SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  74
ALA A 128
LEU A  91
PHE A 129
 None
 0.98A 1q97B-3lf2A:
undetectable		 1q97B-3lf2A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  15
ARG A  40
ARG A  44
ASP A  67
ALA A  95
 NDP  A 301 (-3.2A)
NDP  A 301 (-3.7A)
NDP  A 301 (-3.9A)
NDP  A 301 (-3.6A)
NDP  A 301 (-3.6A)
 0.95A 2bm9A-3lf2A:
7.2		 2bm9A-3lf2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  15
ARG A  40
ARG A  44
ASP A  67
ALA A  95
 NDP  A 301 (-3.2A)
NDP  A 301 (-3.7A)
NDP  A 301 (-3.9A)
NDP  A 301 (-3.6A)
NDP  A 301 (-3.6A)
 0.88A 2br4C-3lf2A:
5.8		 2br4C-3lf2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 239
LEU A 240
GLY A  21
SER A  18
ILE A  20
 None
None
None
NDP  A 301 (-3.7A)
None
 1.33A 2ycjA-3lf2A:
2.5		 2ycjA-3lf2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 190
SER A 146
SER A 262
ILE A 224
LEU A 191
 None
CL  A 302 ( 4.0A)
None
None
None
 1.20A 3iv6D-3lf2A:
8.5		 3iv6D-3lf2A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		4 / 8 GLU A  26
TYR A   4
ARG A  55
PHE A  56
 None
 1.15A 3mjrD-3lf2A:
undetectable		 3mjrD-3lf2A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 SER A  17
ILE A 239
ALA A 243
LEU A  28
LEU A  85
 NDP  A 301 (-2.7A)
None
None
None
None
 0.99A 3vw1B-3lf2A:
undetectable		 3vw1B-3lf2A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  16
GLY A  21
GLU A  26
ALA A  63
LEU A  45
 NDP  A 301 ( 4.6A)
None
None
None
None
 1.08A 3vywA-3lf2A:
3.4		 3vywA-3lf2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		6 / 12 VAL A 166
ALA A 162
THR A 159
LEU A 115
LEU A 117
GLY A  96
 None
None
CL  A 302 ( 4.5A)
None
None
None
 1.27A 5h2uA-3lf2A:
undetectable		 5h2uA-3lf2A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		4 / 8 ALA A  11
ILE A 141
ALA A 140
LEU A 133
 None
 0.84A 5te8B-3lf2A:
undetectable		 5te8B-3lf2A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 153
LEU A 148
LEU A 261
LEU A 191
 None
CL  A 302 (-4.9A)
None
None
 1.07A 5yvnA-3lf2A:
undetectable		 5yvnA-3lf2A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 10 ARG A  53
ALA A  11
LEU A  28
LEU A  29
VAL A  25
 None
 1.25A 6g2pB-3lf2A:
5.0		 6g2pB-3lf2A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  74
VAL A  68
PHE A 129
ILE A 141
ASN A  93
 None
NDP  A 301 (-3.6A)
None
None
None
 1.41A 6mxtA-3lf2A:
undetectable		 6mxtA-3lf2A:
21.31