfjH-3l7iA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		5 / 12 LEU A 429
TYR A 439
LEU A 482
PHE A 472
LEU A 451
 None
 1.19A 5iepA-3l7iA:
undetectable		 5iepA-3l7iA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 ASP A 629
ILE A 632
ARG A 511
ASN A 517
 None
 1.20A 6hisA-3l7iA:
undetectable
6hisB-3l7iA:
undetectable		 6hisA-3l7iA:
9.01
6hisB-3l7iA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 ASP A 629
ILE A 632
ARG A 511
ASN A 517
 None
 1.20A 6hisB-3l7iA:
undetectable
6hisC-3l7iA:
undetectable		 6hisB-3l7iA:
9.01
6hisC-3l7iA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 ASP A 629
ILE A 632
ARG A 511
ASN A 517
 None
 1.19A 6hisC-3l7iA:
undetectable
6hisD-3l7iA:
undetectable		 6hisC-3l7iA:
9.01
6hisD-3l7iA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 ASP A 629
ILE A 632
ARG A 511
ASN A 517
 None
 1.21A 6hisD-3l7iA:
undetectable
6hisE-3l7iA:
undetectable		 6hisD-3l7iA:
9.01
6hisE-3l7iA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3l7i TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F
(Staphylococcus
epidermidis) 		4 / 8 ASN A 517
ASP A 629
ILE A 632
ARG A 511
 None
 1.20A 6hisA-3l7iA:
undetectable
6hisE-3l7iA:
undetectable		 6hisA-3l7iA:
9.01
6hisE-3l7iA:
9.01