SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lh4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3lh4	SECRETED CYSTATIN (Ixodes scapularis)	4 / 6	ILE A 106 ARG A 60 THR A 62 LEU A 63	None SO4 A 115 (-3.0A) None None	1.02A	3wg7N-3lh4A: undetectable 3wg7W-3lh4A: undetectable	3wg7N-3lh4A: 9.64 3wg7W-3lh4A: 16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3lh4	SECRETED CYSTATIN (Ixodes scapularis)	4 / 6	ILE A 106 ARG A 60 THR A 62 LEU A 63	None SO4 A 115 (-3.0A) None None	1.04A	5z86N-3lh4A: undetectable 5z86W-3lh4A: undetectable	5z86N-3lh4A: 9.64 5z86W-3lh4A: 16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3lh4	SECRETED CYSTATIN (Ixodes scapularis)	4 / 6	ILE A 106 ARG A 60 THR A 62 LEU A 63	None SO4 A 115 (-3.0A) None None	1.02A	5zcoN-3lh4A: undetectable 5zcoW-3lh4A: undetectable	5zcoN-3lh4A: 9.64 5zcoW-3lh4A: 16.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3WG7_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3lh4","SECRETED CYSTATIN","Ixodes scapularis",4,"ILE A 106;ARG A  60;THR A  62;LEU A  63","None;SO4 A 115 (-3.0A);None;None","1.02A","3wg7N-3lh4A:undetectable;3wg7W-3lh4A:undetectable","3wg7N-3lh4A:9.64;3wg7W-3lh4A:16.38"],["5Z86_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3lh4","SECRETED CYSTATIN","Ixodes scapularis",4,"ILE A 106;ARG A  60;THR A  62;LEU A  63","None;SO4 A 115 (-3.0A);None;None","1.04A","5z86N-3lh4A:undetectable;5z86W-3lh4A:undetectable","5z86N-3lh4A:9.64;5z86W-3lh4A:16.38"],["5ZCO_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3lh4","SECRETED CYSTATIN","Ixodes scapularis",4,"ILE A 106;ARG A  60;THR A  62;LEU A  63","None;SO4 A 115 (-3.0A);None;None","1.02A","5zcoN-3lh4A:undetectable;5zcoW-3lh4A:undetectable","5zcoN-3lh4A:9.64;5zcoW-3lh4A:16.38"]]