SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 GLY A  78
GLY A  99
TRP A  95
VAL A 103
 None
 0.92A 1dbbH-3lb9A:
undetectable
1dbbL-3lb9A:
1.3		 1dbbH-3lb9A:
25.65
1dbbL-3lb9A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 ASP A 166
SER A 165
TYR A 170
HIS A  28
 None
 1.36A 2bteA-3lb9A:
undetectable		 2bteA-3lb9A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 6 TYR A 145
GLY A  52
TYR A 134
ASN A 128
 None
 1.25A 2g72A-3lb9A:
undetectable		 2g72A-3lb9A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 ASP A 148
SER A 165
VAL A 163
LEU A  39
 None
 1.06A 2hdnE-3lb9A:
undetectable
2hdnF-3lb9A:
undetectable
2hdnH-3lb9A:
undetectable		 2hdnE-3lb9A:
13.14
2hdnF-3lb9A:
17.46
2hdnH-3lb9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 SER A 165
VAL A 163
LEU A  39
ASP A 148
 None
 1.06A 2hdnF-3lb9A:
undetectable
2hdnG-3lb9A:
undetectable
2hdnH-3lb9A:
undetectable		 2hdnF-3lb9A:
17.46
2hdnG-3lb9A:
13.14
2hdnH-3lb9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 12 SER A   9
LEU A  39
ILE A 172
ALA A  31
ARG A 114
 None
 1.28A 2v0mC-3lb9A:
undetectable		 2v0mC-3lb9A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 12 GLY A 135
VAL A 146
ALA A  44
LEU A  39
ILE A 142
 None
 1.05A 3ku1H-3lb9A:
undetectable		 3ku1H-3lb9A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 TYR A 130
TYR A 145
LEU A 133
PHE A  25
 None
 1.15A 4yv5A-3lb9A:
undetectable		 4yv5A-3lb9A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 TYR A 130
TYR A 145
LEU A 133
PHE A  25
 None
 1.21A 4yv5B-3lb9A:
undetectable		 4yv5B-3lb9A:
19.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 THR A 156
THR A 175
ARG A 177
GLN A   6
 None
 0.87A 5tzoA-3lb9A:
12.4		 5tzoA-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 173
THR A 175
ARG A 177
GLN A   6
TRP A   8
 None
 0.59A 5tzoA-3lb9A:
12.4		 5tzoA-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		7 / 12 VAL A 102
TRP A 136
TYR A 145
PRO A 181
TRP A   8
TYR A  45
GLY A  52
 None
 0.82A 5tzoA-3lb9A:
12.4		 5tzoA-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		6 / 12 VAL A 102
TRP A 136
TYR A 145
TRP A   8
TYR A  45
GLY A  52
 None
 0.58A 5tzoB-3lb9A:
12.4		 5tzoB-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		3 / 3 ARG A 177
PRO A 181
TYR A  53
 None
 0.63A 5tzoB-3lb9A:
12.4		 5tzoB-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 THR A 156
THR A 175
ARG A 177
GLN A   6
 None
 0.90A 5tzoB-3lb9A:
12.4		 5tzoB-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 173
THR A 175
ARG A 177
GLN A   6
TRP A   8
 None
 0.50A 5tzoB-3lb9A:
12.4		 5tzoB-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		7 / 12 VAL A 102
TRP A 136
TYR A 145
PRO A 181
TRP A   8
TYR A  45
GLY A  52
 None
 0.85A 5tzoC-3lb9A:
12.5		 5tzoC-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 THR A 156
THR A 175
ARG A 177
GLN A   6
 None
 0.86A 5tzoC-3lb9A:
12.5		 5tzoC-3lb9A:
60.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 173
THR A 175
ARG A 177
GLN A   6
TRP A   8
 None
 0.54A 5tzoC-3lb9A:
12.5		 5tzoC-3lb9A:
60.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 5 GLY A 151
THR A 152
SER A  56
SER A  55
 None
 0.85A 6jmjA-3lb9A:
undetectable		 6jmjA-3lb9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 GLY A 151
THR A 152
SER A  56
SER A  55
 None
 0.82A 6jnhA-3lb9A:
undetectable		 6jnhA-3lb9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3lb9 ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 6 GLY A 151
THR A 152
SER A  56
SER A  55
 None
 0.83A 6jogA-3lb9A:
undetectable		 6jogA-3lb9A:
21.94