SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ldr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 TYR A 232
GLY A 342
PHE A 298
VAL A 311
ALA A 198
 None
 1.29A 1e3vA-3ldrA:
undetectable		 1e3vA-3ldrA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 4 LYS A 351
LEU A 265
ALA A 350
LEU A 248
 None
 1.49A 1f86B-3ldrA:
undetectable		 1f86B-3ldrA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 THR A 314
LEU A 427
TYR A 393
GLY A 373
ALA A 371
 None
 1.02A 1httC-3ldrA:
undetectable		 1httC-3ldrA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 GLY A 365
SER A 612
GLU A 570
LEU A 422
HIS A 332
 None
 1.24A 1kyvA-3ldrA:
undetectable
1kyvE-3ldrA:
undetectable		 1kyvA-3ldrA:
14.83
1kyvE-3ldrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 11 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.26A 1kyvA-3ldrA:
undetectable
1kyvB-3ldrA:
undetectable		 1kyvA-3ldrA:
14.83
1kyvB-3ldrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.24A 1kyvB-3ldrA:
undetectable
1kyvC-3ldrA:
undetectable		 1kyvB-3ldrA:
14.83
1kyvC-3ldrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.24A 1kyvC-3ldrA:
undetectable
1kyvD-3ldrA:
undetectable		 1kyvC-3ldrA:
14.83
1kyvD-3ldrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.23A 1kyvD-3ldrA:
undetectable
1kyvE-3ldrA:
undetectable		 1kyvD-3ldrA:
14.83
1kyvE-3ldrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.39A 1v8bA-3ldrA:
undetectable		 1v8bA-3ldrA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 GLU A 302
GLU A 426
LEU A 463
 None
 0.62A 1v8bA-3ldrA:
undetectable		 1v8bA-3ldrA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.38A 1v8bB-3ldrA:
undetectable		 1v8bB-3ldrA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.41A 1v8bD-3ldrA:
undetectable		 1v8bD-3ldrA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 11 GLY A 365
SER A 612
GLU A 570
LEU A 422
HIS A 332
 None
 1.26A 2a58A-3ldrA:
undetectable
2a58E-3ldrA:
undetectable		 2a58A-3ldrA:
15.00
2a58E-3ldrA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.28A 2a58A-3ldrA:
undetectable
2a58B-3ldrA:
undetectable		 2a58A-3ldrA:
15.00
2a58B-3ldrA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.26A 2a58B-3ldrA:
undetectable
2a58C-3ldrA:
undetectable		 2a58B-3ldrA:
15.00
2a58C-3ldrA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 11 HIS A 332
GLY A 365
SER A 612
GLU A 570
LEU A 422
 None
 1.26A 2a58C-3ldrA:
undetectable
2a58D-3ldrA:
undetectable		 2a58C-3ldrA:
15.00
2a58D-3ldrA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 THR A 273
GLY A 243
GLY A 238
GLU A 267
GLN A 270
 None
 1.32A 2akeA-3ldrA:
undetectable		 2akeA-3ldrA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 GLY A 238
PHE A 291
VAL A 235
ALA A 188
TYR A 149
 None
 1.49A 2avdA-3ldrA:
undetectable		 2avdA-3ldrA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 8 VAL A 202
VAL A 221
LEU A 203
ASP A 222
 None
 1.05A 2ddwA-3ldrA:
undetectable		 2ddwA-3ldrA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 HIS A  50
ARG A 425
LEU A 399
SER A 612
 None
 1.46A 2qhfA-3ldrA:
undetectable		 2qhfA-3ldrA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 4 LYS A 351
LEU A 265
ALA A 350
LEU A 248
 None
 1.41A 2roxA-3ldrA:
undetectable		 2roxA-3ldrA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 8 PRO A 124
VAL A 122
ALA A 161
PRO A  68
 None
 0.94A 2v32A-3ldrA:
undetectable
2v32B-3ldrA:
undetectable		 2v32A-3ldrA:
14.98
2v32B-3ldrA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 8 PRO A  68
PRO A 124
VAL A 122
ALA A 161
 None
 0.96A 2v32A-3ldrA:
undetectable
2v32B-3ldrA:
undetectable		 2v32A-3ldrA:
14.98
2v32B-3ldrA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 ARG A 250
GLU A 208
SER A 197
 None
 0.85A 2xkkA-3ldrA:
undetectable
2xkkC-3ldrA:
undetectable		 2xkkA-3ldrA:
20.56
2xkkC-3ldrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 GLU A 602
VAL A 595
LEU A 475
TYR A 647
TYR A  95
 None
 1.24A 2ziaB-3ldrA:
undetectable		 2ziaB-3ldrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.21A 3bjwA-3ldrA:
undetectable		 3bjwA-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.21A 3bjwG-3ldrA:
undetectable		 3bjwG-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.20A 3bjwC-3ldrA:
undetectable		 3bjwC-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 VAL A 594
VAL A 595
THR A 537
THR A 509
 None
 1.23A 3bjwD-3ldrA:
undetectable		 3bjwD-3ldrA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 7 PHE A 577
VAL A 579
VAL A 441
ASN A 434
 None
 0.95A 3kmoB-3ldrA:
undetectable		 3kmoB-3ldrA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.38A 3n58D-3ldrA:
undetectable		 3n58D-3ldrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 6 SER A 367
HIS A  50
THR A 613
ARG A 552
 None
 1.36A 3thrB-3ldrA:
undetectable		 3thrB-3ldrA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 THR A 187
GLY A 237
PRO A 244
ASN A 290
 None
 0.95A 3u8qA-3ldrA:
undetectable		 3u8qA-3ldrA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 TRP A  45
TRP A 618
THR A  25
 None
 1.42A 4bboB-3ldrA:
undetectable		 4bboB-3ldrA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 6 THR A 187
GLY A 237
PRO A 244
ASN A 290
 None
 0.90A 4fjpA-3ldrA:
undetectable		 4fjpA-3ldrA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 SER A 612
LEU A 611
PHE A 609
TYR A 604
GLY A 360
 None
 1.19A 4j7xA-3ldrA:
undetectable		 4j7xA-3ldrA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 SER A 612
LEU A 611
PHE A 609
TYR A 604
GLY A 360
 None
 1.20A 4j7xB-3ldrA:
undetectable		 4j7xB-3ldrA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 SER A 612
LEU A 611
PHE A 609
TYR A 604
GLY A 360
 None
 1.19A 4j7xF-3ldrA:
undetectable		 4j7xF-3ldrA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 LEU A 475
LYS A 472
THR A 471
 None
 0.60A 4lj0A-3ldrA:
undetectable		 4lj0A-3ldrA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 SER A 157
ALA A 159
VAL A 160
 None
 0.58A 4x1iA-3ldrA:
undetectable		 4x1iA-3ldrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 ASP A 363
ARG A 616
ARG A 552
 None
 0.87A 4x5iA-3ldrA:
undetectable		 4x5iA-3ldrA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 5 GLY A 344
GLY A 349
GLU A 348
 None
 0.49A 4z2eA-3ldrA:
undetectable
4z2eD-3ldrA:
undetectable		 4z2eA-3ldrA:
21.57
4z2eD-3ldrA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 7 PRO A  28
LEU A 534
GLU A 535
TYR A 619
 None
 1.05A 4z4fA-3ldrA:
undetectable		 4z4fA-3ldrA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 VAL A 382
HIS A  64
VAL A 394
 None
 0.71A 5jmnC-3ldrA:
undetectable		 5jmnC-3ldrA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.33A 5m66A-3ldrA:
undetectable		 5m66A-3ldrA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 7 PRO A  28
LEU A 534
GLU A 535
TYR A 619
 None
 1.03A 5t7bA-3ldrA:
undetectable		 5t7bA-3ldrA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A 574
GLY A 360
SER A 547
LEU A 548
LEU A 611
 None
 0.97A 5twjA-3ldrA:
undetectable		 5twjA-3ldrA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 12 LEU A  78
ASP A  60
THR A 293
LEU A 421
HIS A  64
 None
DQR  A3168 (-2.5A)
DQR  A3168 ( 4.9A)
None
None
 1.37A 5utuF-3ldrA:
undetectable		 5utuF-3ldrA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 PHE A 628
PHE A 627
LEU A 489
LEU A 592
 None
 1.15A 5veuH-3ldrA:
undetectable		 5veuH-3ldrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		5 / 8 PRO A 192
ALA A 178
THR A 155
THR A 136
ALA A 159
 None
 1.35A 5x2tI-3ldrA:
undetectable
5x2tJ-3ldrA:
undetectable
5x2tK-3ldrA:
undetectable
5x2tL-3ldrA:
undetectable		 5x2tI-3ldrA:
11.11
5x2tJ-3ldrA:
11.99
5x2tK-3ldrA:
11.11
5x2tL-3ldrA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 5 LEU A 475
VAL A 595
GLU A 602
LEU A 423
 None
 0.97A 5xooB-3ldrA:
undetectable		 5xooB-3ldrA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 4 LYS A 351
LEU A 265
ALA A 350
LEU A 248
 None
 1.43A 6gnrA-3ldrA:
undetectable		 6gnrA-3ldrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		4 / 4 LYS A 351
LEU A 265
ALA A 350
LEU A 248
 None
 1.43A 6gnrB-3ldrA:
undetectable		 6gnrB-3ldrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 ASN A 112
PRO A 175
GLN A 260
 None
 0.95A 6jnhA-3ldrA:
undetectable		 6jnhA-3ldrA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3ldr FRUCTOSYLTRANSFERASE
(Aspergillus
japonicus) 		3 / 3 ASN A 112
PRO A 175
GLN A 260
 None
 0.95A 6jogA-3ldrA:
undetectable		 6jogA-3ldrA:
14.93