SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_A_CCSA47_0 (GLUTATHIONE S-TRANSFERASE)	3l9r	CD1B3 (Bos taurus)	5 / 7	LEU A 161 THR A 165 LEU A 170 GLY A 101 LEU A 12	None None None None L9R A 284 ( 4.1A)	1.16A	1gtiA-3l9rA: undetectable	1gtiA-3l9rA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_B_CCSB47_0 (GLUTATHIONE S-TRANSFERASE)	3l9r	CD1B3 (Bos taurus)	5 / 7	LEU A 161 THR A 165 LEU A 170 GLY A 101 LEU A 12	None None None None L9R A 284 ( 4.1A)	1.30A	1gtiB-3l9rA: undetectable	1gtiB-3l9rA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_E_CCSE47_0 (GLUTATHIONE S-TRANSFERASE)	3l9r	CD1B3 (Bos taurus)	4 / 7	THR A 165 LEU A 170 GLY A 101 LEU A 12	None None None L9R A 284 ( 4.1A)	1.04A	1gtiE-3l9rA: undetectable	1gtiE-3l9rA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3l9r	CD1B3 (Bos taurus)	5 / 12	LEU A 104 GLY A 30 LEU A 181 LEU A 174 VAL A 173	None L9R A 284 ( 4.8A) None None None	0.97A	3adxB-3l9rA: undetectable	3adxB-3l9rA: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KKZ_A_SAMA301_0 (UNCHARACTERIZED PROTEIN Q5LES9)	3l9r	CD1B3 (Bos taurus)	5 / 12	ARG A 168 GLY A 56 GLY A 172 LEU A 174 GLU A 62	NAG A 501 ( 4.5A) None NAG A 501 ( 4.1A) None NAG A 501 ( 4.5A)	0.96A	3kkzA-3l9rA: undetectable	3kkzA-3l9rA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KKZ_B_SAMB302_0 (UNCHARACTERIZED PROTEIN Q5LES9)	3l9r	CD1B3 (Bos taurus)	5 / 12	ARG A 168 GLY A 56 GLY A 172 LEU A 174 GLU A 62	NAG A 501 ( 4.5A) None NAG A 501 ( 4.1A) None NAG A 501 ( 4.5A)	0.92A	3kkzB-3l9rA: undetectable	3kkzB-3l9rA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUV_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	3l9r	CD1B3 (Bos taurus)	5 / 12	LEU A 118 PHE A 144 PHE A 94 VAL A 81 PHE A 77	L9R A 284 ( 4.4A) L9R A 284 (-4.4A) None L9R A 284 ( 4.0A) L9R A 284 (-4.8A)	1.49A	3nuvA-3l9rA: undetectable	3nuvA-3l9rA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_K_CLMK221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3l9r	CD1B3 (Bos taurus)	5 / 10	SER A 16 PHE A 18 LEU A 114 VAL A 124 PHE A 144	None None None None L9R A 284 (-4.4A)	1.45A	3u9fK-3l9rA: undetectable	3u9fK-3l9rA: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_B_SAMB1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3l9r	CD1B3 (Bos taurus)	5 / 12	TYR A 212 GLY A 6 LEU A 50 GLY A 30 ASP A 34	None None None L9R A 284 ( 4.8A) None	1.14A	4blvB-3l9rA: undetectable	4blvB-3l9rA: 22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKT_A_TLFA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3l9r	CD1B3 (Bos taurus)	3 / 3	LEU A 32 TYR A 169 SER A 54	None	0.88A	5iktA-3l9rA: undetectable	5iktA-3l9rA: 17.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_A_CCSA47_0","GLUTATHIONE S-TRANSFERASE","3l9r","CD1B3","Bos taurus",5,"LEU A 161;THR A 165;LEU A 170;GLY A 101;LEU A  12","None;None;None;None;L9R A 284 ( 4.1A)","1.16A","1gtiA-3l9rA:undetectable","1gtiA-3l9rA:19.05"],["1GTI_B_CCSB47_0","GLUTATHIONE S-TRANSFERASE","3l9r","CD1B3","Bos taurus",5,"LEU A 161;THR A 165;LEU A 170;GLY A 101;LEU A  12","None;None;None;None;L9R A 284 ( 4.1A)","1.30A","1gtiB-3l9rA:undetectable","1gtiB-3l9rA:19.05"],["1GTI_E_CCSE47_0","GLUTATHIONE S-TRANSFERASE","3l9r","CD1B3","Bos taurus",4,"THR A 165;LEU A 170;GLY A 101;LEU A  12","None;None;None;L9R A 284 ( 4.1A)","1.04A","1gtiE-3l9rA:undetectable","1gtiE-3l9rA:19.05"],["3ADX_B_IMNB3_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3l9r","CD1B3","Bos taurus",5,"LEU A 104;GLY A  30;LEU A 181;LEU A 174;VAL A 173","None;L9R A 284 ( 4.8A);None;None;None","0.97A","3adxB-3l9rA:undetectable","3adxB-3l9rA:23.47"],["3KKZ_A_SAMA301_0","UNCHARACTERIZED PROTEIN Q5LES9","3l9r","CD1B3","Bos taurus",5,"ARG A 168;GLY A  56;GLY A 172;LEU A 174;GLU A  62","NAG A 501 ( 4.5A);None;NAG A 501 ( 4.1A);None;NAG A 501 ( 4.5A)","0.96A","3kkzA-3l9rA:undetectable","3kkzA-3l9rA:24.78"],["3KKZ_B_SAMB302_0","UNCHARACTERIZED PROTEIN Q5LES9","3l9r","CD1B3","Bos taurus",5,"ARG A 168;GLY A  56;GLY A 172;LEU A 174;GLU A  62","NAG A 501 ( 4.5A);None;NAG A 501 ( 4.1A);None;NAG A 501 ( 4.5A)","0.92A","3kkzB-3l9rA:undetectable","3kkzB-3l9rA:24.78"],["3NUV_A_ASDA126_1","STEROID DELTA-ISOMERASE","3l9r","CD1B3","Bos taurus",5,"LEU A 118;PHE A 144;PHE A  94;VAL A  81;PHE A  77","L9R A 284 ( 4.4A);L9R A 284 (-4.4A);None;L9R A 284 ( 4.0A);L9R A 284 (-4.8A)","1.49A","3nuvA-3l9rA:undetectable","3nuvA-3l9rA:20.27"],["3U9F_K_CLMK221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3l9r","CD1B3","Bos taurus",5,"SER A  16;PHE A  18;LEU A 114;VAL A 124;PHE A 144","None;None;None;None;L9R A 284 (-4.4A)","1.45A","3u9fK-3l9rA:undetectable","3u9fK-3l9rA:22.65"],["4BLV_B_SAMB1281_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3l9r","CD1B3","Bos taurus",5,"TYR A 212;GLY A   6;LEU A  50;GLY A  30;ASP A  34","None;None;None;L9R A 284 ( 4.8A);None","1.14A","4blvB-3l9rA:undetectable","4blvB-3l9rA:22.94"],["5IKT_A_TLFA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3l9r","CD1B3","Bos taurus",3,"LEU A  32;TYR A 169;SER A  54","None","0.88A","5iktA-3l9rA:undetectable","5iktA-3l9rA:17.97"]]