SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3lat BIFUNCTIONAL
AUTOLYSIN
(Staphylococcus
epidermidis) 		4 / 6 ASP A  90
HIS A 187
HIS A 124
ASP A  65
 None
None
ZN  A 221 ( 3.0A)
ZN  A 220 (-2.3A)
 0.86A 3c0zC-3latA:
undetectable		 3c0zC-3latA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lat BIFUNCTIONAL
AUTOLYSIN
(Staphylococcus
epidermidis) 		3 / 3 ILE A 120
PHE A 129
HIS A 181
 None
 0.69A 3h0aA-3latA:
undetectable		 3h0aA-3latA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 3lat BIFUNCTIONAL
AUTOLYSIN
(Staphylococcus
epidermidis) 		4 / 8 PHE A  84
GLY A 173
SER A 169
ILE A 168
 None
 0.92A 3ihzB-3latA:
undetectable		 3ihzB-3latA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3lat BIFUNCTIONAL
AUTOLYSIN
(Staphylococcus
epidermidis) 		4 / 4 ALA A 140
PRO A  54
LEU A 103
HIS A  86
 None
 1.40A 5eskA-3latA:
undetectable		 5eskA-3latA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3lat BIFUNCTIONAL
AUTOLYSIN
(Staphylococcus
epidermidis) 		4 / 7 LEU A 184
TYR A 183
THR A  62
LEU A 194
 None
 0.80A 5jq7B-3latA:
undetectable		 5jq7B-3latA:
24.51