SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 3lb6 INTERLEUKIN-13
RECEPTOR SUBUNIT
ALPHA-2
(Homo
sapiens) 		3 / 3 ASP D 318
VAL D 312
PRO D 266
 None
 0.65A 2avvA-3lb6D:
undetectable		 2avvA-3lb6D:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 3lb6 INTERLEUKIN-13
RECEPTOR SUBUNIT
ALPHA-2
(Homo
sapiens) 		5 / 12 PHE D 246
LEU D 256
TYR D 293
LEU D 295
LEU D 283
 None
 1.23A 2bxfA-3lb6D:
undetectable		 2bxfA-3lb6D:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3lb6 INTERLEUKIN-13
RECEPTOR SUBUNIT
ALPHA-2
(Homo
sapiens) 		3 / 3 GLU D  70
SER D 121
VAL D  32
 None
 0.76A 3eeoA-3lb6D:
undetectable		 3eeoA-3lb6D:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 11 LEU A  83
SER A  82
ILE A  37
PHE A  70
GLU A  49
 None
 1.42A 3ko0A-3lb6A:
undetectable
3ko0B-3lb6A:
undetectable
3ko0C-3lb6A:
undetectable
3ko0D-3lb6A:
undetectable		 3ko0A-3lb6A:
21.58
3ko0B-3lb6A:
21.58
3ko0C-3lb6A:
21.58
3ko0D-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 11 GLU A  49
LEU A  83
SER A  82
ILE A  37
PHE A  70
 None
 1.43A 3ko0C-3lb6A:
undetectable
3ko0D-3lb6A:
undetectable
3ko0E-3lb6A:
undetectable
3ko0F-3lb6A:
undetectable		 3ko0C-3lb6A:
21.58
3ko0D-3lb6A:
21.58
3ko0E-3lb6A:
21.58
3ko0F-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 11 LEU A  83
SER A  82
ILE A  37
PHE A  70
GLU A  49
 None
 1.40A 3ko0C-3lb6A:
undetectable
3ko0D-3lb6A:
undetectable
3ko0E-3lb6A:
undetectable
3ko0F-3lb6A:
undetectable		 3ko0C-3lb6A:
21.58
3ko0D-3lb6A:
21.58
3ko0E-3lb6A:
21.58
3ko0F-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 11 GLU A  49
LEU A  83
SER A  82
ILE A  37
PHE A  70
 None
 1.36A 3ko0E-3lb6A:
undetectable
3ko0F-3lb6A:
undetectable
3ko0G-3lb6A:
undetectable
3ko0H-3lb6A:
undetectable		 3ko0E-3lb6A:
21.58
3ko0F-3lb6A:
21.58
3ko0G-3lb6A:
21.58
3ko0H-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 12 GLU A  49
LEU A  83
SER A  82
ILE A  37
PHE A  70
 None
 1.42A 3ko0G-3lb6A:
undetectable
3ko0H-3lb6A:
undetectable
3ko0I-3lb6A:
undetectable
3ko0J-3lb6A:
undetectable		 3ko0G-3lb6A:
21.58
3ko0H-3lb6A:
21.58
3ko0I-3lb6A:
21.58
3ko0J-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 11 GLU A  49
LEU A  83
SER A  82
ILE A  37
PHE A  70
 None
 1.36A 3ko0K-3lb6A:
undetectable
3ko0L-3lb6A:
undetectable
3ko0M-3lb6A:
undetectable
3ko0N-3lb6A:
undetectable		 3ko0K-3lb6A:
21.58
3ko0L-3lb6A:
21.58
3ko0M-3lb6A:
21.58
3ko0N-3lb6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 3lb6 INTERLEUKIN-13
(Homo
sapiens) 		5 / 10 LEU A  83
SER A  82
ILE A  37
PHE A  70
GLU A  49
 None
 1.42A 3ko0O-3lb6A:
undetectable
3ko0P-3lb6A:
undetectable
3ko0Q-3lb6A:
undetectable
3ko0R-3lb6A:
undetectable		 3ko0O-3lb6A:
21.58
3ko0P-3lb6A:
21.58
3ko0Q-3lb6A:
21.58
3ko0R-3lb6A:
21.58