SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ld2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		5 / 12 GLY A  93
ILE A  99
ALA A  52
GLY A  60
ILE A   3
 COA  A 164 (-3.3A)
None
None
None
None
 0.92A 1bx4A-3ld2A:
undetectable		 1bx4A-3ld2A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		5 / 12 LEU A 101
LEU A  50
LEU A  62
GLY A  80
PHE A 131
 None
None
None
COA  A 164 ( 4.4A)
None
 1.40A 1d4fD-3ld2A:
undetectable		 1d4fD-3ld2A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		4 / 7 PHE A  79
LEU A 129
VAL A 115
ILE A 113
 None
 0.93A 1t87B-3ld2A:
undetectable		 1t87B-3ld2A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		3 / 3 ALA A  95
ARG A  94
LYS A 128
 None
None
COA  A 164 (-2.9A)
 1.04A 3kp3B-3ld2A:
undetectable		 3kp3B-3ld2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		5 / 12 GLU A  12
VAL A  61
ILE A  58
GLN A  13
ILE A  11
 None
 1.46A 4a99A-3ld2A:
undetectable
4a99C-3ld2A:
undetectable		 4a99A-3ld2A:
24.67
4a99C-3ld2A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		4 / 8 PHE A  79
LEU A 129
VAL A 115
ILE A 113
 None
 0.90A 4l4cB-3ld2A:
undetectable		 4l4cB-3ld2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ld2 PUTATIVE
ACETYLTRANSFERASE
(Streptococcus
mutans) 		5 / 9 LEU A 101
PHE A 100
GLU A 103
LEU A  62
VAL A 111
 None
 1.19A 6ftpA-3ld2A:
undetectable
6ftpB-3ld2A:
undetectable		 6ftpA-3ld2A:
24.14
6ftpB-3ld2A:
11.98