SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ldt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZTH_A_SAMA305_1 (CATECHOL O-METHYLTRANSFERASE)	3ldt	OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN (Legionella pneumophila)	3 / 3	SER A 182 GLU A 230 ASP A 170	None	0.81A	2zthA-3ldtA: undetectable	2zthA-3ldtA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QX3_D_EVPD1_1 (DNA TOPOISOMERASE 2-BETA)	3ldt	OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN (Legionella pneumophila)	4 / 5	GLY A 207 ASP A 210 GLN A 185 MET A 134	None	1.31A	3qx3B-3ldtA: undetectable	3qx3B-3ldtA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUD_A_SAMA303_1 (CATECHOL O-METHYLTRANSFERASE)	3ldt	OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN (Legionella pneumophila)	3 / 3	SER A 182 GLU A 230 ASP A 170	None	0.85A	4xudA-3ldtA: undetectable	4xudA-3ldtA: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_2 (TUBULIN BETA CHAIN)	3ldt	OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN (Legionella pneumophila)	4 / 5	LEU A 155 LEU A 109 THR A 124 ARG A 227	None	1.09A	6ew0F-3ldtA: undetectable	6ew0F-3ldtA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	3ldt	OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN (Legionella pneumophila)	4 / 6	LEU A 155 LEU A 109 THR A 124 ARG A 227	None	1.09A	6ew0G-3ldtA: undetectable	6ew0G-3ldtA: 17.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZTH_A_SAMA305_1","CATECHOL O-METHYLTRANSFERASE","3ldt","OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN","Legionella pneumophila",3,"SER A 182;GLU A 230;ASP A 170","None","0.81A","2zthA-3ldtA:undetectable","2zthA-3ldtA:20.27"],["3QX3_D_EVPD1_1","DNA TOPOISOMERASE 2-BETA","3ldt","OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN","Legionella pneumophila",4,"GLY A 207;ASP A 210;GLN A 185;MET A 134","None","1.31A","3qx3B-3ldtA:undetectable","3qx3B-3ldtA:13.33"],["4XUD_A_SAMA303_1","CATECHOL O-METHYLTRANSFERASE","3ldt","OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN","Legionella pneumophila",3,"SER A 182;GLU A 230;ASP A 170","None","0.85A","4xudA-3ldtA:undetectable","4xudA-3ldtA:22.02"],["6EW0_F_TA1F502_2","TUBULIN BETA CHAIN","3ldt","OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN","Legionella pneumophila",4,"LEU A 155;LEU A 109;THR A 124;ARG A 227","None","1.09A","6ew0F-3ldtA:undetectable","6ew0F-3ldtA:17.06"],["6EW0_G_TA1G501_2","TUBULIN BETA CHAIN","3ldt","OUTER MEMBRANE PROTEIN, OMPA FAMILY PROTEIN","Legionella pneumophila",4,"LEU A 155;LEU A 109;THR A 124;ARG A 227","None","1.09A","6ew0G-3ldtA:undetectable","6ew0G-3ldtA:17.06"]]