SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 1d1vA-3lccA:
undetectable
1d1vB-3lccA:
undetectable		 1d1vA-3lccA:
18.00
1d1vB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 1d1vA-3lccA:
undetectable
1d1vB-3lccA:
undetectable		 1d1vA-3lccA:
18.00
1d1vB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 1d1wA-3lccA:
1.6
1d1wB-3lccA:
undetectable		 1d1wA-3lccA:
18.00
1d1wB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 1d1wA-3lccA:
1.6
1d1wB-3lccA:
undetectable		 1d1wA-3lccA:
18.00
1d1wB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 1d1xA-3lccA:
undetectable
1d1xB-3lccA:
undetectable		 1d1xA-3lccA:
18.00
1d1xB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 1d1xA-3lccA:
0.0
1d1xB-3lccA:
0.0		 1d1xA-3lccA:
18.00
1d1xB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 1dm8A-3lccA:
undetectable
1dm8B-3lccA:
undetectable		 1dm8A-3lccA:
18.00
1dm8B-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 1dm8A-3lccA:
undetectable
1dm8B-3lccA:
undetectable		 1dm8A-3lccA:
18.00
1dm8B-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 1dmiA-3lccA:
undetectable
1dmiB-3lccA:
undetectable		 1dmiA-3lccA:
18.00
1dmiB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.26A 1fopA-3lccA:
undetectable
1fopB-3lccA:
undetectable		 1fopA-3lccA:
18.00
1fopB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 1fopA-3lccA:
undetectable
1fopB-3lccA:
undetectable		 1fopA-3lccA:
18.00
1fopB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 1nseA-3lccA:
undetectable
1nseB-3lccA:
undetectable		 1nseA-3lccA:
18.00
1nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 1nseA-3lccA:
undetectable
1nseB-3lccA:
undetectable		 1nseA-3lccA:
18.00
1nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 1p6lA-3lccA:
undetectable
1p6lB-3lccA:
undetectable		 1p6lA-3lccA:
17.81
1p6lB-3lccA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 1p6lA-3lccA:
undetectable
1p6lB-3lccA:
undetectable		 1p6lA-3lccA:
17.81
1p6lB-3lccA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 1p6mA-3lccA:
undetectable
1p6mB-3lccA:
undetectable		 1p6mA-3lccA:
17.81
1p6mB-3lccA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 1p6mA-3lccA:
undetectable
1p6mB-3lccA:
undetectable		 1p6mA-3lccA:
17.81
1p6mB-3lccA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.25A 1p6nA-3lccA:
undetectable
1p6nB-3lccA:
undetectable		 1p6nA-3lccA:
17.81
1p6nB-3lccA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 1q2oA-3lccA:
undetectable
1q2oB-3lccA:
undetectable		 1q2oA-3lccA:
17.86
1q2oB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 1q2oA-3lccA:
undetectable
1q2oB-3lccA:
undetectable		 1q2oA-3lccA:
17.86
1q2oB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 1rs8A-3lccA:
undetectable
1rs8B-3lccA:
undetectable		 1rs8A-3lccA:
17.86
1rs8B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 1rs8A-3lccA:
undetectable
1rs8B-3lccA:
undetectable		 1rs8A-3lccA:
17.86
1rs8B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 1rs9A-3lccA:
undetectable
1rs9B-3lccA:
undetectable		 1rs9A-3lccA:
17.86
1rs9B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 1rs9A-3lccA:
undetectable
1rs9B-3lccA:
undetectable		 1rs9A-3lccA:
17.86
1rs9B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.25A 1zzrA-3lccA:
undetectable
1zzrB-3lccA:
undetectable		 1zzrA-3lccA:
20.37
1zzrB-3lccA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 1zzsA-3lccA:
undetectable
1zzsB-3lccA:
undetectable		 1zzsA-3lccA:
17.86
1zzsB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 1zzsA-3lccA:
undetectable
1zzsB-3lccA:
undetectable		 1zzsA-3lccA:
17.86
1zzsB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 1zzuA-3lccA:
undetectable
1zzuB-3lccA:
undetectable		 1zzuA-3lccA:
20.37
1zzuB-3lccA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.25A 1zzuA-3lccA:
undetectable
1zzuB-3lccA:
undetectable		 1zzuA-3lccA:
20.37
1zzuB-3lccA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 MET A 149
VAL A 124
ASP A 123
SER A 156
ILE A 145
 None
SAH  A 300 (-4.1A)
SAH  A 300 (-3.8A)
None
None
 1.16A 2dcfA-3lccA:
undetectable		 2dcfA-3lccA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 2hx2A-3lccA:
undetectable
2hx2B-3lccA:
undetectable		 2hx2A-3lccA:
17.86
2hx2B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 2hx2A-3lccA:
undetectable
2hx2B-3lccA:
undetectable		 2hx2A-3lccA:
17.86
2hx2B-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 ASP A  80
ASP A 138
ASP A  48
GLY A  74
 None
None
None
SAH  A 300 (-3.5A)
 1.42A 2igtC-3lccA:
9.7		 2igtC-3lccA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 2nseA-3lccA:
undetectable
2nseB-3lccA:
undetectable		 2nseA-3lccA:
18.00
2nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  74
GLY A  76
ASP A 123
VAL A 124
VAL A 140
 SAH  A 300 (-3.5A)
SAH  A 300 (-3.5A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
SAH  A 300 (-4.2A)
 1.05A 2qe6B-3lccA:
11.9		 2qe6B-3lccA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 141
GLY A  76
ILE A  96
ASP A 123
VAL A 124
 SAH  A 300 (-4.6A)
SAH  A 300 (-3.5A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
 0.79A 2zzmA-3lccA:
14.4		 2zzmA-3lccA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 141
GLY A  76
ILE A  96
ASP A 123
VAL A 124
 SAH  A 300 (-4.6A)
SAH  A 300 (-3.5A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
 0.76A 2zznA-3lccA:
14.9		 2zznA-3lccA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		6 / 10 PHE A 141
ASP A  95
ILE A  96
ALA A 100
ASP A 123
VAL A 124
 SAH  A 300 (-4.6A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 ( 4.4A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
 0.84A 3ay0A-3lccA:
undetectable		 3ay0A-3lccA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		6 / 10 PHE A 141
GLY A  76
ASP A  95
ILE A  96
ASP A 123
VAL A 124
 SAH  A 300 (-4.6A)
SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
 0.79A 3ay0B-3lccA:
14.6		 3ay0B-3lccA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.25A 3dqrA-3lccA:
undetectable
3dqrB-3lccA:
undetectable		 3dqrA-3lccA:
19.81
3dqrB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 3dqsA-3lccA:
undetectable
3dqsB-3lccA:
undetectable		 3dqsA-3lccA:
17.86
3dqsB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 3dqsA-3lccA:
0.0
3dqsB-3lccA:
0.0		 3dqsA-3lccA:
17.86
3dqsB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 3dqtA-3lccA:
1.4
3dqtB-3lccA:
undetectable		 3dqtA-3lccA:
17.86
3dqtB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 3dqtA-3lccA:
1.4
3dqtB-3lccA:
undetectable		 3dqtA-3lccA:
17.86
3dqtB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 3jwxA-3lccA:
undetectable
3jwxB-3lccA:
1.3		 3jwxA-3lccA:
18.00
3jwxB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 3jwxA-3lccA:
undetectable
3jwxB-3lccA:
1.2		 3jwxA-3lccA:
18.00
3jwxB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 3jwyA-3lccA:
undetectable
3jwyB-3lccA:
undetectable		 3jwyA-3lccA:
18.00
3jwyB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 3jwyA-3lccA:
0.0
3jwyB-3lccA:
0.0		 3jwyA-3lccA:
18.00
3jwyB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 3jwzA-3lccA:
0.5
3jwzB-3lccA:
undetectable		 3jwzA-3lccA:
18.00
3jwzB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 3jwzA-3lccA:
0.6
3jwzB-3lccA:
undetectable		 3jwzA-3lccA:
18.00
3jwzB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 3jx2A-3lccA:
undetectable
3jx2B-3lccA:
undetectable		 3jx2A-3lccA:
19.81
3jx2B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 3jx3A-3lccA:
undetectable
3jx3B-3lccA:
undetectable		 3jx3A-3lccA:
19.81
3jx3B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 3jx3A-3lccA:
undetectable
3jx3B-3lccA:
undetectable		 3jx3A-3lccA:
19.81
3jx3B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 3jx5A-3lccA:
undetectable
3jx5B-3lccA:
undetectable		 3jx5A-3lccA:
19.81
3jx5B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.26A 3jx6A-3lccA:
undetectable
3jx6B-3lccA:
undetectable		 3jx6A-3lccA:
19.81
3jx6B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 3n5pA-3lccA:
undetectable
3n5pB-3lccA:
undetectable		 3n5pA-3lccA:
18.00
3n5pB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 3n5qA-3lccA:
0.0
3n5qB-3lccA:
0.0		 3n5qA-3lccA:
18.00
3n5qB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 3n5rA-3lccA:
undetectable
3n5rB-3lccA:
undetectable		 3n5rA-3lccA:
18.00
3n5rB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 3n5rA-3lccA:
undetectable
3n5rB-3lccA:
undetectable		 3n5rA-3lccA:
18.00
3n5rB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 3n5sA-3lccA:
undetectable
3n5sB-3lccA:
undetectable		 3n5sA-3lccA:
18.00
3n5sB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 3n5sA-3lccA:
undetectable
3n5sB-3lccA:
undetectable		 3n5sA-3lccA:
18.00
3n5sB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 3n5tA-3lccA:
undetectable
3n5tB-3lccA:
undetectable		 3n5tA-3lccA:
18.00
3n5tB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.24A 3n5tA-3lccA:
undetectable
3n5tB-3lccA:
undetectable		 3n5tA-3lccA:
18.00
3n5tB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 3n6eA-3lccA:
1.4
3n6eB-3lccA:
undetectable		 3n6eA-3lccA:
18.00
3n6eB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 3n6eA-3lccA:
1.4
3n6eB-3lccA:
undetectable		 3n6eA-3lccA:
18.00
3n6eB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 3n6fA-3lccA:
undetectable
3n6fB-3lccA:
1.5		 3n6fA-3lccA:
18.00
3n6fB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 3n6fA-3lccA:
undetectable
3n6fB-3lccA:
1.0		 3n6fA-3lccA:
18.00
3n6fB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 3n6gA-3lccA:
undetectable
3n6gB-3lccA:
undetectable		 3n6gA-3lccA:
18.00
3n6gB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 3n6gA-3lccA:
undetectable
3n6gB-3lccA:
undetectable		 3n6gA-3lccA:
18.00
3n6gB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 3nldA-3lccA:
1.0
3nldB-3lccA:
0.0		 3nldA-3lccA:
18.00
3nldB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.35A 3nleA-3lccA:
undetectable
3nleB-3lccA:
undetectable		 3nleA-3lccA:
18.00
3nleB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 3nleA-3lccA:
undetectable
3nleB-3lccA:
undetectable		 3nleA-3lccA:
18.00
3nleB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 3nlfA-3lccA:
undetectable
3nlfB-3lccA:
undetectable		 3nlfA-3lccA:
18.00
3nlfB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 3nlgA-3lccA:
undetectable
3nlgB-3lccA:
1.7		 3nlgA-3lccA:
18.00
3nlgB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 3nlgA-3lccA:
undetectable
3nlgB-3lccA:
1.7		 3nlgA-3lccA:
18.00
3nlgB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 3nlhA-3lccA:
undetectable
3nlhB-3lccA:
undetectable		 3nlhA-3lccA:
18.00
3nlhB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 3nlhA-3lccA:
undetectable
3nlhB-3lccA:
undetectable		 3nlhA-3lccA:
18.00
3nlhB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 3nliA-3lccA:
0.0
3nliB-3lccA:
0.0		 3nliA-3lccA:
18.00
3nliB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 3nliA-3lccA:
undetectable
3nliB-3lccA:
undetectable		 3nliA-3lccA:
18.00
3nliB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.26A 3nljA-3lccA:
undetectable
3nljB-3lccA:
undetectable		 3nljA-3lccA:
19.81
3nljB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 3nlpA-3lccA:
undetectable
3nlpB-3lccA:
undetectable		 3nlpA-3lccA:
19.81
3nlpB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 3nlqA-3lccA:
undetectable
3nlqB-3lccA:
undetectable		 3nlqA-3lccA:
19.81
3nlqB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 3nluA-3lccA:
undetectable
3nluB-3lccA:
undetectable		 3nluA-3lccA:
18.00
3nluB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 3nosA-3lccA:
0.0
3nosB-3lccA:
0.0		 3nosA-3lccA:
18.52
3nosB-3lccA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 3nosA-3lccA:
0.0
3nosB-3lccA:
0.0		 3nosA-3lccA:
18.52
3nosB-3lccA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 GLY A  76
ASP A  95
ASP A 123
 SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-3.8A)
 0.43A 3ou7C-3lccA:
15.7		 3ou7C-3lccA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 3pnhA-3lccA:
0.0
3pnhB-3lccA:
0.0		 3pnhA-3lccA:
17.86
3pnhB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 3pnhA-3lccA:
undetectable
3pnhB-3lccA:
undetectable		 3pnhA-3lccA:
17.86
3pnhB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 3rqoA-3lccA:
0.0
3rqoB-3lccA:
0.0		 3rqoA-3lccA:
18.04
3rqoB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.26A 3rqoA-3lccA:
undetectable
3rqoB-3lccA:
undetectable		 3rqoA-3lccA:
18.04
3rqoB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 3rqpA-3lccA:
undetectable
3rqpB-3lccA:
undetectable		 3rqpA-3lccA:
18.04
3rqpB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 LEU A 167
ALA A 154
THR A 169
PHE A 142
 None
 1.32A 3vasB-3lccA:
2.6		 3vasB-3lccA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 4c3aA-3lccA:
undetectable
4c3aB-3lccA:
undetectable		 4c3aA-3lccA:
18.04
4c3aB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 4c3aA-3lccA:
undetectable
4c3aB-3lccA:
undetectable		 4c3aA-3lccA:
18.04
4c3aB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4carA-3lccA:
undetectable
4carB-3lccA:
undetectable		 4carA-3lccA:
18.04
4carB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4carA-3lccA:
undetectable
4carB-3lccA:
undetectable		 4carA-3lccA:
18.04
4carB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 4cftA-3lccA:
undetectable
4cftB-3lccA:
1.0		 4cftA-3lccA:
18.04
4cftB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4cftA-3lccA:
undetectable
4cftB-3lccA:
1.0		 4cftA-3lccA:
18.04
4cftB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 4ctyA-3lccA:
undetectable
4ctyB-3lccA:
1.2		 4ctyA-3lccA:
18.04
4ctyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4ctyA-3lccA:
undetectable
4ctyB-3lccA:
1.1		 4ctyA-3lccA:
18.04
4ctyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 4ctzA-3lccA:
1.8
4ctzB-3lccA:
undetectable		 4ctzA-3lccA:
18.04
4ctzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4ctzA-3lccA:
1.8
4ctzB-3lccA:
0.0		 4ctzA-3lccA:
18.04
4ctzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 4cu0A-3lccA:
undetectable
4cu0B-3lccA:
undetectable		 4cu0A-3lccA:
18.04
4cu0B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4cu0A-3lccA:
undetectable
4cu0B-3lccA:
undetectable		 4cu0A-3lccA:
18.04
4cu0B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4cu1A-3lccA:
undetectable
4cu1B-3lccA:
undetectable		 4cu1A-3lccA:
18.04
4cu1B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4cu1A-3lccA:
undetectable
4cu1B-3lccA:
undetectable		 4cu1A-3lccA:
18.04
4cu1B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 4cwvA-3lccA:
1.4
4cwvB-3lccA:
undetectable		 4cwvA-3lccA:
18.04
4cwvB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 4cwvA-3lccA:
1.5
4cwvB-3lccA:
undetectable		 4cwvA-3lccA:
18.04
4cwvB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4cwwA-3lccA:
1.2
4cwwB-3lccA:
undetectable		 4cwwA-3lccA:
18.04
4cwwB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4cwwA-3lccA:
1.2
4cwwB-3lccA:
undetectable		 4cwwA-3lccA:
18.04
4cwwB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.37A 4cwxA-3lccA:
undetectable
4cwxB-3lccA:
undetectable		 4cwxA-3lccA:
18.04
4cwxB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 4cwxA-3lccA:
undetectable
4cwxB-3lccA:
undetectable		 4cwxA-3lccA:
18.04
4cwxB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 4cwyA-3lccA:
1.0
4cwyB-3lccA:
1.3		 4cwyA-3lccA:
18.04
4cwyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.36A 4cwyA-3lccA:
1.0
4cwyB-3lccA:
1.0		 4cwyA-3lccA:
18.04
4cwyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4cwzA-3lccA:
undetectable
4cwzB-3lccA:
undetectable		 4cwzA-3lccA:
18.04
4cwzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 4cwzA-3lccA:
undetectable
4cwzB-3lccA:
undetectable		 4cwzA-3lccA:
18.04
4cwzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 4cx0A-3lccA:
undetectable
4cx0B-3lccA:
undetectable		 4cx0A-3lccA:
18.04
4cx0B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4cx0A-3lccA:
undetectable
4cx0B-3lccA:
undetectable		 4cx0A-3lccA:
18.04
4cx0B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 4cx3A-3lccA:
undetectable
4cx3B-3lccA:
undetectable		 4cx3A-3lccA:
19.81
4cx3B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 4cx3A-3lccA:
undetectable
4cx3B-3lccA:
undetectable		 4cx3A-3lccA:
19.81
4cx3B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 4cx4A-3lccA:
undetectable
4cx4B-3lccA:
undetectable		 4cx4A-3lccA:
19.81
4cx4B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 4cx4A-3lccA:
undetectable
4cx4B-3lccA:
undetectable		 4cx4A-3lccA:
19.81
4cx4B-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 4d1oA-3lccA:
undetectable
4d1oB-3lccA:
undetectable		 4d1oA-3lccA:
17.98
4d1oB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4d1oA-3lccA:
undetectable
4d1oB-3lccA:
undetectable		 4d1oA-3lccA:
17.98
4d1oB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4d1pA-3lccA:
undetectable
4d1pB-3lccA:
undetectable		 4d1pA-3lccA:
17.98
4d1pB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 4d34A-3lccA:
undetectable
4d34B-3lccA:
undetectable		 4d34A-3lccA:
18.04
4d34B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4d34A-3lccA:
undetectable
4d34B-3lccA:
undetectable		 4d34A-3lccA:
18.04
4d34B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4d36A-3lccA:
undetectable
4d36B-3lccA:
undetectable		 4d36A-3lccA:
18.04
4d36B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 4d36A-3lccA:
undetectable
4d36B-3lccA:
undetectable		 4d36A-3lccA:
18.04
4d36B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 4d37A-3lccA:
undetectable
4d37B-3lccA:
undetectable		 4d37A-3lccA:
18.04
4d37B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4d38A-3lccA:
undetectable
4d38B-3lccA:
undetectable		 4d38A-3lccA:
18.04
4d38B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.36A 4d38A-3lccA:
undetectable
4d38B-3lccA:
undetectable		 4d38A-3lccA:
18.04
4d38B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4d39A-3lccA:
undetectable
4d39B-3lccA:
undetectable		 4d39A-3lccA:
18.04
4d39B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4d3aA-3lccA:
undetectable
4d3aB-3lccA:
undetectable		 4d3aA-3lccA:
18.04
4d3aB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4imxA-3lccA:
undetectable
4imxB-3lccA:
undetectable		 4imxA-3lccA:
17.86
4imxB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 4imxA-3lccA:
0.0
4imxB-3lccA:
0.0		 4imxA-3lccA:
17.86
4imxB-3lccA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  74
GLY A  76
ASP A  95
ILE A  96
ASP A 123
 SAH  A 300 (-3.5A)
SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
 0.55A 4iv8A-3lccA:
16.3		 4iv8A-3lccA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  74
GLY A  76
ASP A  95
ILE A  96
ASP A 123
 SAH  A 300 (-3.5A)
SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
 0.56A 4iv8B-3lccA:
16.4		 4iv8B-3lccA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4jskA-3lccA:
undetectable
4jskB-3lccA:
undetectable		 4jskA-3lccA:
18.04
4jskB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4jslA-3lccA:
undetectable
4jslB-3lccA:
undetectable		 4jslA-3lccA:
18.04
4jslB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 4jslA-3lccA:
undetectable
4jslB-3lccA:
undetectable		 4jslA-3lccA:
18.04
4jslB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4jsmA-3lccA:
undetectable
4jsmB-3lccA:
undetectable		 4jsmA-3lccA:
18.04
4jsmB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4jsmA-3lccA:
undetectable
4jsmB-3lccA:
undetectable		 4jsmA-3lccA:
18.04
4jsmB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.36A 4k5hA-3lccA:
undetectable
4k5hB-3lccA:
undetectable		 4k5hA-3lccA:
18.04
4k5hB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4k5hA-3lccA:
undetectable
4k5hB-3lccA:
undetectable		 4k5hA-3lccA:
18.04
4k5hB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4k5iA-3lccA:
undetectable
4k5iB-3lccA:
undetectable		 4k5iA-3lccA:
18.04
4k5iB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4k5iA-3lccA:
undetectable
4k5iB-3lccA:
undetectable		 4k5iA-3lccA:
18.04
4k5iB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 4k5jA-3lccA:
undetectable
4k5jB-3lccA:
undetectable		 4k5jA-3lccA:
18.04
4k5jB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4k5jA-3lccA:
undetectable
4k5jB-3lccA:
undetectable		 4k5jA-3lccA:
18.04
4k5jB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.35A 4k5kA-3lccA:
undetectable
4k5kB-3lccA:
undetectable		 4k5kA-3lccA:
18.04
4k5kB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 4k5kA-3lccA:
undetectable
4k5kB-3lccA:
undetectable		 4k5kA-3lccA:
18.04
4k5kB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.35A 4kcpA-3lccA:
undetectable
4kcpB-3lccA:
1.3		 4kcpA-3lccA:
18.04
4kcpB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4kcpA-3lccA:
undetectable
4kcpB-3lccA:
1.2		 4kcpA-3lccA:
18.04
4kcpB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 4kcqA-3lccA:
1.5
4kcqB-3lccA:
undetectable		 4kcqA-3lccA:
18.04
4kcqB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4kcqA-3lccA:
1.5
4kcqB-3lccA:
undetectable		 4kcqA-3lccA:
18.04
4kcqB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4kcrA-3lccA:
undetectable
4kcrB-3lccA:
undetectable		 4kcrA-3lccA:
18.04
4kcrB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4kcrA-3lccA:
undetectable
4kcrB-3lccA:
undetectable		 4kcrA-3lccA:
18.04
4kcrB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 4kcsA-3lccA:
undetectable
4kcsB-3lccA:
undetectable		 4kcsA-3lccA:
18.04
4kcsB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4kcsA-3lccA:
undetectable
4kcsB-3lccA:
undetectable		 4kcsA-3lccA:
18.04
4kcsB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4luwA-3lccA:
undetectable
4luwB-3lccA:
undetectable		 4luwA-3lccA:
18.08
4luwB-3lccA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4luwA-3lccA:
0.0
4luwB-3lccA:
0.0		 4luwA-3lccA:
18.08
4luwB-3lccA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 4uh7A-3lccA:
1.0
4uh7B-3lccA:
1.2		 4uh7A-3lccA:
18.04
4uh7B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 4uh7A-3lccA:
1.0
4uh7B-3lccA:
1.2		 4uh7A-3lccA:
18.04
4uh7B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4uh8A-3lccA:
undetectable
4uh8B-3lccA:
undetectable		 4uh8A-3lccA:
18.04
4uh8B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 4uh8A-3lccA:
undetectable
4uh8B-3lccA:
undetectable		 4uh8A-3lccA:
18.04
4uh8B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 4uh9A-3lccA:
undetectable
4uh9B-3lccA:
undetectable		 4uh9A-3lccA:
18.04
4uh9B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 4uh9A-3lccA:
undetectable
4uh9B-3lccA:
undetectable		 4uh9A-3lccA:
18.04
4uh9B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 4uhaA-3lccA:
undetectable
4uhaB-3lccA:
1.4		 4uhaA-3lccA:
18.04
4uhaB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 4uhaA-3lccA:
undetectable
4uhaB-3lccA:
1.4		 4uhaA-3lccA:
18.04
4uhaB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4upqA-3lccA:
undetectable
4upqB-3lccA:
1.3		 4upqA-3lccA:
18.04
4upqB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 4upqA-3lccA:
undetectable
4upqB-3lccA:
1.3		 4upqA-3lccA:
18.04
4upqB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4uprA-3lccA:
undetectable
4uprB-3lccA:
undetectable		 4uprA-3lccA:
18.04
4uprB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4uprA-3lccA:
undetectable
4uprB-3lccA:
undetectable		 4uprA-3lccA:
18.04
4uprB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 4upsA-3lccA:
undetectable
4upsB-3lccA:
undetectable		 4upsA-3lccA:
18.04
4upsB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 4upsA-3lccA:
undetectable
4upsB-3lccA:
undetectable		 4upsA-3lccA:
18.04
4upsB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 4uptA-3lccA:
undetectable
4uptB-3lccA:
undetectable		 4uptA-3lccA:
18.04
4uptB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 4uptA-3lccA:
undetectable
4uptB-3lccA:
undetectable		 4uptA-3lccA:
18.04
4uptB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 220
GLY A 221
GLU A 166
ILE A  56
MET A  84
 None
 1.36A 4x3mA-3lccA:
undetectable		 4x3mA-3lccA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 5addA-3lccA:
undetectable
5addB-3lccA:
undetectable		 5addA-3lccA:
19.81
5addB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 5adeA-3lccA:
undetectable
5adeB-3lccA:
undetectable		 5adeA-3lccA:
19.81
5adeB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 5adjA-3lccA:
undetectable
5adjB-3lccA:
undetectable		 5adjA-3lccA:
18.04
5adjB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 5adjA-3lccA:
undetectable
5adjB-3lccA:
undetectable		 5adjA-3lccA:
18.04
5adjB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5adkA-3lccA:
undetectable
5adkB-3lccA:
undetectable		 5adkA-3lccA:
18.04
5adkB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 5adkA-3lccA:
undetectable
5adkB-3lccA:
undetectable		 5adkA-3lccA:
18.04
5adkB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.32A 5adlA-3lccA:
undetectable
5adlB-3lccA:
1.4		 5adlA-3lccA:
18.04
5adlB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 5adlA-3lccA:
undetectable
5adlB-3lccA:
1.7		 5adlA-3lccA:
18.04
5adlB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 5admA-3lccA:
undetectable
5admB-3lccA:
undetectable		 5admA-3lccA:
18.04
5admB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5admA-3lccA:
undetectable
5admB-3lccA:
undetectable		 5admA-3lccA:
18.04
5admB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5adnA-3lccA:
1.7
5adnB-3lccA:
undetectable		 5adnA-3lccA:
18.04
5adnB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 ALA A 144
VAL A 140
TYR A 172
VAL A  23
 SAH  A 300 ( 3.9A)
SAH  A 300 (-4.2A)
None
None
 1.03A 5eckD-3lccA:
undetectable		 5eckD-3lccA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 ALA A 144
VAL A 140
TYR A 172
VAL A  23
 SAH  A 300 ( 3.9A)
SAH  A 300 (-4.2A)
None
None
 0.97A 5eclA-3lccA:
undetectable		 5eclA-3lccA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 5fj2A-3lccA:
undetectable
5fj2B-3lccA:
undetectable		 5fj2A-3lccA:
18.04
5fj2B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5fj2A-3lccA:
undetectable
5fj2B-3lccA:
undetectable		 5fj2A-3lccA:
18.04
5fj2B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.30A 5fj3A-3lccA:
undetectable
5fj3B-3lccA:
undetectable		 5fj3A-3lccA:
18.04
5fj3B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 5fj3A-3lccA:
undetectable
5fj3B-3lccA:
undetectable		 5fj3A-3lccA:
18.04
5fj3B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5fvyA-3lccA:
undetectable
5fvyB-3lccA:
undetectable		 5fvyA-3lccA:
18.04
5fvyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 5fvyA-3lccA:
undetectable
5fvyB-3lccA:
undetectable		 5fvyA-3lccA:
18.04
5fvyB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 5fvzA-3lccA:
undetectable
5fvzB-3lccA:
undetectable		 5fvzA-3lccA:
18.04
5fvzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5fvzA-3lccA:
undetectable
5fvzB-3lccA:
undetectable		 5fvzA-3lccA:
18.04
5fvzB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 5g0pA-3lccA:
undetectable
5g0pB-3lccA:
undetectable		 5g0pA-3lccA:
19.81
5g0pB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 5g0pA-3lccA:
undetectable
5g0pB-3lccA:
undetectable		 5g0pA-3lccA:
19.81
5g0pB-3lccA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 PHE A 141
GLY A  76
ILE A  96
ASP A 123
VAL A 124
 SAH  A 300 (-4.6A)
SAH  A 300 (-3.5A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
SAH  A 300 (-4.1A)
 0.77A 5hjiA-3lccA:
13.0		 5hjiA-3lccA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  76
HIS A  79
VAL A  81
ILE A 145
ALA A 144
 SAH  A 300 (-3.5A)
None
None
None
SAH  A 300 ( 3.9A)
 1.11A 5n0xA-3lccA:
undetectable		 5n0xA-3lccA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  76
PHE A 137
VAL A  81
ILE A 145
ALA A 144
 SAH  A 300 (-3.5A)
None
None
None
SAH  A 300 ( 3.9A)
 1.04A 5n0xA-3lccA:
undetectable		 5n0xA-3lccA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.23A 5uo8A-3lccA:
undetectable
5uo8B-3lccA:
undetectable		 5uo8A-3lccA:
17.98
5uo8B-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 5uo8C-3lccA:
undetectable
5uo8D-3lccA:
undetectable		 5uo8C-3lccA:
17.98
5uo8D-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5uo8C-3lccA:
undetectable
5uo8D-3lccA:
undetectable		 5uo8C-3lccA:
17.98
5uo8D-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.35A 5uo9A-3lccA:
undetectable
5uo9B-3lccA:
undetectable		 5uo9A-3lccA:
17.98
5uo9B-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 5uo9A-3lccA:
undetectable
5uo9B-3lccA:
undetectable		 5uo9A-3lccA:
17.98
5uo9B-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 5uo9C-3lccA:
undetectable
5uo9D-3lccA:
undetectable		 5uo9C-3lccA:
17.98
5uo9D-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.28A 5uo9C-3lccA:
undetectable
5uo9D-3lccA:
undetectable		 5uo9C-3lccA:
17.98
5uo9D-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 5uodA-3lccA:
undetectable
5uodB-3lccA:
undetectable		 5uodA-3lccA:
18.04
5uodB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5uodA-3lccA:
undetectable
5uodB-3lccA:
undetectable		 5uodA-3lccA:
18.04
5uodB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5vv6A-3lccA:
undetectable
5vv6B-3lccA:
undetectable		 5vv6A-3lccA:
18.04
5vv6B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 5vv6A-3lccA:
undetectable
5vv6B-3lccA:
undetectable		 5vv6A-3lccA:
18.04
5vv6B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 5vv7A-3lccA:
undetectable
5vv7B-3lccA:
1.0		 5vv7A-3lccA:
18.04
5vv7B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 5vv7A-3lccA:
undetectable
5vv7B-3lccA:
1.0		 5vv7A-3lccA:
18.04
5vv7B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5vv8A-3lccA:
undetectable
5vv8B-3lccA:
undetectable		 5vv8A-3lccA:
18.04
5vv8B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 5vv8A-3lccA:
undetectable
5vv8B-3lccA:
undetectable		 5vv8A-3lccA:
18.04
5vv8B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 5vv9A-3lccA:
undetectable
5vv9B-3lccA:
undetectable		 5vv9A-3lccA:
18.04
5vv9B-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.33A 5vvaA-3lccA:
undetectable
5vvaB-3lccA:
undetectable		 5vvaA-3lccA:
18.04
5vvaB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 5vvaA-3lccA:
0.0
5vvaB-3lccA:
0.0		 5vvaA-3lccA:
18.04
5vvaB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 5vvbA-3lccA:
undetectable
5vvbB-3lccA:
undetectable		 5vvbA-3lccA:
17.98
5vvbB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 5vvbC-3lccA:
0.0
5vvbD-3lccA:
0.0		 5vvbC-3lccA:
17.98
5vvbD-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 5vvcA-3lccA:
undetectable
5vvcB-3lccA:
undetectable		 5vvcA-3lccA:
17.98
5vvcB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.27A 5vvcC-3lccA:
undetectable
5vvcD-3lccA:
undetectable		 5vvcC-3lccA:
17.98
5vvcD-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 5vvcC-3lccA:
undetectable
5vvcD-3lccA:
undetectable		 5vvcC-3lccA:
17.98
5vvcD-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.30A 5vvdA-3lccA:
undetectable
5vvdB-3lccA:
undetectable		 5vvdA-3lccA:
17.98
5vvdB-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.25A 5vvdC-3lccA:
undetectable
5vvdD-3lccA:
undetectable		 5vvdC-3lccA:
17.98
5vvdD-3lccA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5vvgA-3lccA:
undetectable
5vvgB-3lccA:
undetectable		 5vvgA-3lccA:
18.04
5vvgB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 5vvgA-3lccA:
undetectable
5vvgB-3lccA:
undetectable		 5vvgA-3lccA:
18.04
5vvgB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 5vvnA-3lccA:
undetectable
5vvnB-3lccA:
undetectable		 5vvnA-3lccA:
18.04
5vvnB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.35A 5vvnA-3lccA:
undetectable
5vvnB-3lccA:
undetectable		 5vvnA-3lccA:
18.04
5vvnB-3lccA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  74
GLY A  76
ASP A  95
ILE A  96
VAL A 124
 SAH  A 300 (-3.5A)
SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 (-4.1A)
 0.51A 5wy0A-3lccA:
13.5		 5wy0A-3lccA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 6av6A-3lccA:
undetectable
6av6B-3lccA:
undetectable		 6av6A-3lccA:
17.06
6av6B-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 6av6A-3lccA:
undetectable
6av6B-3lccA:
undetectable		 6av6A-3lccA:
17.06
6av6B-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 6av6C-3lccA:
undetectable
6av6D-3lccA:
undetectable		 6av6C-3lccA:
17.06
6av6D-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 6av6C-3lccA:
undetectable
6av6D-3lccA:
undetectable		 6av6C-3lccA:
17.06
6av6D-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.27A 6av7A-3lccA:
undetectable
6av7B-3lccA:
undetectable		 6av7A-3lccA:
17.06
6av7B-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.29A 6av7C-3lccA:
undetectable
6av7D-3lccA:
undetectable		 6av7C-3lccA:
17.06
6av7D-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 6av7C-3lccA:
undetectable
6av7D-3lccA:
undetectable		 6av7C-3lccA:
17.06
6av7D-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  74
ASP A  95
ILE A  96
ASP A 123
ALA A 144
 SAH  A 300 (-3.5A)
SAH  A 300 (-2.8A)
SAH  A 300 (-4.2A)
SAH  A 300 (-3.8A)
SAH  A 300 ( 3.9A)
 0.73A 6bq4A-3lccA:
11.3		 6bq4A-3lccA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.34A 6cieA-3lccA:
undetectable
6cieB-3lccA:
undetectable		 6cieA-3lccA:
17.06
6cieB-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.31A 6cieA-3lccA:
undetectable
6cieB-3lccA:
undetectable		 6cieA-3lccA:
17.06
6cieB-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.32A 6cieC-3lccA:
0.0
6cieD-3lccA:
0.0		 6cieC-3lccA:
17.06
6cieD-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.29A 6cifA-3lccA:
undetectable
6cifB-3lccA:
undetectable		 6cifA-3lccA:
17.06
6cifB-3lccA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 SER A 111
ALA A  85
ILE A  56
ALA A  52
 None
 0.86A 6ma7A-3lccA:
undetectable		 6ma7A-3lccA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.28A 8nseA-3lccA:
undetectable
8nseB-3lccA:
undetectable		 8nseA-3lccA:
18.00
8nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.33A 8nseA-3lccA:
undetectable
8nseB-3lccA:
undetectable		 8nseA-3lccA:
18.00
8nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 120
ARG A  69
PHE A 133
GLU A 122
 None
 1.31A 9nseA-3lccA:
undetectable
9nseB-3lccA:
undetectable		 9nseA-3lccA:
18.00
9nseB-3lccA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3lcc PUTATIVE METHYL
CHLORIDE TRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 133
GLU A 122
VAL A 120
ARG A  69
 None
 1.34A 9nseA-3lccA:
undetectable
9nseB-3lccA:
undetectable		 9nseA-3lccA:
18.00
9nseB-3lccA:
18.00