SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3l9k RE64145P
(Drosophila
melanogaster) 		4 / 7 MET A  47
ALA A  44
ILE A  90
ILE A  79
 None
 0.93A 1upfB-3l9kA:
undetectable		 1upfB-3l9kA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 3l9k RE64145P
(Drosophila
melanogaster) 		3 / 3 ARG A  73
GLN A  93
PRO A  95
 None
 0.83A 2qhfA-3l9kA:
undetectable		 2qhfA-3l9kA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3l9k RE64145P
(Drosophila
melanogaster) 		5 / 11 ALA A  51
ALA A  54
VAL A  81
ALA A  44
GLY A  45
 None
 0.94A 3mg0K-3l9kA:
undetectable
3mg0L-3l9kA:
undetectable		 3mg0K-3l9kA:
18.47
3mg0L-3l9kA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3l9k RE64145P
(Drosophila
melanogaster) 		4 / 7 LEU A  35
SER A  33
ILE A  22
VAL A  24
 None
 1.14A 4tvtA-3l9kA:
undetectable		 4tvtA-3l9kA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3l9k RE64145P
(Drosophila
melanogaster) 		4 / 5 ASN A  94
VAL A  81
LEU A  70
SER A  74
 None
 1.29A 6a7pA-3l9kA:
undetectable		 6a7pA-3l9kA:
11.13