SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.12A 1dfoA-3l7wA:
undetectable		 1dfoA-3l7wA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.13A 1dfoB-3l7wA:
undetectable		 1dfoB-3l7wA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.12A 1dfoC-3l7wA:
undetectable		 1dfoC-3l7wA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.12A 1dfoD-3l7wA:
undetectable		 1dfoD-3l7wA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.14A 1eqbA-3l7wA:
undetectable		 1eqbA-3l7wA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.15A 1eqbB-3l7wA:
undetectable		 1eqbB-3l7wA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.15A 1eqbC-3l7wA:
undetectable		 1eqbC-3l7wA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		5 / 12 LEU A  56
GLY A  54
LEU A  47
ALA A  53
SER A  19
 None
 1.15A 1eqbD-3l7wA:
undetectable		 1eqbD-3l7wA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		4 / 5 LEU A  56
ILE A  28
ILE A  17
ALA A  16
 None
 0.56A 2i2zA-3l7wA:
undetectable		 2i2zA-3l7wA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		4 / 4 LEU A  50
ILE A  28
ILE A  17
ALA A  16
 None
 0.78A 2i30A-3l7wA:
undetectable		 2i30A-3l7wA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3l7w PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1704
(Streptococcus
mutans) 		4 / 4 LEU A  56
ILE A  28
ILE A  17
ALA A  16
 None
 0.68A 2i30A-3l7wA:
undetectable		 2i30A-3l7wA:
10.61