SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3led'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 6 LYS A 255
GLY A 249
ASN A 238
PRO A 247
 None
 1.23A 1dedA-3ledA:
undetectable		 1dedA-3ledA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 9 LEU A 163
ILE A 222
VAL A 170
GLY A 171
ALA A   4
 None
 1.28A 1e7aA-3ledA:
undetectable		 1e7aA-3ledA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 VAL A 181
ALA A 207
HIS A 340
 None
 0.44A 1q23C-3ledA:
undetectable		 1q23C-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 103
VAL A 181
ALA A 207
HIS A 340
 None
 1.04A 1q23A-3ledA:
undetectable		 1q23A-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 103
VAL A 181
ALA A 207
HIS A 340
 None
 1.13A 1q23F-3ledA:
undetectable		 1q23F-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 VAL A 181
ALA A 207
HIS A 340
 None
 0.44A 1q23H-3ledA:
undetectable		 1q23H-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 VAL A 181
ALA A 207
HIS A 340
 None
 0.42A 1q23G-3ledA:
undetectable		 1q23G-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 103
VAL A 181
ALA A 207
HIS A 340
 None
 0.97A 1q23K-3ledA:
undetectable		 1q23K-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 VAL A 181
ALA A 207
HIS A 340
 None
 0.48A 1q23L-3ledA:
undetectable		 1q23L-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 VAL A 181
ALA A 207
HIS A 340
 None
 0.50A 1q23J-3ledA:
undetectable		 1q23J-3ledA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 LEU A 163
ALA A 207
ALA A 107
ALA A 208
VAL A 366
 None
 1.16A 1rbpA-3ledA:
undetectable		 1rbpA-3ledA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 GLU A 184
THR A 330
LEU A  11
 None
 0.72A 1v8bC-3ledA:
undetectable		 1v8bC-3ledA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 VAL A 268
SER A 126
SER A 158
ALA A 359
ILE A 200
 None
 1.36A 2qm9B-3ledA:
undetectable		 2qm9B-3ledA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 6 GLY A 358
GLY A 261
PHE A 257
PHE A 201
 None
 1.02A 2qx6A-3ledA:
undetectable
2qx6B-3ledA:
undetectable		 2qx6A-3ledA:
20.20
2qx6B-3ledA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 7 SER A 157
CYH A 156
GLN A 230
ILE A 235
 None
 1.27A 2xz5A-3ledA:
undetectable
2xz5B-3ledA:
undetectable		 2xz5A-3ledA:
16.76
2xz5B-3ledA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 PRO A 315
ASP A 314
GLU A 304
 None
 0.87A 3v4tC-3ledA:
undetectable		 3v4tC-3ledA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 5 LEU A 351
PHE A 367
PRO A 287
ALA A 280
 None
 1.35A 3vm4A-3ledA:
undetectable		 3vm4A-3ledA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 367
ILE A 306
ILE A   6
HIS A 279
VAL A 272
 None
 1.30A 4a97B-3ledA:
undetectable
4a97C-3ledA:
undetectable		 4a97B-3ledA:
25.93
4a97C-3ledA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 11 GLY A  10
ALA A 107
ILE A 209
LEU A 163
ILE A   6
 None
 1.06A 4dt8A-3ledA:
undetectable		 4dt8A-3ledA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 8 GLY A 334
ALA A 333
PRO A  14
THR A  13
 None
 0.81A 4eyrB-3ledA:
undetectable		 4eyrB-3ledA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 6 GLY A 261
PHE A 257
ILE A 235
PHE A 201
 None
 1.04A 4qogA-3ledA:
undetectable
4qogB-3ledA:
undetectable		 4qogA-3ledA:
20.20
4qogB-3ledA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 208
THR A 206
THR A   9
GLY A 162
ALA A 166
 None
 0.99A 4ypmA-3ledA:
undetectable		 4ypmA-3ledA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 334
PHE A  57
PHE A 199
HIS A 296
THR A 330
 None
 1.20A 4zdyA-3ledA:
undetectable		 4zdyA-3ledA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 334
PHE A  57
PHE A 199
HIS A 296
THR A 330
 None
 1.17A 4ze1A-3ledA:
undetectable		 4ze1A-3ledA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 334
PHE A  57
PHE A 199
HIS A 296
THR A 330
 None
 1.24A 5eslA-3ledA:
undetectable		 5eslA-3ledA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		3 / 3 SER A 356
LEU A 290
MET A 293
 None
 0.66A 5ikrB-3ledA:
undetectable		 5ikrB-3ledA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 338
PHE A  57
PHE A 199
HIS A 296
THR A 330
 None
 1.33A 5jlcA-3ledA:
undetectable		 5jlcA-3ledA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		4 / 6 TYR A 327
THR A  13
ASP A 203
GLY A 202
 None
 1.04A 5mraA-3ledA:
undetectable
5mraB-3ledA:
undetectable		 5mraA-3ledA:
17.86
5mraB-3ledA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 334
PHE A  57
PHE A 199
HIS A 296
THR A 330
 None
 1.15A 6e8qA-3ledA:
undetectable		 6e8qA-3ledA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3led 3-OXOACYL-ACYL
CARRIER PROTEIN
SYNTHASE III
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 358
GLY A 360
GLU A 267
VAL A 268
LEU A 271
 None
 1.03A 6ecxA-3ledA:
undetectable		 6ecxA-3ledA:
21.17