SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ld3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
3 / 3 LYS A 149
ARG A  44
ASP A  68
PO4  A 200 ( 4.9A)
PO4  A 200 (-3.2A)
None
1.44A 3o7wA-3ld3A:
undetectable
3o7wA-3ld3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
3 / 3 ARG A  77
PHE A  78
PRO A  79
None
0.58A 3zoaB-3ld3A:
undetectable
3zoaB-3ld3A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
4 / 8 TYR A 142
TYR A  52
VAL A  93
ILE A 135
PO4  A 200 (-4.6A)
None
None
None
1.12A 4aftD-3ld3A:
undetectable
4aftE-3ld3A:
undetectable
4aftD-3ld3A:
23.11
4aftE-3ld3A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
5 / 12 THR A  62
GLY A   9
GLY A   7
ASN A  61
ALA A 111
None
1.14A 4uckB-3ld3A:
undetectable
4uckB-3ld3A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
3 / 3 TYR A 142
ARG A  44
LYS A 143
PO4  A 200 (-4.6A)
PO4  A 200 (-3.2A)
PO4  A 200 (-2.7A)
1.34A 4wq5B-3ld3A:
undetectable
4wq5B-3ld3A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
4 / 7 GLU A 146
GLU A  99
ASP A  98
TYR A 142
None
PO4  A 200 ( 4.9A)
None
PO4  A 200 (-4.6A)
1.13A 4zz8A-3ld3A:
undetectable
4zz8A-3ld3A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
5 / 12 ASP A  34
PRO A  69
GLY A  57
GLU A  21
GLU A  32
None
None
None
None
PO4  A 200 ( 4.6A)
1.07A 5hfjA-3ld3A:
undetectable
5hfjA-3ld3A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
3ld3 INORGANIC
PYROPHOSPHATASE

(Anaplasma
phagocytophilum)
5 / 12 ASP A  34
PRO A  69
GLY A  57
GLU A  21
GLU A  32
None
None
None
None
PO4  A 200 ( 4.6A)
1.08A 5hfjD-3ld3A:
undetectable
5hfjD-3ld3A:
24.28