SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 8 ARG A  77
ASN A  63
GLN A 103
ASN A  67
 None
 1.31A 1p6kA-3lgiA:
undetectable		 1p6kA-3lgiA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 8 ARG A  77
ASN A  63
GLN A 103
ASN A  67
 None
 1.28A 1p6kB-3lgiA:
undetectable		 1p6kB-3lgiA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 8 ARG A  77
ASN A  63
GLN A 103
ASN A  67
 None
 1.31A 1rs7B-3lgiA:
undetectable		 1rs7B-3lgiA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 8 ARG A  77
ASN A  63
GLN A 103
ASN A  67
 None
 1.32A 1zzqB-3lgiA:
undetectable		 1zzqB-3lgiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 8 ARG A  77
ASN A  63
GLN A 103
ASN A  67
 None
 1.27A 1zzuB-3lgiA:
undetectable		 1zzuB-3lgiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.78A 2pxcA-3lgiA:
undetectable		 2pxcA-3lgiA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 5 LEU A 190
GLY A 177
ILE A 151
ILE A 173
 None
 0.69A 2q9rA-3lgiA:
undetectable		 2q9rA-3lgiA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.92A 2wa2B-3lgiA:
undetectable		 2wa2B-3lgiA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.90A 3elwA-3lgiA:
undetectable		 3elwA-3lgiA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.79A 3embA-3lgiA:
undetectable		 3embA-3lgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 7 LEU A 117
LEU A 248
MET A 245
ILE A  84
 None
 0.93A 3gp0A-3lgiA:
undetectable		 3gp0A-3lgiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 7 VAL A 154
LEU A 212
MET A 213
ILE A 172
 None
 0.87A 3gp0A-3lgiA:
undetectable		 3gp0A-3lgiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.71A 3p97A-3lgiA:
undetectable		 3p97A-3lgiA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.79A 3p97C-3lgiA:
undetectable		 3p97C-3lgiA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.70A 4ctjA-3lgiA:
undetectable		 4ctjA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.80A 4ctjC-3lgiA:
undetectable		 4ctjC-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.69A 4ctkA-3lgiA:
undetectable		 4ctkA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.79A 4ctkC-3lgiA:
undetectable		 4ctkC-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 7 TYR A  62
VAL A  59
ILE A  91
ILE A 132
ALA A 116
 None
 1.19A 4lv9A-3lgiA:
undetectable		 4lv9A-3lgiA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 4 ASN A 216
VAL A  58
THR A 169
ILE A 168
 None
 1.30A 4retA-3lgiA:
undetectable		 4retA-3lgiA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 4 ASN A 216
VAL A 206
THR A 192
ILE A 173
 None
 1.47A 4retA-3lgiA:
undetectable		 4retA-3lgiA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 4 ASN A 216
VAL A  58
THR A 169
ILE A 168
 None
 1.30A 4retC-3lgiA:
undetectable		 4retC-3lgiA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		4 / 4 ASN A 216
VAL A 206
THR A 192
ILE A 173
 None
 1.47A 4retC-3lgiA:
undetectable		 4retC-3lgiA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.68A 5e9qA-3lgiA:
undetectable		 5e9qA-3lgiA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.85A 5e9qC-3lgiA:
undetectable		 5e9qC-3lgiA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.66A 5ec8A-3lgiA:
undetectable		 5ec8A-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.77A 5ec8C-3lgiA:
undetectable		 5ec8C-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.67A 5ehgA-3lgiA:
undetectable		 5ehgA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.78A 5ehgC-3lgiA:
undetectable		 5ehgC-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.69A 5ehiA-3lgiA:
undetectable		 5ehiA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.81A 5ehiC-3lgiA:
undetectable		 5ehiC-3lgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.70A 5eifA-3lgiA:
undetectable		 5eifA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.82A 5eifC-3lgiA:
undetectable		 5eifC-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.67A 5eiwA-3lgiA:
undetectable		 5eiwA-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.79A 5eiwC-3lgiA:
undetectable		 5eiwC-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.69A 5ekxA-3lgiA:
undetectable		 5ekxA-3lgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.71A 5ekxB-3lgiA:
undetectable		 5ekxB-3lgiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.79A 5ikmA-3lgiA:
undetectable		 5ikmA-3lgiA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.77A 5kqrA-3lgiA:
undetectable		 5kqrA-3lgiA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.75A 5kqsA-3lgiA:
undetectable		 5kqsA-3lgiA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.82A 5m5bA-3lgiA:
undetectable		 5m5bA-3lgiA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 202
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.47A 5n0sA-3lgiA:
undetectable		 5n0sA-3lgiA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 203
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.26A 5n0sA-3lgiA:
undetectable		 5n0sA-3lgiA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 202
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.46A 5n0tA-3lgiA:
undetectable		 5n0tA-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 203
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.30A 5n0tA-3lgiA:
undetectable		 5n0tA-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 202
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.46A 5n0wB-3lgiA:
undetectable		 5n0wB-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 203
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.30A 5n0wB-3lgiA:
undetectable		 5n0wB-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 ILE A 215
GLY A 203
VAL A  61
ILE A 244
ALA A 241
 None
 1.06A 5n0xA-3lgiA:
undetectable		 5n0xA-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 202
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.45A 5n4iA-3lgiA:
undetectable		 5n4iA-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		6 / 12 ILE A 215
GLY A 203
VAL A  59
VAL A  61
ILE A 244
ALA A 241
 None
 1.30A 5n4iA-3lgiA:
undetectable		 5n4iA-3lgiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.75A 5njvA-3lgiA:
undetectable		 5njvA-3lgiA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.73A 5njvB-3lgiA:
undetectable		 5njvB-3lgiA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.78A 5njvC-3lgiA:
undetectable		 5njvC-3lgiA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.87A 5njvD-3lgiA:
undetectable		 5njvD-3lgiA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.74A 5vimA-3lgiA:
undetectable		 5vimA-3lgiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.72A 5vimB-3lgiA:
undetectable		 5vimB-3lgiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.77A 5wz1B-3lgiA:
undetectable		 5wz1B-3lgiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.73A 5wz2A-3lgiA:
undetectable		 5wz2A-3lgiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.70A 5wz2B-3lgiA:
undetectable		 5wz2B-3lgiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3lgi PROTEASE DEGS
(Escherichia
coli) 		5 / 12 GLY A 214
GLY A  82
GLY A 202
VAL A 106
ILE A  91
 None
 0.72A 5wz2C-3lgiA:
undetectable		 5wz2C-3lgiA:
22.73