SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ld9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3ld9	THYMIDYLATE KINASE (Ehrlichia chaffeensis)	4 / 5	SER A 11 GLY A 7 HIS A 192 ASP A 92	SO4 A 300 (-4.6A) None None SO4 A 300 ( 4.7A)	1.06A	2oxtB-3ld9A: undetectable	2oxtB-3ld9A: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3ld9	THYMIDYLATE KINASE (Ehrlichia chaffeensis)	4 / 4	SER A 11 GLY A 12 HIS A 174 ASP A 126	SO4 A 300 (-4.6A) SO4 A 300 (-3.4A) None None	1.33A	2oxtC-3ld9A: undetectable	2oxtC-3ld9A: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KL3_A_DHIA403_0 (GLUCURONOXYLANASE XYNC)	3ld9	THYMIDYLATE KINASE (Ehrlichia chaffeensis)	4 / 4	GLY A 105 TYR A 104 GLY A 161 ASP A 160	None	0.94A	3kl3A-3ld9A: undetectable	3kl3A-3ld9A: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_2 (CYCLIN-DEPENDENT KINASE 8)	3ld9	THYMIDYLATE KINASE (Ehrlichia chaffeensis)	4 / 7	LEU A 83 VAL A 89 VAL A 123 LEU A 20	None	0.94A	3rgfA-3ld9A: undetectable	3rgfA-3ld9A: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UY4_A_PAUA302_0 (PANTOTHENATE SYNTHETASE)	3ld9	THYMIDYLATE KINASE (Ehrlichia chaffeensis)	4 / 8	GLN A 16 VAL A 191 VAL A 195 ASP A 186	None	1.09A	3uy4A-3ld9A: undetectable	3uy4A-3ld9A: 21.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OXT_B_SAMB300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3ld9","THYMIDYLATE KINASE","Ehrlichia chaffeensis",4,"SER A  11;GLY A   7;HIS A 192;ASP A  92","SO4 A 300 (-4.6A);None;None;SO4 A 300 ( 4.7A)","1.06A","2oxtB-3ld9A:undetectable","2oxtB-3ld9A:20.29"],["2OXT_C_SAMC300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3ld9","THYMIDYLATE KINASE","Ehrlichia chaffeensis",4,"SER A  11;GLY A  12;HIS A 174;ASP A 126","SO4 A 300 (-4.6A);SO4 A 300 (-3.4A);None;None","1.33A","2oxtC-3ld9A:undetectable","2oxtC-3ld9A:20.29"],["3KL3_A_DHIA403_0","GLUCURONOXYLANASE XYNC","3ld9","THYMIDYLATE KINASE","Ehrlichia chaffeensis",4,"GLY A 105;TYR A 104;GLY A 161;ASP A 160","None","0.94A","3kl3A-3ld9A:undetectable","3kl3A-3ld9A:19.40"],["3RGF_A_BAXA465_2","CYCLIN-DEPENDENT KINASE 8","3ld9","THYMIDYLATE KINASE","Ehrlichia chaffeensis",4,"LEU A  83;VAL A  89;VAL A 123;LEU A  20","None","0.94A","3rgfA-3ld9A:undetectable","3rgfA-3ld9A:20.67"],["3UY4_A_PAUA302_0","PANTOTHENATE SYNTHETASE","3ld9","THYMIDYLATE KINASE","Ehrlichia chaffeensis",4,"GLN A  16;VAL A 191;VAL A 195;ASP A 186","None","1.09A","3uy4A-3ld9A:undetectable","3uy4A-3ld9A:21.66"]]