SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		3 / 3 ASP A  56
ASP A  58
ASN A  91
 None
 0.77A 2bm9D-3lhiA:
undetectable		 2bm9D-3lhiA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 6 PRO A 100
MET A 101
ASP A 114
TYR A 119
 None
 1.40A 2lh8A-3lhiA:
undetectable		 2lh8A-3lhiA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 8 PHE A 201
ILE A 214
TRP A   4
ILE A 182
 None
 0.98A 2qwxA-3lhiA:
undetectable
2qwxB-3lhiA:
2.5		 2qwxA-3lhiA:
22.35
2qwxB-3lhiA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 7 GLY A 133
SER A  40
ALA A  67
VAL A 217
 None
 0.75A 3a2qA-3lhiA:
undetectable		 3a2qA-3lhiA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 5 ASP A 155
GLY A 159
ASP A 180
THR A 178
 None
 0.95A 3vqrB-3lhiA:
undetectable		 3vqrB-3lhiA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 7 LEU A 218
ILE A 192
THR A 140
GLY A 138
 None
 0.95A 4eqlB-3lhiA:
undetectable		 4eqlB-3lhiA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3lhi PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 218
ILE A 192
THR A 140
GLY A 138
 None
 0.84A 4l39A-3lhiA:
undetectable		 4l39A-3lhiA:
16.32