SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3l9j TNFALPHA
(Homo
sapiens) 		4 / 6 GLY C  90
TYR C  97
ALA C  95
GLU C  98
 None
 0.94A 1dmaB-3l9jC:
undetectable		 1dmaB-3l9jC:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 3l9j TNFALPHA
(Homo
sapiens) 		5 / 12 GLU C  92
LYS C  59
LEU C 155
LEU C 112
GLY C 113
 None
 1.48A 6f3nA-3l9jC:
undetectable		 6f3nA-3l9jC:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 3l9j TNFALPHA
(Homo
sapiens) 		5 / 12 GLU C  92
LYS C  59
LEU C 155
LEU C 112
GLY C 113
 None
 1.42A 6f3nC-3l9jC:
undetectable		 6f3nC-3l9jC:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 3l9j TNFALPHA
(Homo
sapiens) 		5 / 12 GLU C  92
LYS C  59
LEU C 155
LEU C 112
GLY C 113
 None
 1.48A 6f3nD-3l9jC:
undetectable		 6f3nD-3l9jC:
13.89