SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		4 / 6 ARG B 338
LEU B 328
GLU B 363
ILE B 331
 None
 0.88A 2fcnA-3l82B:
undetectable
2fcnB-3l82B:
undetectable		 2fcnA-3l82B:
15.21
2fcnB-3l82B:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO B 177
PHE B 223
LYS B 230
 None
 1.20A 3bjwG-3l82B:
undetectable		 3bjwG-3l82B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		5 / 10 ALA B 180
VAL B 285
ILE B 214
GLY B 220
VAL B 221
 None
 1.09A 3oxvB-3l82B:
undetectable		 3oxvB-3l82B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		5 / 10 ALA B 180
VAL B 285
ILE B 214
GLY B 220
VAL B 221
 None
 1.02A 3oxwB-3l82B:
undetectable		 3oxwB-3l82B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		4 / 5 GLY B 288
ASP B 287
ARG B 178
MET B 198
 None
 1.32A 3qx3A-3l82B:
undetectable		 3qx3A-3l82B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY B 183
PRO B 184
GLY B 185
LEU B 236
ILE B 233
 None
 1.01A 4n49A-3l82B:
undetectable		 4n49A-3l82B:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO B 340
MET B 339
TYR B 343
 None
 0.99A 4qa0B-3l82B:
undetectable		 4qa0B-3l82B:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO B 340
MET B 339
TYR B 343
 None
 0.98A 4qa0A-3l82B:
undetectable		 4qa0A-3l82B:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO B 340
MET B 339
TYR B 343
 None
 1.00A 4qa2B-3l82B:
undetectable		 4qa2B-3l82B:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		5 / 12 VAL B 292
LEU B 350
LEU B 358
THR B 362
ALA B 345
 None
 0.93A 4x1kA-3l82B:
undetectable
4x1kB-3l82B:
3.3		 4x1kA-3l82B:
19.52
4x1kB-3l82B:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		4 / 5 GLY B 288
ASP B 287
ARG B 178
MET B 198
 None
 1.33A 5zrfB-3l82B:
2.2		 5zrfB-3l82B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 3l82 F-BOX ONLY PROTEIN 4
(Homo
sapiens) 		4 / 4 GLY B 288
ASP B 287
ARG B 178
MET B 198
 None
 1.28A 5zrfA-3l82B:
undetectable		 5zrfA-3l82B:
14.76