SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lew'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 8 GLN A 437
ASN A 436
LEU A 412
LEU A 235
None
1.06A 1hk3A-3lewA:
0.8
1hk3A-3lewA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.45A 1k2sA-3lewA:
undetectable
1k2sB-3lewA:
0.0
1k2sA-3lewA:
19.56
1k2sB-3lewA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 SER A 158
ALA A 160
SER A 190
ALA A 167
None
1.06A 1k5qA-3lewA:
undetectable
1k5qB-3lewA:
undetectable
1k5qA-3lewA:
17.40
1k5qB-3lewA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 LEU A 393
GLU A 422
LEU A 423
GLU A 426
None
0.86A 1linA-3lewA:
undetectable
1linA-3lewA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.44A 1p6jA-3lewA:
undetectable
1p6jB-3lewA:
undetectable
1p6jA-3lewA:
19.36
1p6jB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.43A 1p6jA-3lewA:
undetectable
1p6jB-3lewA:
undetectable
1p6jA-3lewA:
19.36
1p6jB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TYR A 290
TYR A 304
TYR A 294
PHE A 352
None
1.14A 2ajvH-3lewA:
undetectable
2ajvL-3lewA:
undetectable
2ajvH-3lewA:
15.72
2ajvL-3lewA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 ALA A 170
TYR A 150
TYR A 112
ILE A 172
None
None
1PE  A   5 (-3.6A)
None
1.16A 2dcfA-3lewA:
undetectable
2dcfA-3lewA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.45A 2hx4A-3lewA:
undetectable
2hx4B-3lewA:
undetectable
2hx4A-3lewA:
19.36
2hx4B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 GLU A 369
LEU A 151
ARG A 419
ASP A 432
TYR A  66
None
1.40A 2no6A-3lewA:
undetectable
2no6A-3lewA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
3 / 3 TYR A 112
GLU A 497
ASN A 503
1PE  A   5 (-3.6A)
1PE  A   5 (-2.6A)
None
0.80A 2y7hC-3lewA:
undetectable
2y7hC-3lewA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ALA A 170
TYR A 150
TYR A 112
ILE A 172
None
None
1PE  A   5 (-3.6A)
None
1.16A 2zm7A-3lewA:
undetectable
2zm7A-3lewA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 PHE A 428
SER A 155
HIS A 152
LEU A  70
TYR A  66
None
1.47A 3adsA-3lewA:
undetectable
3adsA-3lewA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 10 GLY A 101
GLY A 102
THR A 103
ASN A  59
ILE A  97
None
None
None
1PE  A  12 (-3.9A)
None
1.21A 3fw1A-3lewA:
undetectable
3fw1A-3lewA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 10 PHE A  88
GLY A 101
GLY A 102
THR A 105
ASN A  63
None
1.09A 3fw1A-3lewA:
undetectable
3fw1A-3lewA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 8 ASN A 223
GLU A 203
TYR A 246
LEU A 227
1PE  A   7 (-3.0A)
1PE  A  13 ( 4.9A)
None
1PE  A   7 ( 4.9A)
1.05A 3rqwC-3lewA:
2.0
3rqwD-3lewA:
2.0
3rqwC-3lewA:
19.53
3rqwD-3lewA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 8 ASN A 223
GLU A 203
TYR A 246
LEU A 227
1PE  A   7 (-3.0A)
1PE  A  13 ( 4.9A)
None
1PE  A   7 ( 4.9A)
1.06A 3rqwI-3lewA:
undetectable
3rqwJ-3lewA:
undetectable
3rqwI-3lewA:
19.53
3rqwJ-3lewA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 8 GLU A 203
TYR A 246
LEU A 227
ASN A 223
1PE  A  13 ( 4.9A)
None
1PE  A   7 ( 4.9A)
1PE  A   7 (-3.0A)
1.06A 3rqwF-3lewA:
1.6
3rqwJ-3lewA:
undetectable
3rqwF-3lewA:
19.53
3rqwJ-3lewA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
3 / 3 ASN A 436
TRP A 416
ASP A 162
None
1.20A 4a7tA-3lewA:
undetectable
4a7tF-3lewA:
undetectable
4a7tA-3lewA:
14.32
4a7tF-3lewA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.45A 4d2zA-3lewA:
undetectable
4d2zB-3lewA:
undetectable
4d2zA-3lewA:
19.36
4d2zB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
3 / 3 ARG A 492
TYR A  66
ASN A  63
None
0.96A 4ffwB-3lewA:
undetectable
4ffwB-3lewA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.39A 4jshA-3lewA:
undetectable
4jshB-3lewA:
undetectable
4jshA-3lewA:
19.36
4jshB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.43A 4kciA-3lewA:
undetectable
4kciB-3lewA:
undetectable
4kciA-3lewA:
19.36
4kciB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 ARG A  71
GLY A 427
ILE A 431
PHE A 148
TYR A 236
None
1.33A 4kotA-3lewA:
undetectable
4kotA-3lewA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 5 TYR A  66
HIS A 152
ASP A  74
ASP A  79
None
1.17A 4qdjA-3lewA:
undetectable
4qdjA-3lewA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.43A 4ugzA-3lewA:
undetectable
4ugzB-3lewA:
undetectable
4ugzA-3lewA:
19.36
4ugzB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.43A 4uh0A-3lewA:
undetectable
4uh0B-3lewA:
undetectable
4uh0A-3lewA:
19.36
4uh0B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.43A 4uh0A-3lewA:
undetectable
4uh0B-3lewA:
undetectable
4uh0A-3lewA:
19.36
4uh0B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.42A 4upnA-3lewA:
undetectable
4upnB-3lewA:
undetectable
4upnA-3lewA:
19.36
4upnB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 GLY A 101
GLY A 102
THR A 103
ASN A  59
ILE A  97
None
None
None
1PE  A  12 (-3.9A)
None
1.24A 4zvmA-3lewA:
undetectable
4zvmB-3lewA:
undetectable
4zvmA-3lewA:
20.05
4zvmB-3lewA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.43A 5ad5A-3lewA:
undetectable
5ad5B-3lewA:
undetectable
5ad5A-3lewA:
19.36
5ad5B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.42A 5ad6A-3lewA:
undetectable
5ad6B-3lewA:
0.0
5ad6A-3lewA:
19.36
5ad6B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.41A 5ad7A-3lewA:
undetectable
5ad7B-3lewA:
undetectable
5ad7A-3lewA:
19.36
5ad7B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.41A 5ad8A-3lewA:
0.0
5ad8B-3lewA:
0.0
5ad8A-3lewA:
19.36
5ad8B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.41A 5adaA-3lewA:
undetectable
5adaB-3lewA:
0.0
5adaA-3lewA:
19.36
5adaB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 ASP A 432
SER A 155
PHE A 148
ARG A 366
LEU A  70
None
1.44A 5m54B-3lewA:
undetectable
5m54B-3lewA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.42A 5unrA-3lewA:
undetectable
5unrB-3lewA:
undetectable
5unrA-3lewA:
19.36
5unrB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.42A 5unsA-3lewA:
undetectable
5unsB-3lewA:
undetectable
5unsA-3lewA:
19.36
5unsB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.40A 5unuA-3lewA:
undetectable
5unuB-3lewA:
0.0
5unuA-3lewA:
19.36
5unuB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.36A 5unuA-3lewA:
undetectable
5unuB-3lewA:
0.0
5unuA-3lewA:
19.36
5unuB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 6 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.45A 5unvA-3lewA:
undetectable
5unvB-3lewA:
0.0
5unvA-3lewA:
19.36
5unvB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.42A 5unwA-3lewA:
undetectable
5unwB-3lewA:
0.0
5unwA-3lewA:
19.36
5unwB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.38A 5unzA-3lewA:
undetectable
5unzB-3lewA:
undetectable
5unzA-3lewA:
19.36
5unzB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.32A 5uo0A-3lewA:
undetectable
5uo0B-3lewA:
undetectable
5uo0A-3lewA:
19.36
5uo0B-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.42A 5uo2A-3lewA:
undetectable
5uo2B-3lewA:
undetectable
5uo2A-3lewA:
20.08
5uo2B-3lewA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.41A 5uo3A-3lewA:
undetectable
5uo3B-3lewA:
undetectable
5uo3A-3lewA:
20.08
5uo3B-3lewA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.43A 5uo3A-3lewA:
undetectable
5uo3B-3lewA:
undetectable
5uo3A-3lewA:
20.08
5uo3B-3lewA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.44A 5vuiA-3lewA:
undetectable
5vuiB-3lewA:
undetectable
5vuiA-3lewA:
19.36
5vuiB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.40A 5vuiA-3lewA:
undetectable
5vuiB-3lewA:
undetectable
5vuiA-3lewA:
19.36
5vuiB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.41A 5vuoA-3lewA:
undetectable
5vuoB-3lewA:
undetectable
5vuoA-3lewA:
19.36
5vuoB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.42A 5vuqA-3lewA:
undetectable
5vuqB-3lewA:
undetectable
5vuqA-3lewA:
19.36
5vuqB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.39A 5vurA-3lewA:
undetectable
5vurB-3lewA:
undetectable
5vurA-3lewA:
19.36
5vurB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.43A 5vusA-3lewA:
undetectable
5vusB-3lewA:
undetectable
5vusA-3lewA:
19.36
5vusB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.41A 5vusA-3lewA:
undetectable
5vusB-3lewA:
undetectable
5vusA-3lewA:
19.36
5vusB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.41A 5vuuA-3lewA:
undetectable
5vuuB-3lewA:
0.0
5vuuA-3lewA:
19.36
5vuuB-3lewA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.42A 5vv5A-3lewA:
undetectable
5vv5B-3lewA:
undetectable
5vv5A-3lewA:
20.08
5vv5B-3lewA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 GLY A  67
ALA A  68
PHE A 307
SER A 306
PHE A 352
None
1.30A 5wbvA-3lewA:
undetectable
5wbvA-3lewA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 GLY A  67
ALA A  68
PHE A 307
SER A 306
PHE A 352
None
1.29A 5wbvB-3lewA:
undetectable
5wbvB-3lewA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
5 / 12 SER A 429
THR A  90
LEU A  70
PHE A 307
LEU A 295
None
1.37A 6a93A-3lewA:
2.3
6a93A-3lewA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.43A 6autA-3lewA:
undetectable
6autB-3lewA:
undetectable
6autA-3lewA:
9.81
6autB-3lewA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.42A 6auxA-3lewA:
undetectable
6auxB-3lewA:
undetectable
6auxA-3lewA:
9.81
6auxB-3lewA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.40A 6auxA-3lewA:
undetectable
6auxB-3lewA:
undetectable
6auxA-3lewA:
9.81
6auxB-3lewA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 ARG A 215
VAL A 363
TRP A 275
GLU A 274
2PE  A   4 ( 4.6A)
None
None
None
1.43A 6av5A-3lewA:
0.0
6av5B-3lewA:
undetectable
6av5A-3lewA:
10.19
6av5B-3lewA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 7 TRP A 275
GLU A 274
ARG A 215
VAL A 363
None
None
2PE  A   4 ( 4.6A)
None
1.42A 6av5A-3lewA:
0.0
6av5B-3lewA:
undetectable
6av5A-3lewA:
10.19
6av5B-3lewA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)
3lew SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN

(Bacteroides
vulgatus)
4 / 8 ALA A 142
GLY A 147
ALA A 205
GLU A 204
None
0.83A 6mdqA-3lewA:
undetectable
6mdqA-3lewA:
10.53