SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		4 / 8 ASP A 141
ILE A 142
THR A 143
LEU A 155
 None
 0.90A 1hmyA-3l93A:
3.5		 1hmyA-3l93A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		5 / 12 TYR A   7
LEU A  34
ALA A  55
LEU A  54
ARG A  51
 None
 1.28A 1mx8A-3l93A:
undetectable		 1mx8A-3l93A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		3 / 3 ASN A  84
ALA A  83
LYS A   4
 None
 0.99A 3runA-3l93A:
undetectable		 3runA-3l93A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		5 / 12 LEU A  48
THR A 151
VAL A  52
ALA A  53
LEU A  54
 None
 0.95A 5kpcA-3l93A:
3.0		 5kpcA-3l93A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		4 / 7 VAL A  87
ILE A  85
VAL A  32
ALA A   5
 None
 0.47A 5ospA-3l93A:
undetectable		 5ospA-3l93A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		4 / 7 VAL A  87
ILE A  85
VAL A  32
ALA A   5
 None
 0.47A 5osrA-3l93A:
undetectable		 5osrA-3l93A:
19.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		5 / 5 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
 0.55A 6jmjA-3l93A:
26.6		 6jmjA-3l93A:
56.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		6 / 7 GLY A   9
THR A  10
PHE A  11
HIS A  18
SER A 128
SER A 129
 None
 0.56A 6jnhA-3l93A:
26.6		 6jnhA-3l93A:
56.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Yersinia
pestis) 		5 / 6 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
 0.60A 6jogA-3l93A:
26.5		 6jogA-3l93A:
56.17