SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ASP A 327
ASP A 328
TYR A 356
ARG A 424
 None
 1.45A 1cebA-3laxA:
undetectable		 1cebA-3laxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 6 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 1.01A 3wg7N-3laxA:
undetectable
3wg7W-3laxA:
undetectable		 3wg7N-3laxA:
11.47
3wg7W-3laxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 TYR A 356
VAL A 371
ILE A 401
LEU A 347
 None
 1.12A 4xo7B-3laxA:
undetectable		 4xo7B-3laxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 0.89A 5b1aA-3laxA:
undetectable
5b1aJ-3laxA:
undetectable		 5b1aA-3laxA:
11.47
5b1aJ-3laxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 0.89A 5b1bN-3laxA:
undetectable
5b1bW-3laxA:
undetectable		 5b1bN-3laxA:
11.47
5b1bW-3laxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 0.88A 5b3sA-3laxA:
undetectable
5b3sJ-3laxA:
undetectable		 5b3sA-3laxA:
11.47
5b3sJ-3laxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 0.86A 5zcpA-3laxA:
undetectable
5zcpJ-3laxA:
undetectable		 5zcpA-3laxA:
11.47
5zcpJ-3laxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lax PHENYLACETATE-COENZY
ME A LIGASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 358
ARG A 406
THR A 394
LEU A 397
 None
 0.92A 5zcqA-3laxA:
undetectable
5zcqJ-3laxA:
undetectable		 5zcqA-3laxA:
11.47
5zcqJ-3laxA:
19.15