SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		5 / 11 ASP A  96
GLN A 101
VAL A 119
ILE A 138
VAL A  14
 None
 1.28A 2vcdA-3l9dA:
undetectable		 2vcdA-3l9dA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		4 / 8 SER A  35
ARG A  25
ILE A  37
ASP A  83
 None
 1.13A 4d33A-3l9dA:
undetectable		 4d33A-3l9dA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		4 / 7 SER A  35
ARG A  25
ILE A  37
ASP A  83
 None
 1.14A 4d33B-3l9dA:
undetectable		 4d33B-3l9dA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		3 / 3 TYR A 114
ARG A 141
SER A 116
 None
 0.98A 4khpI-3l9dA:
undetectable
4khpJ-3l9dA:
undetectable		 4khpI-3l9dA:
16.99
4khpJ-3l9dA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		5 / 6 SER A  49
GLU A  52
GLY A  42
ARG A  75
GLY A  73
 None
 1.07A 5cdnA-3l9dA:
1.8
5cdnB-3l9dA:
undetectable		 5cdnA-3l9dA:
20.43
5cdnB-3l9dA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		5 / 12 PHE A  21
ILE A  76
MET A  97
VAL A 119
ILE A 140
 None
 1.42A 5mlmA-3l9dA:
undetectable		 5mlmA-3l9dA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3l9d PUTATIVE GTP
PYROPHOSPHOKINASE
(Streptococcus
mutans) 		5 / 12 LEU A   7
VAL A  44
ALA A 136
ALA A  72
GLY A  73
 None
 1.18A 5tzoB-3l9dA:
undetectable		 5tzoB-3l9dA:
20.85