SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		4 / 5 ASP A  40
SER A  39
VAL A  19
GLY A  23
 None
 1.06A 3rxhA-3l7vA:
undetectable		 3rxhA-3l7vA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		5 / 12 CYH A  95
ILE A 129
LEU A  69
PHE A  82
HIS A  86
 None
 1.35A 3vn2A-3l7vA:
undetectable		 3vn2A-3l7vA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		3 / 3 LYS A   0
THR A   2
ILE A  18
 None
 0.82A 4e0fB-3l7vA:
undetectable		 4e0fB-3l7vA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		4 / 8 ALA A 134
ASN A 162
ILE A 169
GLY A  33
 None
 0.80A 4r20A-3l7vA:
undetectable		 4r20A-3l7vA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		5 / 9 ALA A 134
ASN A 162
ILE A 169
VAL A 166
GLY A  33
 None
 1.31A 4r20B-3l7vA:
undetectable		 4r20B-3l7vA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		3 / 3 LYS A  31
ARG A 234
VAL A 204
 None
SO4  A 262 ( 3.5A)
None
 1.06A 4x3uA-3l7vA:
undetectable
4x3uB-3l7vA:
undetectable		 4x3uA-3l7vA:
14.71
4x3uB-3l7vA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		4 / 5 GLU A 146
GLU A  17
GLU A 141
PHE A  16
 None
 1.28A 5onlA-3l7vA:
undetectable		 5onlA-3l7vA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		4 / 7 GLY A  59
TRP A  99
TYR A 104
ASP A 120
 None
 1.25A 5vlmG-3l7vA:
undetectable		 5vlmG-3l7vA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C
(Streptococcus
mutans) 		4 / 5 GLU A 146
GLU A  17
GLU A 141
PHE A  16
 None
 1.30A 6hrjA-3l7vA:
undetectable		 6hrjA-3l7vA:
20.13