SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3lei PLATELET AGGREGATION
FACTOR SM-HPAF
(Streptococcus
mitis) 		4 / 8 ARG A 112
SER A 174
ASN A 116
ASP A 114
 FUC  A1186 (-3.0A)
None
None
None
 1.26A 1hwkA-3leiA:
undetectable		 1hwkA-3leiA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 3lei PLATELET AGGREGATION
FACTOR SM-HPAF
(Streptococcus
mitis) 		3 / 3 LEU A 166
LYS A 167
THR A 168
 None
 0.61A 4lj0A-3leiA:
undetectable		 4lj0A-3leiA:
15.92