SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 11 VAL A  63
VAL A  16
SER A  76
LEU A  20
ALA A   6
 None
 1.02A 1eqgB-3lf0A:
undetectable		 1eqgB-3lf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  69
ALA A  23
VAL A  63
MET A   1
LEU A 112
 None
 0.86A 3s79A-3lf0A:
undetectable		 3s79A-3lf0A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7S_A_EXMA601_1
(CYTOCHROME P450 19A1)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 9 ILE A  69
ALA A  23
VAL A  63
MET A   1
LEU A 112
 None
 0.87A 3s7sA-3lf0A:
0.0		 3s7sA-3lf0A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 10 ILE A  69
ALA A  23
VAL A  63
MET A   1
LEU A 112
 None
 0.89A 4kq8A-3lf0A:
undetectable		 4kq8A-3lf0A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  69
ALA A  23
VAL A  63
MET A   1
LEU A 112
 None
 0.87A 5jkvA-3lf0A:
undetectable		 5jkvA-3lf0A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3lf0 NITROGEN REGULATORY
PROTEIN P-II
(Mycobacterium
tuberculosis) 		5 / 12 LEU A   3
VAL A  65
VAL A  25
GLY A  27
LEU A  13
 None
 0.83A 5x24A-3lf0A:
undetectable		 5x24A-3lf0A:
11.89