SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3la2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		3 / 3 GLU A 106
ILE A 105
ARG A  88
 None
None
AKG  A 224 (-3.8A)
 0.85A 1cd2A-3la2A:
undetectable		 1cd2A-3la2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.89A 1cqeA-3la2A:
undetectable		 1cqeA-3la2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.89A 1cqeB-3la2A:
undetectable		 1cqeB-3la2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.88A 1eqhA-3la2A:
undetectable		 1eqhA-3la2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.87A 1eqhB-3la2A:
undetectable		 1eqhB-3la2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A  51
LEU A 172
LEU A  68
ILE A 179
ALA A 178
 None
 1.02A 1ha2A-3la2A:
undetectable		 1ha2A-3la2A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 11 PHE A 160
LEU A 174
LEU A 156
ILE A 183
ALA A 182
 None
 1.03A 1ha2A-3la2A:
undetectable		 1ha2A-3la2A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.99A 2aylA-3la2A:
undetectable		 2aylA-3la2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.99A 2aylB-3la2A:
undetectable		 2aylB-3la2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.05A 3ln1A-3la2A:
undetectable		 3ln1A-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.04A 3ln1B-3la2A:
undetectable		 3ln1B-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.05A 3ln1C-3la2A:
undetectable		 3ln1C-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.94A 3n8wA-3la2A:
undetectable		 3n8wA-3la2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.94A 3n8zA-3la2A:
undetectable		 3n8zA-3la2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.00A 3nt1A-3la2A:
undetectable		 3nt1A-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.96A 3pghC-3la2A:
undetectable		 3pghC-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.97A 3pghD-3la2A:
undetectable		 3pghD-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		4 / 6 ASP A 159
LEU A 156
ALA A  67
LEU A  69
 None
 1.12A 3rozA-3la2A:
undetectable		 3rozA-3la2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.02A 3rr3A-3la2A:
undetectable		 3rr3A-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.02A 3rr3B-3la2A:
undetectable		 3rr3B-3la2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 149
LEU A 156
CYH A 157
ILE A 210
ILE A 179
 None
 0.82A 4a79A-3la2A:
undetectable		 4a79A-3la2A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 149
LEU A 156
CYH A 157
ILE A 210
ILE A 179
 None
 0.79A 4a79B-3la2A:
undetectable		 4a79B-3la2A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 11 LEU A 149
LEU A 156
CYH A 157
ILE A 210
ILE A 179
 None
 0.87A 4a7aA-3la2A:
undetectable		 4a7aA-3la2A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 149
LEU A 156
CYH A 157
ILE A 210
ILE A 179
 None
 0.83A 4a7aB-3la2A:
undetectable		 4a7aB-3la2A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 10 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.92A 4ph9A-3la2A:
undetectable		 4ph9A-3la2A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 10 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.91A 4ph9B-3la2A:
undetectable		 4ph9B-3la2A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		4 / 7 VAL A  52
LEU A  54
SER A  55
GLU A  63
 None
AKG  A 224 (-4.3A)
None
None
 1.02A 4zphA-3la2A:
undetectable
4zphB-3la2A:
undetectable		 4zphA-3la2A:
22.25
4zphB-3la2A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		4 / 6 VAL A  44
ALA A 103
GLN A 107
VAL A 108
 None
 1.01A 5i8fA-3la2A:
undetectable		 5i8fA-3la2A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.98A 5ikrB-3la2A:
undetectable		 5ikrB-3la2A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.95A 5jvzA-3la2A:
undetectable		 5jvzA-3la2A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 0.94A 5jvzB-3la2A:
0.4		 5jvzB-3la2A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 108
LEU A 112
GLY A  76
SER A  79
LEU A  80
 None
None
AKG  A 224 (-3.1A)
None
None
 1.05A 5jw1A-3la2A:
undetectable		 5jw1A-3la2A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3la2 GLOBAL NITROGEN
REGULATOR
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A 129
LEU A  69
PHE A  95
 AKG  A 224 (-2.5A)
None
None
 0.77A 6nknP-3la2A:
undetectable		 6nknP-3la2A:
22.30