SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ldo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.09A 1gfzA-3ldoA:
undetectable
1gfzA-3ldoA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 5 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.14A 1kiaB-3ldoA:
undetectable
1kiaB-3ldoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.16A 1kiaC-3ldoA:
undetectable
1kiaC-3ldoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.10A 1l5qA-3ldoA:
undetectable
1l5qA-3ldoA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.06A 1l7xA-3ldoA:
undetectable
1l7xA-3ldoA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.09A 1l7xB-3ldoA:
undetectable
1l7xB-3ldoA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 5 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.14A 1nbhB-3ldoA:
1.2
1nbhB-3ldoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 ILE A 371
GLY A 254
GLY A 227
LEU A 334
LEU A 253
None
None
ANP  A 408 (-3.4A)
None
None
1.10A 1rjdB-3ldoA:
undetectable
1rjdB-3ldoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 ILE A 371
GLY A 254
GLY A 227
LEU A 334
LEU A 253
None
None
ANP  A 408 (-3.4A)
None
None
1.09A 1rjdC-3ldoA:
undetectable
1rjdC-3ldoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
3 / 3 ASP A 357
VAL A 360
PRO A 202
None
0.74A 2avvA-3ldoA:
undetectable
2avvA-3ldoA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 LEU A  98
VAL A 108
ILE A 112
ILE A 128
None
0.86A 2piwA-3ldoA:
undetectable
2piwA-3ldoA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASP A 224
VAL A 362
PRO A 173
THR A 171
None
1.27A 2q6oB-3ldoA:
undetectable
2q6oB-3ldoA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 5 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.14A 3bcrA-3ldoA:
undetectable
3bcrA-3ldoA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.12A 3dd1A-3ldoA:
undetectable
3dd1A-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.09A 3dd1B-3ldoA:
undetectable
3dd1B-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.11A 3ddsA-3ldoA:
undetectable
3ddsA-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.09A 3ddsB-3ldoA:
undetectable
3ddsB-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.12A 3ddwA-3ldoA:
undetectable
3ddwA-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.11A 3ddwB-3ldoA:
undetectable
3ddwB-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 GLY A 363
GLY A 364
GLY A 255
ASP A 257
ARG A 297
ANP  A 408 (-3.2A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.4A)
None
None
0.98A 3huoB-3ldoA:
undetectable
3huoB-3ldoA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 5 ASP A 257
GLU A 256
GLY A 228
ASP A 250
None
None
ANP  A 408 (-3.6A)
None
1.39A 3w9tD-3ldoA:
undetectable
3w9tD-3ldoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 5 GLU A 316
GLY A 315
TYR A 313
ASP A 281
None
1.20A 3w9tD-3ldoA:
undetectable
3w9tD-3ldoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
3 / 3 VAL A  66
GLY A  77
LYS A  81
None
0.73A 4k50A-3ldoA:
undetectable
4k50A-3ldoA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
3 / 3 VAL A  66
GLY A  77
LYS A  81
None
0.71A 4k50I-3ldoA:
undetectable
4k50I-3ldoA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 ASP A 231
ALA A 206
VAL A 360
SER A 233
THR A 171
None
1.13A 4mm4B-3ldoA:
undetectable
4mm4B-3ldoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 GLY A  58
ARG A 290
THR A 156
ILE A  53
VAL A  42
None
1.34A 4okwA-3ldoA:
undetectable
4okwA-3ldoA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 7 GLU A 201
THR A  37
GLY A  36
THR A  38
None
ANP  A 408 (-3.4A)
ANP  A 408 (-3.2A)
ANP  A 408 (-2.8A)
0.95A 4qwpB-3ldoA:
undetectable
4qwpB-3ldoA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 6 LEU A  98
LYS A 125
PRO A 126
GLU A 143
None
1.14A 4z4gA-3ldoA:
6.4
4z4gA-3ldoA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 226
GLY A 255
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.04A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 226
GLY A 255
LYS A 296
SER A 300
SER A 365
ARG A 367
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.9A)
ANP  A 408 (-4.8A)
1.14A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
8 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
0.52A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 10 GLY A 227
GLY A 255
GLY A 364
SER A 365
ILE A 371
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
None
0.99A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.33A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 255
GLU A 293
LYS A 296
SER A 300
SER A 365
ARG A 367
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.9A)
ANP  A 408 (-4.8A)
0.84A 5aqfA-3ldoA:
53.7
5aqfA-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
6 / 10 GLY A 226
GLY A 255
LYS A 296
SER A 300
ARG A 367
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-4.9A)
ANP  A 408 (-4.8A)
1.15A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 226
GLY A 255
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.05A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
8 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
0.52A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 10 GLY A 227
GLY A 255
GLY A 364
SER A 365
ILE A 371
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
None
0.98A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.33A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
6 / 10 GLY A 255
GLU A 293
LYS A 296
SER A 300
ARG A 367
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-4.9A)
ANP  A 408 (-4.8A)
0.88A 5aqfC-3ldoA:
53.3
5aqfC-3ldoA:
69.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 226
GLY A 255
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.02A 5aqyA-3ldoA:
56.3
5aqyA-3ldoA:
66.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
8 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
SER A 300
GLY A 364
SER A 365
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
0.53A 5aqyA-3ldoA:
56.3
5aqyA-3ldoA:
66.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 10 GLY A 227
GLY A 255
GLY A 364
SER A 365
ILE A 371
ANP  A 408 (-3.4A)
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-3.9A)
None
0.99A 5aqyA-3ldoA:
56.3
5aqyA-3ldoA:
66.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ANP  A 408 (-3.4A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.8A)
1.35A 5aqyA-3ldoA:
56.3
5aqyA-3ldoA:
66.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
7 / 10 GLY A 255
GLU A 293
LYS A 296
SER A 300
SER A 365
ARG A 367
ILE A 368
ANP  A 408 (-3.4A)
ANP  A 408 (-2.5A)
ANP  A 408 (-3.1A)
ANP  A 408 (-2.6A)
ANP  A 408 (-3.9A)
ANP  A 408 (-4.9A)
ANP  A 408 (-4.8A)
0.86A 5aqyA-3ldoA:
56.3
5aqyA-3ldoA:
66.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
5 / 12 ALA A 204
VAL A 400
VAL A  50
GLY A  43
THR A 156
None
1.22A 5x24A-3ldoA:
undetectable
5x24A-3ldoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo
sapiens)
4 / 8 LEU A 161
TYR A 160
GLU A  51
THR A  29
None
1.01A 6c71B-3ldoA:
undetectable
6c71B-3ldoA:
12.50