SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3l88 FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 6 LEU A 174
GLY A 176
ASN A 182
ILE A 146
 None
 0.86A 1xf1B-3l88A:
undetectable		 1xf1B-3l88A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3l88 FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 11 THR A 191
ALA A 190
PHE A 185
VAL A 172
ILE A 272
 None
 1.41A 4claA-3l88A:
undetectable		 4claA-3l88A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3l88 FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 8 VAL A 268
TYR A 259
SER A 262
ALA A 297
 None
 0.75A 4m48A-3l88A:
undetectable		 4m48A-3l88A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3l88 FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 MET A 184
ASP A 154
ARG A 195
 None
 0.86A 5z6jA-3l88A:
undetectable		 5z6jA-3l88A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3l88 FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 MET A 184
ASP A 154
ARG A 195
 None
 0.97A 5z6kA-3l88A:
undetectable		 5z6kA-3l88A:
19.21