SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lbf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
12 / 12 GLN A  56
GLY A  83
GLY A  85
GLU A 104
ILE A 106
LEU A 109
ASP A 131
GLY A 132
THR A 148
ALA A 149
VAL A 200
LEU A 202
SAH  A 300 (-3.8A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.3A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.3A)
SAH  A 300 ( 3.7A)
None
SAH  A 300 (-4.2A)
0.43A 1jg2A-3lbfA:
32.8
1jg2A-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
11 / 11 GLN A  56
GLY A  83
GLY A  85
GLU A 104
ARG A 105
ILE A 106
LEU A 109
ASP A 131
GLY A 132
THR A 148
LEU A 202
SAH  A 300 (-3.8A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
None
SAH  A 300 (-4.3A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.3A)
SAH  A 300 (-4.2A)
0.32A 1jg3A-3lbfA:
33.1
1jg3A-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
6 / 11 GLN A  56
GLY A  85
GLU A 104
ARG A 105
LEU A 109
GLY A 130
SAH  A 300 (-3.8A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
None
SAH  A 300 (-4.8A)
None
1.40A 1jg3A-3lbfA:
33.1
1jg3A-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
11 / 11 GLN A  56
GLY A  83
GLY A  85
GLU A 104
ARG A 105
ILE A 106
LEU A 109
ASP A 131
GLY A 132
THR A 148
LEU A 202
SAH  A 300 (-3.8A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
None
SAH  A 300 (-4.3A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.3A)
SAH  A 300 (-4.2A)
0.30A 1jg3B-3lbfA:
33.0
1jg3B-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
6 / 11 GLN A  56
GLY A  85
GLU A 104
ARG A 105
LEU A 109
GLY A 130
SAH  A 300 (-3.8A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
None
SAH  A 300 (-4.8A)
None
1.37A 1jg3B-3lbfA:
33.0
1jg3B-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
9 / 12 GLN A  56
THR A  57
SER A  59
GLY A  85
GLY A 132
THR A 148
ALA A 149
VAL A 200
LEU A 202
SAH  A 300 (-3.8A)
None
None
SAH  A 300 (-3.4A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.3A)
SAH  A 300 ( 3.7A)
None
SAH  A 300 (-4.2A)
0.58A 1jg4A-3lbfA:
33.2
1jg4A-3lbfA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
8 / 8 GLU A  81
GLY A  83
SER A  86
GLU A 104
ARG A 105
ILE A 106
LEU A 109
ASP A 131
SAH  A 300 ( 4.7A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.5A)
SAH  A 300 (-2.9A)
None
SAH  A 300 (-4.3A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
0.35A 1jg4A-3lbfA:
33.2
1jg4A-3lbfA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 12 GLU A  81
GLY A  83
GLY A  85
LEU A 109
ASP A 131
SAH  A 300 ( 4.7A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
0.58A 1qaoA-3lbfA:
8.9
1qaoA-3lbfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 4 VAL A 197
LEU A  71
ILE A 167
LEU A 168
None
0.94A 2byoA-3lbfA:
undetectable
2byoA-3lbfA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 11 GLU A  81
GLY A  83
GLY A  85
GLU A 104
ASP A 131
SAH  A 300 ( 4.7A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
SAH  A 300 (-3.7A)
0.54A 3dxyA-3lbfA:
8.0
3dxyA-3lbfA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 12 ILE A 167
ILE A 146
GLU A  81
ILE A  82
ARG A 184
None
None
SAH  A 300 ( 4.7A)
SAH  A 300 ( 4.8A)
None
1.25A 3fpjB-3lbfA:
11.0
3fpjB-3lbfA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 11 GLY A  83
GLY A  85
GLU A 104
LEU A 109
ASP A 131
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
0.76A 3grvA-3lbfA:
11.8
3grvA-3lbfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
6 / 12 GLU A  81
GLY A  83
GLY A  85
GLU A 104
LEU A 109
ASP A 131
SAH  A 300 ( 4.7A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.8A)
SAH  A 300 (-3.7A)
0.84A 3gryA-3lbfA:
11.7
3gryA-3lbfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 11 LEU A  93
VAL A  23
VAL A  64
LEU A  73
GLU A  81
None
None
None
None
SAH  A 300 ( 4.7A)
1.44A 3m8pA-3lbfA:
0.3
3m8pB-3lbfA:
undetectable
3m8pA-3lbfA:
17.02
3m8pB-3lbfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 5 THR A  68
ILE A 146
GLU A  81
PHE A 199
None
None
SAH  A 300 ( 4.7A)
None
1.40A 4ac9C-3lbfA:
undetectable
4ac9C-3lbfA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 5 THR A  68
ILE A 146
GLU A  81
PHE A 199
None
None
SAH  A 300 ( 4.7A)
None
1.43A 4acaC-3lbfA:
undetectable
4acaC-3lbfA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 5 THR A  68
ILE A 146
GLU A  81
PHE A 199
None
None
SAH  A 300 ( 4.7A)
None
1.40A 4acbC-3lbfA:
undetectable
4acbC-3lbfA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 7 GLY A  83
GLY A  85
SER A  86
GLU A 104
ASP A 131
SAH  A 300 (-3.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-2.5A)
SAH  A 300 (-2.9A)
SAH  A 300 (-3.7A)
0.72A 5ergB-3lbfA:
12.8
5ergB-3lbfA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 12 ASP A 131
THR A  57
GLY A  85
SER A  86
GLU A 104
SAH  A 300 (-3.7A)
None
SAH  A 300 (-3.4A)
SAH  A 300 (-2.5A)
SAH  A 300 (-2.9A)
1.09A 5hfjF-3lbfA:
3.1
5hfjF-3lbfA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 8 ILE A 146
LEU A  73
ALA A  26
LEU A  27
None
0.83A 5y7pE-3lbfA:
undetectable
5y7pE-3lbfA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
5 / 12 ILE A  58
GLU A  81
GLY A  83
TYR A  88
ALA A 149
SAH  A 300 ( 4.6A)
SAH  A 300 ( 4.7A)
SAH  A 300 (-3.4A)
None
SAH  A 300 ( 3.7A)
0.98A 5zw4A-3lbfA:
12.5
5zw4A-3lbfA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 5 VAL A 125
THR A 127
VAL A  64
LEU A  71
None
0.83A 6bqgA-3lbfA:
undetectable
6bqgA-3lbfA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
3lbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Escherichia
coli)
4 / 6 VAL A  23
LEU A  10
LEU A  13
ARG A  14
None
0.98A 6e43A-3lbfA:
undetectable
6e43A-3lbfA:
19.51