SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lfr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RLB_F_REAF177_1 (RETINOL BINDING PROTEIN)	3lfr	PUTATIVE METAL ION TRANSPORTER (Pseudomonas syringae group genomosp. 3)	5 / 11	LEU A 149 ALA A 137 ALA A 161 VAL A 179 LEU A 180	None	1.19A	1rlbF-3lfrA: undetectable	1rlbF-3lfrA: 20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	3lfr	PUTATIVE METAL ION TRANSPORTER (Pseudomonas syringae group genomosp. 3)	4 / 6	HIS A 94 PRO A 98 LEU A 173 ASP A 178	AMP A 1 (-3.4A) AMP A 1 (-4.9A) None AMP A 1 (-2.7A)	0.40A	3oi8A-3lfrA: 20.8	3oi8A-3lfrA: 42.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OI8_B_ADNB1_1 (UNCHARACTERIZED PROTEIN)	3lfr	PUTATIVE METAL ION TRANSPORTER (Pseudomonas syringae group genomosp. 3)	6 / 9	HIS A 94 PRO A 98 LEU A 173 THR A 175 GLU A 177 ASP A 178	AMP A 1 (-3.4A) AMP A 1 (-4.9A) None AMP A 1 (-3.1A) AMP A 1 ( 4.7A) AMP A 1 (-2.7A)	0.67A	3oi8A-3lfrA: 20.8 3oi8B-3lfrA: 21.1	3oi8A-3lfrA: 42.94 3oi8B-3lfrA: 42.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP6_A_B40A601_1 (TRANSPORTER)	3lfr	PUTATIVE METAL ION TRANSPORTER (Pseudomonas syringae group genomosp. 3)	4 / 5	ASP A 106 ASP A 165 PHE A 139 GLY A 168	None	1.25A	4xp6A-3lfrA: undetectable	4xp6A-3lfrA: 16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	3lfr	PUTATIVE METAL ION TRANSPORTER (Pseudomonas syringae group genomosp. 3)	4 / 4	LEU A 111 ILE A 76 PRO A 82 LEU A 86	None	1.20A	5eb3A-3lfrA: undetectable	5eb3A-3lfrA: 24.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RLB_F_REAF177_1","RETINOL BINDING PROTEIN","3lfr","PUTATIVE METAL ION TRANSPORTER","Pseudomonas syringae group genomosp. 3",5,"LEU A 149;ALA A 137;ALA A 161;VAL A 179;LEU A 180","None","1.19A","1rlbF-3lfrA:undetectable","1rlbF-3lfrA:20.67"],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","3lfr","PUTATIVE METAL ION TRANSPORTER","Pseudomonas syringae group genomosp. 3",4,"HIS A  94;PRO A  98;LEU A 173;ASP A 178","AMP A   1 (-3.4A);AMP A   1 (-4.9A);None;AMP A   1 (-2.7A)","0.40A","3oi8A-3lfrA:20.8","3oi8A-3lfrA:42.94"],["3OI8_B_ADNB1_1","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","3lfr","PUTATIVE METAL ION TRANSPORTER","Pseudomonas syringae group genomosp. 3",6,"HIS A  94;PRO A  98;LEU A 173;THR A 175;GLU A 177;ASP A 178","AMP A   1 (-3.4A);AMP A   1 (-4.9A);None;AMP A   1 (-3.1A);AMP A   1 ( 4.7A);AMP A   1 (-2.7A)","0.67A","3oi8A-3lfrA:20.8;3oi8B-3lfrA:21.1","3oi8A-3lfrA:42.94;3oi8B-3lfrA:42.94"],["4XP6_A_B40A601_1","TRANSPORTER","3lfr","PUTATIVE METAL ION TRANSPORTER","Pseudomonas syringae group genomosp. 3",4,"ASP A 106;ASP A 165;PHE A 139;GLY A 168","None","1.25A","4xp6A-3lfrA:undetectable","4xp6A-3lfrA:16.17"],["5EB3_A_UEGA202_1","YFIR","3lfr","PUTATIVE METAL ION TRANSPORTER","Pseudomonas syringae group genomosp. 3",4,"LEU A 111;ILE A  76;PRO A  82;LEU A  86","None","1.20A","5eb3A-3lfrA:undetectable","5eb3A-3lfrA:24.22"]]